Protein Alignment ATP8B and atp9b

DIOPT Version :9

• Sequence 1: NP_731669.2
• Gene: ATP8B / 41469
• FlyBaseID: FBgn0037989
• Length: 1726
• Species: Drosophila melanogaster
• Sequence 2: XP_005170114.1
• Gene: atp9b / 568160
• ZFINID: ZDB-GENE-060503-583
• Length: 1136
• Species: Danio rerio
• Alignment Length: 1569
• Identity: 384/1569 - (24%)
• Similarity: 616/1569 - (39%)
• Gaps: 505/1569 - (32%)

  Fly    79 KNRRKRLHCNEDEDVKQPERRNSDLEGSPRACLAQPEGMNIGSSTQTIATPLMIGDSFYSLAPGG 143
            ||.||..:    .|..:|.|...:.|.|           |:..      .|||:.:..:.
Zfish    12 KNLRKTAY----YDASRPARYQIEDESS-----------NLDE------MPLMMSEEAFE----- 50

  Fly   144 GNPPPNKSDDQELYKQRDPSVTSESKS--------------------VPSLRRLSQIRRRRSSYY 188
                .::||.|.|.:.|   |:...:.                    |.:.||..:::.|  :.:
Zfish    51 ----NDESDYQTLPRAR---VSQRRRGLGWFLCGGWKVLCSSCCECLVHTCRRKKELKAR--TVW 106

  Fly   189 FSENERRIRANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAI 253
            ....|:          .:.||..|.||..||::.||:|..|.:||:...|.|||.:...|.:|::
Zfish   107 LGHPEK----------CEEKYPKNAIKNQKYNIVTFVPGVLYQQFKFFLNLYFLVVACSQFVPSL 161

  Fly   254 SSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNR-KSKTLRNGKLVEAKWSEVQVGDVI 317
            ......|...||..||.:|.|::|.|:::|...|.::|:: .||....|| |:.|.|::||||:|
Zfish   162 KIGYLYTYWAPLGFVLAVTMVREAVDEVRRCRRDKEMNSQLYSKLTVRGK-VQVKSSDIQVGDLI 225

  Fly   318 RLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAK---QCLTETIELGDRHDSLWNFNGE 379
            .::.||.:.||.:.|.|||..|.|||.|.:|||||:.|.:   .|......|||    |::.:..
Zfish   226 IVEKNQRIPADMIFLRTSEKTGSCFIRTDQLDGETDWKLRIGVACTQRLPALGD----LFSISAY 286

  Fly   380 IICERPNNLLNKFDGTLIWRGQRFALDNEKILLRGCVLRNTQWC---------YGVVVFAGVDTK 435
            :..::|...::.|:|.....      |.:..:.....:.||.|.         .|||::.|.:.:
Zfish   287 VYVQKPQLDIHSFEGNFTRE------DCDPPIHESLSIENTLWASTVVASGTVIGVVIYTGKEMR 345

  Fly   436 LMQNSGKTQFK----STGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHI 496
            .:.|:.:::.|    ...::||...:.:..|:..|.:.||        :|.:|       ||..
Zfish   346 SVMNTSQSKNKVGLLDLELNRLTKALFLAQVVLSVVMVAL--------QGFLG-------PWFR- 394

  Fly   497 IPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKA 561
                      .:...:|.|||      ::||||.|::::.:....::|..||.:  |.|    ..
Zfish   395 ----------NLFRFVVLFSY------IIPISLRVNLDMGKSAYGWMIMKDENI--PGT----VV 437

  Fly   562 RTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYG-DVIDLRTGELVEITEQQTIFQNS 625
            ||:|:.||||::.|:.:|||||||||.|.|.:..:...||| |.:|.....::     |:..|.|
Zfish   438 RTSTIPEELGRLVYLLTDKTGTLTQNEMVFKRLHLGTVSYGTDTMDEIQSHII-----QSYAQVS 497

  Fly   626 NTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMD 690
            :..:..|..|......|..|.|
Zfish   498 SAQSNGSSASSTPSRKPQPPAP------------------------------------------- 519

  Fly   691 ASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLS 755
                     .||.|..||..:|                                         :.
Zfish   520 ---------KVRKSVSSRIHEA-----------------------------------------VK 534

  Fly   756 RTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTS 820
            ..:.|..|..:::|:                                      .:..:.||:||.
Zfish   535 AIALCHNVTPVYESR--------------------------------------VNGANAEPESTE 561

  Fly   821 TLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVF 885
            .                                       :.||            ||:..:
Zfish   562 A---------------------------------------DQDF------------SDDNRT--- 572

