Protein Alignment ATP8B and AT1G17500

DIOPT Version :10

• Sequence 1: NP_731669.2
• Gene: ATP8B / 41469
• FlyBaseID: FBgn0037989
• Length: 1726
• Species: Drosophila melanogaster
• Sequence 2: NP_173193.2
• Gene: AT1G17500 / 838324
• AraportID: AT1G17500
• Length: 1216
• Species: Arabidopsis thaliana
• Alignment Length: 1443
• Identity: 479/1443 - (33%)
• Similarity: 707/1443 - (48%)
• Gaps: 330/1443 - (22%)

  Fly   194 RRIRANDKEFNAQ--FKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSL 256
            |.:..|....:.:  .||.:||:.|::|:|.||.|..|.|||.|.||||||...:|.:.| :|..
plant    41 RTVYCNQPHMHKKKPLKYRSNYVSTTRYNLITFFPKCLYEQFHRAANFYFLVAAILSVFP-LSPF 104

  Fly   257 TPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLR-NGKLVEAKWSEVQVGDVIRLD 320
            ...:...||:.|:.|:.:|:|.:|..|.:.|.::|..|....: :|:....||.::.|||:::::
plant   105 NKWSMIAPLVFVVGLSMLKEALEDWSRFMQDVKINASKVYVHKSDGEFRRRKWKKISVGDIVKVE 169

  Fly   321 NNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERP 385
            .:.|..||.||||:|..:|:|::||..||||||||.|:.|..|:.|.| :||..:|.|.|.||.|
plant   170 KDGFFPADLLLLSSSYEDGICYVETMNLDGETNLKVKRSLEVTLSLDD-YDSFKDFTGIIRCEDP 233

  Fly   386 NNLLNKFDGTLIWRGQRFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGV 450
            |..|..|.|.|.:..|.|.||..:||||...||||.:.||||||.|.|||:||||.|:..|.:.:
plant   234 NPSLYTFVGNLEYERQIFPLDPSQILLRDSKLRNTPYVYGVVVFTGHDTKVMQNSTKSPSKRSRI 298

  Fly   451 DRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLP-WEHIIPKD----YIPTGATVIG 510
            ::.:::||..:::.|:.|..:.:.|.| ||      .:.::| |.::.|::    ..|:.....|
plant   299 EKTMDYIIYTLLVLLILISCISSSGFA-WE------TKFHMPKWWYLRPEEPENLTNPSNPVYAG 356

  Fly   511 LLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQY 575
            .:...:..::...::|||||||:||::.:|:..||.|..||...:...|.|||:.|||||||:..
plant   357 FVHLITALLLYGYLIPISLYVSIEVVKVLQASFINKDLHMYDSESGVPAHARTSNLNEELGQVDT 421

  Fly   576 IFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVA 640
            |.||||||||.|.|.|.||||.|.|||    :|:.| ||:...|.:
plant   422 ILSDKTGTLTCNQMDFLKCSIAGTSYG----VRSSE-VEVAAAQQM------------------- 462

  Fly   641 PPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSA 705
                  .:.|....||.::      ||:..||.      .|||     :::|
plant   463 ------AVDLDEHGEVSSR------TSTPRAQA------RDIE-----VESS------------- 491

  Fly   706 PSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQ 770
                       ::||:...|     .|.|:.|:..|
plant   492 -----------ITPRIPIKG-----FGFEDIRLMDG----------------------------- 511

  Fly   771 QTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAF 835
                                                                             
plant   512 ----------------------------------------------------------------- 511

  Fly   836 ATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLLALCHTVMAETV 900
              ||...||.                      |..||            |||:||:|||.:.|..
plant   512 --NWLREPHT----------------------DDILL------------FFRILAICHTAIPELN 540

  Fly   901 D--GKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEV----MGQT--EEYELLNILDFNNV 957
            :  ||..|:|:|||||:.::||..|||||..||.:|:.:..    .|||  .||::||:|||.:.
plant   541 EETGKYTYEAESPDEASFLTAASEFGFVFFKRTQSSVYVHERLSHSGQTIEREYKVLNLLDFTSK 605

