| Sequence 1: | NP_731669.2 | Gene: | ATP8B / 41469 | FlyBaseID: | FBgn0037989 | Length: | 1726 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001354863.1 | Gene: | ATP8B2 / 57198 | HGNCID: | 13534 | Length: | 1209 | Species: | Homo sapiens |
| Alignment Length: | 1461 | Identity: | 669/1461 - (45%) |
|---|---|---|---|
| Similarity: | 855/1461 - (58%) | Gaps: | 332/1461 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 183 RRSSYYFSENERRIRANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVL 247
Fly 248 QLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLRNGKLVEAKWSEVQ 312
Fly 313 VGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFN 377
Fly 378 GEIICERPNNLLNKFDGTLIWRGQRFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGK 442
Fly 443 TQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGAT 507
Fly 508 VIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQ 572
Fly 573 IQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGA 637
Fly 638 IVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVR 702
Fly 703 YSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILH 767
Fly 768 DSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRS 832
Fly 833 KAFATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLLALCHTVMA 897
Fly 898 ETV-DGKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEVMGQTEEYELLNILDFNNVRKRM 961
Fly 962 SVILRRGDSMV-LYCKGADNVIYDRLHGGQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYN 1025
Fly 1026 DWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLT 1090
Fly 1091 GDKQETAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNS 1155
Fly 1156 DSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKG 1220
Fly 1221 SEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKALVVELI 1285
Fly 1286 KRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYY 1350
Fly 1351 RMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDK 1415
Fly 1416 NSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKDGVSANGFVVSDHMTLGAV 1480
Fly 1481 VATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVL----------DYFYNYVIGGPYVGSLT 1535
Fly 1536 QAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSL----KKIHSRASSDVRRTA 1596
Fly 1597 SSRRGRRSVRSGYAFAHQEGFGRLITSGKIM 1627 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| ATP8B | NP_731669.2 | PhoLip_ATPase_N | 195..260 | CDD:292826 | 42/64 (66%) |
| Cation_ATPase | 891..985 | CDD:289987 | 60/95 (63%) | ||
| HAD_like | <1261..1324 | CDD:304363 | 52/62 (84%) | ||
| PhoLip_ATPase_C | 1324..1571 | CDD:292829 | 125/256 (49%) | ||
| ATP8B2 | NP_001354863.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..36 | 5/13 (38%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1181..1209 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 478 | 1.000 | Domainoid score | I424 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0206 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H23226 | |
| Inparanoid | 1 | 1.050 | 1308 | 1.000 | Inparanoid score | I152 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S2398 |
| OMA | 1 | 1.010 | - | - | QHG53737 | |
| OrthoDB | 1 | 1.010 | - | - | D39163at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000076 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100089 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24092 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X168 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.790 | |||||