  Fly   886 FRLLALCHTVMAETVDGKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEV-MGQTEEYELL 949
                                |||.||||.|||....:.|.....|...|:.::. .||...|.:|
Zfish   573 --------------------YQASSPDEVALVRWTESVGLTLVNRDLTSLQLKTPAGQILTYYIL 617

  Fly   950 NILDFNNVRKRMSVILRR---GDSMVLYCKGAD----NVIY--DRLHGGQEDLKARTQDHLNKFA 1005
            .|..|.:..|||.:|:|.   || :..|.||||    :::.  |.|           ::.....|
Zfish   618 QIFPFTSESKRMGIIVREEATGD-ITFYMKGADVAMASIVQYNDWL-----------EEECGNMA 670

  Fly  1006 GEGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQD 1070
            .||||||.:|::.|||:.|.|:.:|..:|.||:..|..|:.|:.|.:|.||:|:.:|.:||:||.
Zfish   671 REGLRTLVVAKKSLTEEQYQDFENRYNQAKLSIHDRNLKVAAVVESLEREMELLCLTGVEDQLQA 735

  Fly  1071 GVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKES 1135
            .|..::..|:|||||||:|||||.|||..|..|..|::.                .:.:..||
Zfish   736 DVRPTLELLRNAGIKIWMLTGDKLETATCIAKSSHLVSR----------------NQDIHVFK-- 782

  Fly  1136 IKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNK 1200
             .:.||             .::::        :.:||.::
Zfish   783 -PVSNR-------------GEAHL--------ELNAFRRK------------------------- 800

  Fly  1201 DNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQC 1265
                    .:|                          |||::|.||..||. ..|::|:::|.||
Zfish   801 --------HDC--------------------------ALVISGDSLEVCLR-YYEHEFVELACQC 830

  Fly  1266 KAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYS 1330
            .||:|||.:|.|||.:|.|:::.....|.|||||.||||||:||..|:||.|:||.||.|::|:|
Zfish   831 PAVVCCRCSPTQKAQIVRLLQQHTANRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFS 895

  Fly  1331 IAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNL 1395
            |.||:::.|||:||||.||.|.....::..::....:.....:|....|::..::....:..|..
Zfish   896 ITQFKHIGRLLMVHGRNSYKRSAALGQFVMHRGMIISTMQAVFSSIFYFASVPLYQGFLMVGYAT 960

  Fly  1396 FYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVY 1460
            .||..||.:| |.:|||..:.:|.:|.||....|....:.:.|:..||             ..:|
Zfish   961 IYTMFPVFSL-VLDQDVKPEMALLYPELYKDLTKGRSLSFKTFLIWVL-------------ISIY 1011

  Fly  1461 KDGVSANGFVV---SDHMTLGAVVATILIVDNTAQISL--YTSYWTVVNHVTIWGSLVWYFVLDY 1520
            :.|:...|.:|   .:.:.:.|:..|.||:.....::|  .|.:|.:|....|  ||..|.....
Zfish  1012 QGGILMYGALVLFDQEFVHVVAISFTALILTELLMVALTIRTWHWLMVVAQLI--SLACYLASLA 1074

  Fly  1521 FYNYVIGGPYVGSLT-QAMKDLTF-------WVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIR 1577
            |.|...|   :|.:| .|..||:|       |...:||:::.: |:...|:        |..|..
Zfish  1075 FLNEYFG---IGRVTLGAFLDLSFITTRVFLWKVCVITLVSCL-PLYIIKY--------LKRKFS 1127

  Fly  1578 QKSLKKIHS 1586
            ..|..|:.|
Zfish  1128 PPSYSKLSS 1136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8B	NP_731669.2	PhoLip_ATPase_N	195..260	CDD:292826	19/64 (30%)
		Cation_ATPase	891..985	CDD:289987	31/103 (30%)
		HAD_like	<1261..1324	CDD:304363	35/62 (56%)
		PhoLip_ATPase_C	1324..1571	CDD:292829	66/259 (25%)
atp9b	XP_005170114.1	PhoLip_ATPase_N	104..168	CDD:292826	20/73 (27%)
		ATPase-Plipid	117..1134	CDD:273734	357/1415 (25%)
		E1-E2_ATPase	173..413	CDD:278548	77/282 (27%)
		Cation_ATPase	567..649	CDD:289987	31/105 (30%)
		HAD_like	730..880	CDD:119389	70/249 (28%)
		PhoLip_ATPase_C	889..1128	CDD:292829	68/266 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.020