  Fly   958 RKRMSVILRRGDSMV-LYCKGADNVIYDRLHGGQEDLKARTQDHLNKFAGEGLRTLALAERRLTE 1021
            ||||||::|..:..: |.|||||::|::||....:.....|..|||::...|||||||:.|:|.|
plant   606 RKRMSVVVRDEEGQILLLCKGADSIIFERLAKNGKVYLGPTTKHLNEYGEAGLRTLALSYRKLDE 670

  Fly  1022 QYYNDWRSRQQEAALSMDS-REQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIK 1085
            :.|:.|.:...:|..|:.| |::.|..|.:.||.::.|||.||:|||||.|||:.|..|..||:|
plant   671 EEYSAWNAEFHKAKTSIGSDRDELLERISDMIEKDLILVGATAVEDKLQKGVPQCIDKLAQAGLK 735

  Fly  1086 IWVLTGDKQETAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPF 1150
            :|||||||.||||||||||.||...:..:.|...|| |...:..:..|::|
plant   736 LWVLTGDKMETAINIGYSCSLLRQGMKQICITVVNS-EGASQDAKAVKDNI-------------- 785

  Fly  1151 DRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLF 1215
                           :.|.:..:|...|
plant   786 ---------------LNQITKAVQMVKL------------------------------------- 798

  Fly  1216 GDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKAL 1280
              ||            |.:..|||:::|.:|.:.|..|::.:||.:|..|.:||||||:|.||||
plant   799 --EK------------DPHAAFALIIDGKTLTYALEDEMKYQFLALAVDCASVICCRVSPKQKAL 849

  Fly  1281 VVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHG 1345
            |..|:|.....:|||||||||||.||:.|.|||||||.||:|||::||:||||||:|||||:|||
plant   850 VTRLVKEGTGKITLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHG 914

  Fly  1346 RWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQ 1410
            .|.|.|:.:.:.||||||.||.|...::..|.|||.|:|::..::.::|:..|||||:|||||||
plant   915 HWCYKRIAQMICYFFYKNIAFGLTLFYFEAFTGFSGQSVYNDYYLLLFNVVLTSLPVIALGVFEQ 979

  Fly  1411 DVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYG-VYKDGVSANGFVVSDH 1474
            |||.:..|:||.||..|.|:..|:....:..:.:|.::|||:|.:..| :|:.....:| ..:|.
plant   980 DVSSEICLQFPALYQQGKKNLFFDWYRILGWMGNGVYSSLVIFFLNIGIIYEQAFRVSG-QTADM 1043

  Fly  1475 MTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSL-VWY-FVLDYFYNYVIGGPYVGSLTQA 1537
            ..:|..:.|.:|.....||:|..|::|.:.||.||||: :|| ||..|   .::.....|::.:.
plant  1044 DAVGTTMFTCIIWAVNVQIALTVSHFTWIQHVLIWGSIGLWYLFVALY---GMMPPSLSGNIYRI 1105

  Fly  1538 MKDL-----TFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSLKKIHSRASSDVRR-TA 1596
            :.::     .:|:...:..:..|.|..|:..:...:|| |...|.|:.  |.:.|...|.|. |.
plant  1106 LVEILAPAPIYWIATFLVTVTTVLPYFAHISFQRFLHP-LDHHIIQEI--KYYKRDVEDRRMWTR 1167

  Fly  1597 SSRRGRRSVRSGY 1609
            ...:.|...:.|:
plant  1168 ERTKAREKTKIGF 1180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8B	NP_731669.2	Haloacid Dehalogenase-like Hydrolases	211..>602	CDD:473868	162/396 (41%)
		Haloacid Dehalogenase-like Hydrolases	<885..1456	CDD:473868	241/580 (42%)
AT1G17500	NP_173193.2	Haloacid Dehalogenase-like Hydrolases	58..1151	CDD:473868	468/1393 (34%)