Protein Alignment ATP8B and atp9a

DIOPT Version :9

• Sequence 1: NP_731669.2
• Gene: ATP8B / 41469
• FlyBaseID: FBgn0037989
• Length: 1726
• Species: Drosophila melanogaster
• Sequence 2: NP_989232.1
• Gene: atp9a / 394841
• XenbaseID: XB-GENE-942215
• Length: 1045
• Species: Xenopus tropicalis
• Alignment Length: 1374
• Identity: 352/1374 - (25%)
• Similarity: 542/1374 - (39%)
• Gaps: 415/1374 - (30%)

  Fly   208 KYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTA-IPLIGVLTL 271
            :|..|.|...||:.|||||..|..||:...|.|||.|...|.:|.: .|.|:.|. :||..||.:
 Frog    52 RYPKNVINNQKYNFFTFLPGILYNQFKYFFNLYFLVLACTQFVPEM-RLGPLYTFWVPLGFVLLV 115

  Fly   272 TAVKDAYDDIQRHISDSQVNNRKSKTLRNGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSE 336
            |.:::|.::|:..:.|.:||::....|.|...|:.:.|.:||||::.::.||.:.||.:.|.|||
 Frog   116 TIIREAVEEIRCFVRDKEVNSQIYSKLTNRGTVKVRSSNIQVGDLVIVEKNQRIPADMIFLRTSE 180

  Fly   337 PNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQ 401
            .||.||:.|.:|||||:.|.:..:..|..|....| |......|..|.||..::.|.||.. |..
 Frog   181 KNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAAD-LLQIRSYIYAEEPNIDIHNFAGTFT-RED 243

  Fly   402 RFALDNEKILLRGCVLRNTQWC---------YGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFI 457
            .....||.:     .:.||.|.         .||||:.|.:.:.:.|:...:.|....|..||.:
 Frog   244 SDPPTNESL-----SIENTLWASTVIASGTVVGVVVYTGREQRSVMNTSNPRSKIGLFDLELNCL 303

  Fly   458 --IIGIVLFLVSICALFAIGCAIWEGLIGQHF--QLYLPWEHIIPKDYIPTGATVIGLLVFFSYA 518
              |:...|.:||: .:.|:          |||  :.||               .:|..|:.||
 Frog   304 TKILFSALIVVSL-VMVAL----------QHFAGRWYL---------------QIIRFLLLFS-- 340

  Fly   519 IVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGT 583
                :::||||.|::::.:.|.|:||..|.::  |.|    ..|.:|:.|:||:|.|:.:|||||
 Frog   341 ----SIIPISLRVNLDMGKIVYSWLIRRDPKI--PGT----VVRASTIPEQLGRISYLLTDKTGT 395

  Fly   584 LTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPI 648
            ||||.|.|.:..:...:||      |..:.|:  |..||              ::...||..||
 Frog   396 LTQNEMVFKRLHLGTVAYG------TDSMDEV--QSHIF--------------SVYTQPAQDPP- 437

  Fly   649 ILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDAD 713
                                                       |:|....| ||.:..||..:|
 Frog   438 -------------------------------------------SQKGMSTK-VRKTMSSRVYEA- 457

  Fly   714 AGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMH 778
                                                    :...:.|              ||:
 Frog   458 ----------------------------------------VKAIALC--------------HNV- 467

  Fly   779 HSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSP 843
                            .||..:.||.        |:
 Frog   468 ----------------TPSYESNGVT--------DQ----------------------------- 479

  Fly   844 HRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLLALCHTVMAETVDGKLEYQA 908
                                        .:|.|..|:...|                     |||
 Frog   480 ----------------------------AEAERQFEDSCRV---------------------YQA 495

  Fly   909 QSPDEAALVSAARNFGFVFRTRTPNSITIEV-MGQTEEYELLNILDFNNVRKRMSVILRRGDS-- 970
            .||||.|||....:.|.....|..:|:.:.. .||...:.:|.|..|....|||.:|:|...:
 Frog   496 SSPDEVALVQWTESVGLSLVGRDQSSMQLRTPSGQILNFSILQIFPFTYESKRMGIIVREDSTGE 560

  Fly   971 MVLYCKGADNVIYDRLHGGQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEAA 1035
            :..|.||||.|:     .|........::.....|.||||.|.:|::.|||:.|.|:.:|..:|.
 Frog   561 ITFYMKGADVVM-----AGIVQYNDWLEEECGNMAREGLRVLVVAKKSLTEEQYQDFEARYVQAK 620

  Fly  1036 LSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINI 1100
            ||:..|..|:..:.|.:|.||:|:.:|.:||:||..|..::..|:|||:|:|:|||||.|||...
 Frog   621 LSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLEMLRNAGMKVWMLTGDKLETATCT 685

  Fly  1101 GYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVT 1165
            ..:..|:|.. .|:.:                         |||
 Frog   686 AKNAHLVTRN-QDIHV-------------------------FRP--------------------- 703

  Fly  1166 MTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIV 1230
            :|.......|.|              .||  .|:          :|
 Frog   704 VTNRGEAHLELN--------------AFR--RKH----------DC------------------- 723

  Fly  1231 VDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLA 1295
                   |||::|.||..||. ..|.:|:::|.||.||:|||..|.|||.:|.|::.....:|.|
 Frog   724 -------ALVISGDSLEVCLK-YYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCA 780

  Fly  1296 IGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFF 1360
            :|||.||||||:.|..|||:.|:||.||.|::|:|:.||::|.|||:||||.||.|.....::..
 Frog   781 VGDGGNDVSMIQEADCGVGVEGKEGKQASLAADFSVTQFKHLGRLLMVHGRNSYKRSAGLSQFVI 845

  Fly  1361 YKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYT 1425
            :::...:.....:|....|::..::....|..|:..||..||.:| |.::||..:.::.:|.||.
 Frog   846 HRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYK 909

  Fly  1426 PGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKDGVSANGFVV---SDHMTLGAVVATILIV 1487
            ..||....:.:.|:..||             ..:|:..:...|.::   |:.:.:.|:..|.||:
 Frog   910 DLLKGRPLSYKTFLIWVL-------------ISIYQGSIIMYGALLLFESEFVHIVAISFTSLIL 961

  Fly  1488 DNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYNYVIGGPYVGSLTQAMKDLTFWVTMLITVM 1552
            .....::|....|..:..|....||..|.....|.:..|...::.:|:...|     ||.:..|.
 Frog   962 TELLMVALTIQTWHWLMIVAELLSLSCYVASLVFLHEFIDVYFIATLSFLWK-----VTSITLVS 1021

  Fly  1553 ALVAPVLAY 1561
            .|...||.|
 Frog  1022 CLPLYVLKY 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8B	NP_731669.2	PhoLip_ATPase_N	195..260	CDD:292826	22/51 (43%)
		Cation_ATPase	891..985	CDD:289987	29/96 (30%)
		HAD_like	<1261..1324	CDD:304363	33/62 (53%)
		PhoLip_ATPase_C	1324..1571	CDD:292829	60/241 (25%)
atp9a	NP_989232.1	P-type_ATPase_APLT_Neo1-like	55..965	CDD:319841	334/1299 (26%)
		Cation_ATPase	463..571	CDD:372530	40/224 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010