Protein Alignment ATP8B and AT3G27870

DIOPT Version :9

• Sequence 1: NP_731669.2
• Gene: ATP8B / 41469
• FlyBaseID: FBgn0037989
• Length: 1726
• Species: Drosophila melanogaster
• Sequence 2: NP_189425.2
• Gene: AT3G27870 / 822407
• AraportID: AT3G27870
• Length: 1189
• Species: Arabidopsis thaliana
• Alignment Length: 1484
• Identity: 461/1484 - (31%)
• Similarity: 698/1484 - (47%)
• Gaps: 383/1484 - (25%)

  Fly   178 SQIRRRRSSYYFSENERRIRANDKEFN---AQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANF 239
            |||..|..|       |.:..||.: |   .|..|..||:.|:||:...|:|.:|.|||:|:||.
plant    29 SQIGSRGYS-------RVVFCNDPD-NPEALQLNYRGNYVSTTKYTAANFIPKSLFEQFRRVANI 85

  Fly   240 YFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTL-RNGKL 303
            |||.:..:...| ::..|..:...||:.|:..|.||:..:|::|...|.:.||||.:.| :.|..
plant    86 YFLVVAFVSFSP-LAPYTAPSVLAPLLIVIGATMVKEGVEDLRRRKQDVEANNRKVEVLGKTGTF 149

  Fly   304 VEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGD 368
            ||.||..::|||::::..:::..||.||||:|..:|:|::||..||||||||.|..|    |:..
plant   150 VETKWKNLRVGDLVKVHKDEYFPADLLLLSSSYEDGICYVETMNLDGETNLKLKHAL----EITS 210

  Fly   369 RHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQRFALDNEKILLRGCVLRNTQWCYGVVVFAGVD 433
            ..:|:.||.|.|.||.||..|..|.|||.:.|:::.|..::||||...|:||.:.||||||.|.|
plant   211 DEESIKNFRGMIKCEDPNEHLYSFVGTLYFEGKQYPLSPQQILLRDSKLKNTDYVYGVVVFTGHD 275

  Fly   434 TKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLI--------GQHFQLY 490
            ||:|||:.....|.:.:::.::.||  .:||  ||..:.|...:::.|:.        |:..:.|
plant   276 TKVMQNATDPPSKRSKIEKKMDQII--YILF--SILIVIAFTGSVFFGIATRRDMSDNGKLRRWY 336

  Fly   491 LPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTT 555
            |..:| ....|.|..|.......|.:..::...::|||||||:||::.:||..||.|:|||:..|
plant   337 LRPDH-TTVFYDPRRAVAAAFFHFLTALMLYGYLIPISLYVSIEVVKVLQSIFINQDQEMYHEET 400

  Fly   556 NTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQT 620
            :..|:|||:.|||||||:..|.||||||||.|.|.|.||||.|.:||
plant   401 DRPARARTSNLNEELGQVDTILSDKTGTLTCNSMEFVKCSIAGTAYG------------------ 447

  Fly   621 IFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERS 685
                                                                    |..:::|
plant   448 --------------------------------------------------------RGMTEVE-- 454

  Fly   686 APPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCM 750
                .|..|:.||.       ::.:..|...||.:             |::.:.|
plant   455 ----VALRKQKGLM-------TQEEVGDNESLSIK-------------EQKAVKG---------- 485

  Fly   751 QRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEE 815
                                                                             
plant   486 ----------------------------------------------------------------- 485

  Fly   816 PQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEE 880
                                                            |.::|..::|....::.
plant   486 ------------------------------------------------FNFWDERIVDGQWINQP 502

  Fly   881 HSHV---FFRLLALCHTVMAE--TVDGKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITI-EV 939
            ::.:   |||:||:|||.:.:  :..|::.|:|:||||||.|.|:|..||.|.:|:..||:: |:
plant   503 NAELIQKFFRVLAICHTAIPDVNSDTGEITYEAESPDEAAFVIASRELGFEFFSRSQTSISLHEI 567

