DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr17 and dscam

DIOPT Version :9

Sequence 1:NP_001287297.1 Gene:dpr17 / 41470 FlyBaseID:FBgn0051361 Length:664 Species:Drosophila melanogaster
Sequence 2:XP_031751619.1 Gene:dscam / 100216449 XenbaseID:XB-GENE-921689 Length:2039 Species:Xenopus tropicalis


Alignment Length:741 Identity:141/741 - (19%)
Similarity:223/741 - (30%) Gaps:275/741 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 KGAVSVIAARNW---ATGT--ATQDWSQKSSSSWSSTSRRTGISRTR-TRPATLTT--------- 66
            |..||:::...:   :||.  .....::...:::..|:|......|| :..|.||.         
 Frog   162 KDTVSLVSGSRFLITSTGALYIADVQNEDGLNNYRCTTRHKYTGETRQSNSARLTVSDPANSAPS 226

  Fly    67 -----EMTVAGRAERAGVGAPWCRRFFHTSPLASWLRISFVLLVLPALGFGIQVVTC----SNPE 122
                 |...|...||  |..| |:...|..|...||:.:  :|:.|...|...||..    :.|.
 Frog   227 IIDGFEHHKAMAGER--VELP-CKASGHPIPKYRWLKNN--VLLEPDSRFQHTVVGLLIENTRPS 286

  Fly   123 LGASAPDPVDLTWGGKNTEGQLTTATRSTLPDSPMTTQNDLITTASNLATAKKPATAASEAVVDT 187
            ...|....|...:|.....|.|..       ..|:..         |::..|..::..|:..:..
 Frog   287 DSGSYVCEVWNNYGNAEVIGSLYV-------KQPLKV---------NISPRKVKSSVGSQISLAC 335

  Fly   188 AETAETAPPTEATSSWSSTAVARGMSSADGAGEAIATSQSAQI-GLTTQATVRQTEAQTASTATQ 251
            :.|....|..    ||...            ||.|....:.:| |:..:..:....|::.|.|.|
 Frog   336 SVTGTDDPDL----SWYRN------------GEIINAGNNVRITGVNRETLIMDGMAKSDSGAYQ 384

  Fly   252 AAAATSAATSAAIASAAAATETAAEMLISTIYPASTETDLHNSIERVEGQRGKMANAF-----HP 311
            ......              :.:|:..:..:               :|....|:.:||     .|
 Frog   385 CFVRRE--------------KMSAQDYVQVV---------------LEDGTPKIISAFSEKVVSP 420

  Fly   312 GVPDSL---TKGFSIPTF---LPPFPVFAAADLPAYRAAADAAEAAKLAAEAAAQAAAAKTSSEA 370
            |.|.||   .||..:||.   |...|:.                               |..:..
 Frog   421 GEPVSLMCNVKGTPLPTITWTLDDDPII-------------------------------KNGNHR 454

  Fly   371 VTMSPEEQRRQMFNEQH---SYL----AAHRDGG-------DGAGSAV---RRNL-----TMPVL 413
            ::        |:...:.   |||    ...||||       :.||..:   |.|:     ..|:.
 Frog   455 IS--------QLITSEGNVVSYLNITNTQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMK 511

  Fly   414 NITAQMGNHAYMPCQIHRLSDKPVSWVRMRD----NHIISVDETTFIADERFQSIYQEDHDYTWS 474
            ||||..|...|:.|::.......:.|.:..:    ||                  .|...:...:
 Frog   512 NITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNH------------------RQVAFENNGT 558

  Fly   475 LQIKYVEPS-DAGWYECQMATEPKLSA--KVHLQIVKPKTELIGDQSRFVKAGSKVALHCIVRGT 536
            |::..|:.. |.|.|.|.:..:|:||.  .||:.:..|......:..|| ..|.:|.:.|:|...
 Frog   559 LKLSDVQKDVDEGEYMCNVLVQPQLSTSQSVHVTVKVPPFIQPFESQRF-SIGQRVFIPCVVVSG 622

  Fly   537 LDPPKYIIW-------------------FRGQKKISD-SDERTGWYTQLDRNIFGTVGDNQN--- 578
             |.|..|.|                   |....:||: |....|.||.:.||....| ::|:   
 Frog   623 -DLPITITWQKDGRPIPASLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNDAAAV-EHQSQLI 685

  Fly   579 -------------------------------------------------------------TIGS 582
                                                                         |.||
 Frog   686 VRVPPRFVVQPTDQDGIYGKAVILNCSAEGYPVPTIVWKYSKGAGVPQFQPIALNGRIQLLTNGS 750

  Fly   583 LIIPLVRKEDSGNYTCQPSNSVSVSV 608
            |:|..|.:||||.|.|:.||.|...|
 Frog   751 LLIKHVLEEDSGYYLCKVSNDVGADV 776

