Protein Alignment ATP8B and atp10d

DIOPT Version :9

• Sequence 1: NP_731669.2
• Gene: ATP8B / 41469
• FlyBaseID: FBgn0037989
• Length: 1726
• Species: Drosophila melanogaster
• Sequence 2: XP_012818017.1
• Gene: atp10d / 549378
• XenbaseID: XB-GENE-1000388
• Length: 1373
• Species: Xenopus tropicalis
• Alignment Length: 1541
• Identity: 462/1541 - (29%)
• Similarity: 709/1541 - (46%)
• Gaps: 371/1541 - (24%)

  Fly   206 QFK---------YHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTT 261
            |||         |.||.|:|:||:|..|:|.||.|||.|.||.|||.|:.|..:|.:.:.....|
 Frog    59 QFKEEYEKLTKAYKNNRIQTTKYTLLNFIPRNLFEQFHRAANLYFLFLVFLNWVPLVEAFQKEIT 123

  Fly   262 AIPLIGVLTLTAVKDAYDDIQRHISDSQVNN-------RKSKTLRNGKLVEAKWSEVQVGDVIRL 319
            .:||:.|||:.|:||..:|.:::..|..:||       ||.|     |..|:.|.:|.||..|||
 Frog   124 MLPLVAVLTIIAIKDGLEDYRKYKLDKVINNIVTQVYCRKEK-----KYKESCWKDVNVGHFIRL 183

  Fly   320 DNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICER 384
            ..::.:.||.:||.:|:|:|:|.|||:.||||||||.:| :.:...:.|..|. ..|:|.|.||.
 Frog   184 QCDEIIPADMVLLHSSDPDGICHIETSSLDGETNLKQRQ-VVKGYSMDDEFDP-EKFSGRIQCEN 246

  Fly   385 PNNLLNKFDGTLIW-RGQRFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKST 448
            |.:.::.|.|.|.. ..::..|..:.:|||||::|||:...|:||:||.:||.|.|:...::|.:
 Frog   247 PTSDISSFKGFLDHPNKEKIGLSKQNLLLRGCIVRNTEAVVGIVVYAGHETKAMLNNSGPRYKRS 311

  Fly   449 GVDRLLNFIIIGIVLFLVSICALFAIGCAIW-----EGLI-------GQHFQLYLPWEHIIPKDY 501
            .::|.||..|:..||.|:::|...|||..:|     |..|       |||
 Frog   312 RLERRLNTDILWSVLLLIAMCLFGAIGHGLWLAGFPESPIFSIPEPGGQH--------------- 361

  Fly   502 IPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTL 566
              |...:.|..:|::..|:|..::|||||||:|:::..|.:.|..|.|.|...:::..:.|...:
 Frog   362 --TSPALAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQNDSEFYCEKSDSMIECRALNI 424

  Fly   567 NEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYG-----------DVIDLRTGELVEIT---- 616
            .|:|||:||||||||||||:|.|.|.:|||.|..|.           ...|:....|..:|
 Frog   425 AEDLGQVQYIFSDKTGTLTENKMVFRRCSIAGMEYSHEANARRLESYQESDMHGSNLCHVTCISQ 489

  Fly   617 -------EQQTIFQNSNTNN--------------RP------SPLSGAIVAPPAA--------PP 646
                   ||:....|.:.||              .|      ||:...:|..|..        |.
 Frog   490 SSVCKSKEQRKAASNKSLNNFAQGEDNDGASHPPNPRHVAFSSPMEKDVVPDPRLLSKFDQINPK 554

  Fly   647 PIILVHKAEVHAKKTSMVV-------TSSGEAQVLPDRPRSDIERSA---PPMDASEKRPGLKHV 701
            .:.:..:||..|.:||.:|       ..:.....||::||..:...:   .||.:.|:   :|.:
 Frog   555 SLYMSEEAEDTALETSYIVDFFLALAICNTVVVSLPNQPRQKVRMPSMVRTPMKSLEE---IKQM 616

  Fly   702 --RYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVK 764
              |:|.                              |::|.....||..|.....|...|
 Frog   617 FQRFSV------------------------------RKLSASSFTSGKDCPSENGSNFGS----- 646

  Fly   765 ILHDSQQTETHNMHHSSHNRKRLVKIRF----KKAPSTATLG-VVISQLEHHLDEEPQSTSTLST 824
                                    |:.|    |.|..||.|. ..|:.|        |:..:|::
 Frog   647 ------------------------KLSFFTRGKLASPTAELADKSINDL--------QAAGSLNS 679