  Fly   940 MGQTEE-----YELLNILDFNNVRKRMSVILRRGDS-MVLYCKGADNVIYDRL--HGGQEDLKAR 996
            ...|.|     ||||::|:|::.|||||||:|..:: ::|..||||:|::.||  ||.|.:  ..
plant   568 DHMTGEKVDRVYELLHVLEFSSSRKRMSVIVRNPENRLLLLSKGADSVMFKRLAKHGRQNE--RE 630

  Fly   997 TQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEA-ALSMDSREQKLNAIYEEIESEMQLVG 1060
            |::|:.|:|..|||||.:..|.:.|..|..|......| .|..:.|:..::|..::||.::.|:|
plant   631 TKEHIKKYAEAGLRTLVITYREIDEDEYIVWEEEFLNAKTLVTEDRDALIDAAADKIEKDLILLG 695

  Fly  1061 VTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFI-VDGNSVEE 1124
            .||:|||||.|||..|..|..||:|||||||||.||||||||:|.||.:.:..:.: :|.:.:|.
plant   696 STAVEDKLQKGVPDCIEKLSQAGVKIWVLTGDKTETAINIGYACSLLREGMKQILVTLDSSDIEA 760

  Fly  1125 VEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAIS 1189
            :|||                |..:...:.:..|....|...|:||:|
plant   761 LEKQ----------------GDKEAVAKASFQSIKKQLREGMSQTAA------------------ 791

  Fly  1190 VVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPEL 1254
             ||   |...|:|         :.:||                      ||::|.||.:.|..:|
plant   792 -VT---DNSAKEN---------SEMFG----------------------LVIDGKSLTYALDSKL 821

  Fly  1255 ENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQE 1319
            |.:||::|.:|.:|||||.:|.|||||..|:|......|||||||||||.|::.|.|||||||.|
plant   822 EKEFLELAIRCNSVICCRSSPKQKALVTRLVKNGTGRTTLAIGDGANDVGMLQEADIGVGISGAE 886

  Fly  1320 GLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTV 1384
            |:|||::||::|||||:|||||||||.|.|.|:...:.||||||.||.....||..:..||.:..
plant   887 GMQAVMASDFAIAQFRFLERLLLVHGHWCYRRITLMICYFFYKNLAFGFTLFWYEAYASFSGKPA 951

  Fly  1385 FDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTS 1449
            ::..::|.||:|:|||||:|||||:||||.:..|::|.||..|:::.||:....:..:|:|..:|
plant   952 YNDWYMSCYNVFFTSLPVIALGVFDQDVSARLCLKYPLLYQEGVQNVLFSWERILGWMLNGVISS 1016

  Fly  1450 LVLFLIPYGVY------KDGVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTI 1508
            :::|.:.....      |||      .|.|:..||..:.:.::.....|:::..:|:|.:.|..|
plant  1017 MIIFFLTINTMATQAFRKDG------QVVDYSVLGVTMYSSVVWTVNCQMAISINYFTWIQHCFI 1075

  Fly  1509 WGSL-VWYFVLDYFYNYVIGGPYVGSLTQAMKDLTF-------------WVTMLITVMALVAPVL 1559
            |||: |||..|..:          |||........|             |:.:.:.|.:.:.|..
plant  1076 WGSIGVWYLFLVIY----------GSLPPTFSTTAFQVFVETSAPSPIYWLVLFLVVFSALLPYF 1130

  Fly  1560 AYKFYLLDVHPSLSDKIRQKSLKKIHSRASSDVRRTASSRRGRRSVRSGYAFAH 1613
            .|:.:.:...|...|.|       :..|.:.......::..|...|:..:...|
plant  1131 TYRAFQIKFRPMYHDII-------VEQRRTERTETAPNAVLGELPVQVEFTLHH 1177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8B	NP_731669.2	PhoLip_ATPase_N	195..260	CDD:292826	24/67 (36%)
		Cation_ATPase	891..985	CDD:289987	44/102 (43%)
		HAD_like	<1261..1324	CDD:304363	38/62 (61%)
		PhoLip_ATPase_C	1324..1571	CDD:292829	88/266 (33%)
AT3G27870	NP_189425.2	ATPase-Plipid	55..1149	CDD:273734	447/1420 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	235	1.000	Domainoid score	I621
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100089
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X168
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.730