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr17NP_001287297.1 IG_like 414..491 CDD:214653 16/81 (20%)
Ig 415..507 CDD:299845 21/98 (21%)
IG_like 521..612 CDD:214653 35/172 (20%)
IGc2 524..605 CDD:197706 33/164 (20%)
dscamXP_031751619.1 Ig 26..121 CDD:416386
Ig strand A' 33..37 CDD:409353
Ig strand B 40..49 CDD:409353
Ig strand C 55..61 CDD:409353
Ig strand C' 63..66 CDD:409353
Ig strand D 72..75 CDD:409353
Ig strand E 80..85 CDD:409353
Ig strand F 98..106 CDD:409353
Ig strand G 109..121 CDD:409353
Ig 124..217 CDD:416386 11/54 (20%)
Ig strand A' 127..136 CDD:409353
Ig strand B 140..147 CDD:409353
Ig strand C 157..162 CDD:409353 141/741 (19%)
Ig strand C' 164..167 CDD:409353 1/2 (50%)
Ig strand D 172..176 CDD:409353 0/3 (0%)
Ig strand E 179..185 CDD:409353 1/5 (20%)
Ig strand F 193..201 CDD:409353 1/7 (14%)
Ig strand G 205..217 CDD:409353 4/11 (36%)
Ig strand A 225..228 CDD:409353 0/2 (0%)
Ig strand A' 234..237 CDD:409353 0/2 (0%)
IG_like 236..310 CDD:214653 21/78 (27%)
Ig strand B 242..249 CDD:409353 3/7 (43%)
Ig strand C 255..260 CDD:409353 1/4 (25%)
Ig strand C' 262..264 CDD:409353 0/3 (0%)
Ig strand D 270..274 CDD:409353 1/3 (33%)
Ig strand E 276..280 CDD:409353 1/3 (33%)
Ig strand F 289..297 CDD:409353 2/7 (29%)
Ig strand G 300..310 CDD:409353 3/9 (33%)
Ig 313..395 CDD:416386 17/120 (14%)
Ig strand A 314..319 CDD:409353 1/13 (8%)
Ig strand A' 322..326 CDD:409353 1/3 (33%)
Ig strand B 329..339 CDD:409353 1/9 (11%)
Ig strand C 344..350 CDD:409353 2/9 (22%)
Ig strand C' 351..354 CDD:409353 2/2 (100%)
Ig strand E 368..374 CDD:409353 0/5 (0%)
Ig strand F 381..389 CDD:409353 2/7 (29%)
Ig 406..501 CDD:416386 26/133 (20%)
Ig strand A 406..409 CDD:409353 0/2 (0%)
Ig strand A' 415..419 CDD:409353 0/3 (0%)
Ig strand B 422..431 CDD:409353 3/8 (38%)
Ig strand C 436..442 CDD:409353 2/5 (40%)
Ig strand C' 444..447 CDD:409353 0/2 (0%)
Ig strand D 452..460 CDD:409353 1/15 (7%)
Ig strand E 464..473 CDD:409353 3/8 (38%)
Ig strand F 480..488 CDD:409353 1/7 (14%)
Ig strand G 491..501 CDD:409353 2/9 (22%)
Ig 504..593 CDD:416386 23/106 (22%)
Ig strand A 505..507 CDD:409353 0/1 (0%)
Ig strand A' 512..516 CDD:409353 3/3 (100%)
Ig strand B 519..526 CDD:409353 1/6 (17%)
Ig strand C 533..539 CDD:409353 1/5 (20%)
Ig strand C' 540..542 CDD:409353 0/1 (0%)
Ig strand D 549..553 CDD:409353 1/3 (33%)
Ig strand E 557..563 CDD:409353 1/5 (20%)
Ig strand F 571..579 CDD:409353 3/7 (43%)
Ig strand G 583..593 CDD:409353 4/9 (44%)
Ig 596..686 CDD:416386 22/92 (24%)
Ig strand A 597..599 CDD:409353 0/1 (0%)
Ig strand A' 604..608 CDD:409353 2/4 (50%)
Ig strand B 611..620 CDD:409353 2/8 (25%)
Ig strand C 625..632 CDD:409353 3/6 (50%)
Ig strand C' 634..636 CDD:409353 0/1 (0%)
Ig strand D 643..648 CDD:409353 0/4 (0%)
Ig strand E 651..658 CDD:409353 1/6 (17%)
Ig strand F 665..673 CDD:409353 3/7 (43%)
Ig strand G 676..685 CDD:409353 2/9 (22%)
Ig_DSCAM 689..784 CDD:409397 16/88 (18%)
Ig strand B 707..711 CDD:409397 0/3 (0%)
Ig strand C 720..724 CDD:409397 0/3 (0%)
Ig strand E 749..753 CDD:409397 3/3 (100%)
Ig strand F 763..768 CDD:409397 2/4 (50%)
Ig strand G 777..780 CDD:409397 141/741 (19%)
Ig_DSCAM 785..885 CDD:409398
Ig strand B 805..809 CDD:409398
Ig strand C 818..822 CDD:409398
Ig strand E 849..853 CDD:409398
Ig strand F 863..868 CDD:409398
Ig strand G 876..879 CDD:409398
FN3 886..980 CDD:238020
FN3 987..1084 CDD:238020
FN3 1093..1185 CDD:238020
FN3 1190..1279 CDD:238020
Ig_3 <1303..1364 CDD:404760
Ig strand B 1304..1311 CDD:409353
Ig strand C 1317..1322 CDD:409353
Ig strand C' 1327..1333 CDD:409353
Ig strand D 1337..1341 CDD:409353
Ig strand E 1343..1347 CDD:409353
Ig strand F 1356..1364 CDD:409353
Ig strand G 1367..1377 CDD:409353
FN3 1381..1471 CDD:238020
FN3 1497..1568 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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