  Fly   825 TKHHHHRSKAFATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLL 889
            |                          .:.......:|:|         ....||      ....
 Frog   680 T--------------------------AELEPEVLEQSNF---------VTACDE------LDKA 703

  Fly   890 ALCHTVMAETVDGKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEV--MGQTEEYELLNIL 952
            |.|          :|.|:|:||||||||.|||.:....::|||:.:|:|:  :|.. .:::|:||
 Frog   704 AAC----------ELCYEAESPDEAALVHAARAYNCTLQSRTPDQVTVELGFIGPL-TFQVLHIL 757

  Fly   953 DFNNVRKRMSVILRR--GDSMVLYCKGADNVIYDRLHGGQEDLKAR---------TQDHLNKFAG 1006
            .|::||||||||:|.  .:.:|:|.||||:.|.|.:....||.||.         ||.||:.:|.
 Frog   758 PFDSVRKRMSVIIRHPLTNKVVVYTKGADSAIMDLIAMTSEDNKAAMVKKNIQMLTQKHLDDYAK 822

  Fly  1007 EGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDG 1071
            .|||||.:|::.:|:..|.:|......|..|:|:||:.|......:|:::.|:|.|.|||:||:|
 Frog   823 GGLRTLCIAKKVMTDSEYAEWLQSHFLAETSIDNREEMLYESAVRLETKLTLLGATGIEDRLQEG 887

  Fly  1072 VPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESI 1136
            ||.:|.:|:.|||.||:|||||:|||:||.|:|:||                         :.|.
 Frog   888 VPDTIESLRKAGINIWMLTGDKEETAVNIAYACRLL-------------------------EHSD 927

  Fly  1137 KIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKD 1201
            |::|         ..:...:|....:::.:.:.                               |
 Frog   928 KLFN---------LSKHEKESCETLMNIMIDEI-------------------------------D 952

  Fly  1202 NKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCK 1266
            :.|.|      |.|...:..:.|          ..|.||::|.:|...:...|::|||.:..:|:
 Frog   953 SLGKP------NAFSSGQQDKSG----------LHFGLVIDGGTLEIAMHESLQSKFLQLTERCR 1001

  Fly  1267 AVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSI 1331
            ||||||.|||||:.||:|::.....:.|||||||||||||:.|.||||||||||:|||:|||:::
 Frog  1002 AVICCRATPLQKSKVVKLVRNNLQVMALAIGDGANDVSMIQVADIGVGISGQEGMQAVMSSDFAV 1066

  Fly  1332 AQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLF 1396
            :.|::|.:||||||.|.|.|:...:.||||||..|.....||..|||||...:.|...:.::||.
 Frog  1067 SHFKHLRKLLLVHGHWCYTRLANMILYFFYKNLMFVNLLFWYQFFCGFSGTAMTDFWMLILFNLL 1131

  Fly  1397 YTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPY---- 1457
            :||:|.:..|:.::|||.:.....|.||..|..|:.:....|..::|...:.||..|.|||
 Frog  1132 FTSVPPIIYGILDKDVSAETLTALPELYKSGQTSQAYRSSTFWVTILDAFYQSLACFFIPYFAYI 1196

  Fly  1458 ----GVYKDGVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVL 1518
                |:|..|    .|:::..:   .||...|::::.   ||...:|.|:.     .|:..||..
 Frog  1197 GSDLGIYSFG----NFLITSAL---FVVLLHLLIESK---SLTWIHWIVMG-----ASIAAYFAF 1246

  Fly  1519 DYFYNYVI------GGPYVGSLTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIR 1577
            ...:..|.      ..|| ..:...::|..|::..|:::...:.|....:.:...|.|:     .
 Frog  1247 SLAFGAVCINCNPPANPY-WIVQNHVRDPAFYLVCLLSIFIALLPRYVCRIFQGTVFPT-----P 1305

  Fly  1578 QKSLKKIHSRASSDVRRTASSRRGRRSVRSGYAFAHQEGFGRLITS 1623
            |...||:...:..:..|.....||.:|::...|..|.|..|..:|:
 Frog  1306 QLLAKKLDVMSPEERSRALKRWRGGQSLKGRKASQHLEPAGGSVTT 1351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8B	NP_731669.2	PhoLip_ATPase_N	195..260	CDD:292826	27/62 (44%)
		Cation_ATPase	891..985	CDD:289987	41/97 (42%)
		HAD_like	<1261..1324	CDD:304363	40/62 (65%)
		PhoLip_ATPase_C	1324..1571	CDD:292829	74/260 (28%)
atp10d	XP_012818017.1	P-type_ATPase_APLT_Dnf-like	73..1191	CDD:319770	420/1344 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	1	1.000	-	-		FOG0000076
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010