Protein Alignment ATP8B and AT1G26130

DIOPT Version :10

• Sequence 1: NP_731669.2
• Gene: ATP8B / 41469
• FlyBaseID: FBgn0037989
• Length: 1726
• Species: Drosophila melanogaster
• Sequence 2: NP_001185096.1
• Gene: AT1G26130 / 839154
• AraportID: AT1G26130
• Length: 1185
• Species: Arabidopsis thaliana
• Alignment Length: 1384
• Identity: 452/1384 - (32%)
• Similarity: 669/1384 - (48%)
• Gaps: 339/1384 - (24%)

  Fly   209 YHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTA 273
            |.:||::|:||:|.||||.:|.|||:|:||||||.:.:|...| ::..|.|:..:||..|:..|.
plant    59 YCDNYVRTTKYTLATFLPKSLFEQFRRVANFYFLVVGILSFTP-LAPYTAVSAIVPLTFVILATM 122

  Fly   274 VKDAYDDIQRHISDSQVNNRKSKTLR-NGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEP 337
            .|:..:|.:|...|.:|||||.:..| ||.....:|..::|||:::::.|:|..||.:|||:|..
plant   123 FKEGVEDWRRKQQDIEVNNRKVRVHRGNGNFDLREWKTLRVGDILKVEKNEFFPADLVLLSSSYE 187

  Fly   338 NGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQR 402
            :.:|::||..||||||||.||.|..|:.|.:.. :..:|...|.||.||..|..|.||:..:|::
plant   188 DAVCYVETMNLDGETNLKLKQGLEVTLSLREEL-NFRDFEAFIKCEDPNANLYSFVGTMDLKGEK 251

  Fly   403 FALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVS 467
            :.|..:::||||..||||.:.||||:|.|.|||::|||.....|.:.::|.::.||..:.|.:.|
plant   252 YPLSPQQLLLRGSKLRNTDYIYGVVIFTGPDTKVVQNSTDPPSKRSMIERKMDKIIYLMFLMVFS 316

  Fly   468 ICALFAIGCAIW------EGLIGQHFQLYLPWEHIIPKD----YIPTGATVIGLLVFFSYAIVLN 522
            :....::...||      .|::.:       | ::.|.|    :.|..|.:..:..|.: |::||
plant   317 LAFFGSVLFGIWTRDDFQNGVMER-------W-YLKPDDSSIFFDPKRAPMAAIYHFLT-ALMLN 372

  Fly   523 T-VVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQ 586
            : .:|||||||:|:::.:||..||.|..|||...:..|.|||:.|||||||:..|.||||||||.
plant   373 SYFIPISLYVSIEIVKVLQSIFINQDIHMYYEEADKPAHARTSNLNEELGQVGTILSDKTGTLTC 437

  Fly   587 NIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILV 651
            |.|.|.||||.|.:||
plant   438 NSMEFIKCSIAGTAYG------------------------------------------------- 453

  Fly   652 HKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGR 716
                                     |..:::|.      |.:||.|...|..|..:.::||.|.
plant   454 -------------------------RGVTEVEM------AMDKRKGSALVNQSNGNSTEDAVAA- 486

  Fly   717 LSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSS 781
             .|.:.|       ....:.||..|
plant   487 -EPAVKG-------FNFRDERIMDG---------------------------------------- 503

  Fly   782 HNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRV 846
                                                                    ||.:..|
plant   504 --------------------------------------------------------NWVTETH-- 510

  Fly   847 HALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLLALCHTVMAETVD---GKLEYQA 908
                                     .|.::.       ||:|||:||||:.| ||   ||:.|:|
plant   511 -------------------------ADVIQK-------FFQLLAVCHTVIPE-VDEDTGKISYEA 542

  Fly   909 QSPDEAALVSAARNFGFVFRTRTPNSITIE----VMGQTEE--YELLNILDFNNVRKRMSVILRR 967
            :||||||.|.|||..||.|.|||..:|::.    |.|:..|  |.:||:|:|::.:||||||::.
plant   543 ESPDEAAFVIAARELGFEFFTRTQTTISVRELDLVTGERVERLYSVLNVLEFSSSKKRMSVIVQD 607

  Fly   968 GD-SMVLYCKGADNVIYDRLHGGQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQ 1031
            .| .::|.|||||:|:::||.......:..|:||:|::|..|||||.||.|.|.|..|..:..|.
plant   608 QDGKLLLLCKGADSVMFERLSESGRKYEKETRDHVNEYADAGLRTLILAYRELDENEYEVFTERI 672

  Fly  1032 QEAALSMDS-REQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQE 1095
            .||..|:.: ||..::.:.|:||..:.|:|.||:|||||:|||..|..|..||||||||||||.|
plant   673 SEAKNSVSADREALIDEVTEKIEKNLVLLGATAVEDKLQNGVPDCINKLAQAGIKIWVLTGDKME 737

  Fly  1096 TAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMD 1160
            ||||||::|.||..::..:.|    ::|..|.|                       :|......|
plant   738 TAINIGFACSLLRRDMKQIII----NLETPEIQ-----------------------QLEKSGEKD 775

  Fly  1161 PLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGG 1225
            .::..:.: :...|.|:                                      |..:....||
plant   776 AIAAALKE-NVLHQITS--------------------------------------GKAQLKASGG 801

  Fly  1226 TASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKN 1290
            .|.       .|||:::|.||.:.|..:::..||::|..|.:|||||.:|.|||||..|:|....
plant   802 NAK-------AFALIIDGKSLAYALEEDMKGIFLELAIGCASVICCRSSPKQKALVTRLVKTGSG 859

  Fly  1291 AVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKF 1355
            ..|||||||||||.|::.|.|||||||.||:|||:|||.:|||||||||||||||.|.|.|:.|.
plant   860 QTTLAIGDGANDVGMLQEADIGVGISGVEGMQAVMSSDIAIAQFRYLERLLLVHGHWCYRRISKM 924

  Fly  1356 LRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEF 1420
            :.||||||..|......|..:..|||...::..::|:|::|:|||||:.||:|:||||....|:|
plant   925 ICYFFYKNITFGFTLFLYEAYTSFSATPAYNDWYLSLYSVFFTSLPVICLGIFDQDVSAPFCLKF 989

  Fly  1421 PRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKDGVSANGF----VVSDHMTLGAVV 1481
            |.||..|:::.||:.|..:..:.||..:::::|.:    .|..:.:..|    ..:....||..:
plant   990 PVLYQEGVQNLLFSWRRILSWMFHGFCSAIIIFFL----CKTSLESQAFNHEGKTAGRDILGGTM 1050

  Fly  1482 ATILIVDNTAQISLYTSYWTVVNHVTIWGSLV-WYFVLDYFYNYVI---GGPYVGSLTQAMKDLT 1542
            .|.::...:.|:.|..||:|::.||.:|||:| ||..|..:.:..|   ...|:..|.......:
plant  1051 YTCVVWVVSLQMVLTISYFTLIQHVVVWGSVVIWYLFLMVYGSLPIRMSTDAYMVFLEALAPAPS 1115

  Fly  1543 FWVTMLITVMALVAPVLAY 1561
            :|:|.|..|::.:.|...:
plant  1116 YWITTLFVVLSTMMPYFIF 1134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8B	NP_731669.2	Haloacid Dehalogenase-like Hydrolases	211..>602	CDD:473868	163/402 (41%)
		Haloacid Dehalogenase-like Hydrolases	<885..1456	CDD:473868	239/581 (41%)
AT1G26130	NP_001185096.1	ATPase-Plipid	59..1150	CDD:273734	452/1384 (33%)