Protein Alignment ATP8B and atp11c

DIOPT Version :9

• Sequence 1: NP_731669.2
• Gene: ATP8B / 41469
• FlyBaseID: FBgn0037989
• Length: 1726
• Species: Drosophila melanogaster
• Sequence 2: XP_004917005.2
• Gene: atp11c / 100498300
• XenbaseID: XB-GENE-976439
• Length: 1149
• Species: Xenopus tropicalis
• Alignment Length: 1436
• Identity: 399/1436 - (27%)
• Similarity: 645/1436 - (44%)
• Gaps: 395/1436 - (27%)

  Fly   198 ANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTA 262
            |::.:...|.|:.:|.|.:|||:::.|:|.||.|||:|:||||||.:.::|.| ..:..:|||:.
 Frog    29 ASETDAYIQPKFCDNRIVSSKYTIWNFIPKNLFEQFRRIANFYFLIIFLIQAI-VDTPTSPVTSG 92

  Fly   263 IPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLRNGKLVEAKWSEVQVGDVIRLDNNQFVAA 327
            :||..|:|:||:|..|:|..||.:|.:||......:...|.|:.:..:::|||::.:.:|:....
 Frog    93 LPLFFVITVTAIKQGYEDWLRHRADHEVNKSTVYVIEGSKCVKKESEKIKVGDIVEVRDNETFPC 157

  Fly   328 DTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKF 392
            |.::||||..:|.|.:.||.||||:|.|....:.||..|. .::.|..|:..|.||:|...|.||
 Frog   158 DLVMLSTSCRDGTCTVTTASLDGESNFKTYHAVPETAILA-TYEDLNAFSATIECEQPQPDLYKF 221

  Fly   393 DGTL-IWRGQRF---ALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQN-SGKTQFKSTGVDR 452
            .|.: :...|..   :|..|.:||:|..|:||:..|||.|:.|::||:..| .||:| |.:.|::
 Frog   222 HGRIDVNTNQDVKARSLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQ-KRSAVEK 285

  Fly   453 LLNFIIIGIVLFLVS---ICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGATVIGLLVF 514
            .:|..:|..:..|||   ||.....   :|:......    .||.:...:........:.....|
 Frog   286 SINAFLIVYLCILVSKATICTSLKY---LWQSNPAND----EPWYNEKTRKEKEAFKILKMFTDF 343

  Fly   515 FSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSD 579
            .|:.::.|.::|:|:||:||:.:|:.||.|.||.||:....|..|...|:.|||||||::|:|:|
 Frog   344 LSFMVLFNFIIPVSMYVTVEMQKFLGSFFIAWDMEMFDEEINEGALVNTSDLNEELGQVEYVFTD 408

  Fly   580 KTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAA 644
            ||||||:|.|.|.:|.|:|..|                       :||
 Frog   409 KTGTLTENKMEFIECCIDGHKY-----------------------ANT----------------- 433

  Fly   645 PPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRS 709
                                                                             
 Frog   434 ----------------------------------------------------------------- 433

  Fly   710 QDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTET 774
                        |...|||         ::.|....|
 Frog   434 ------------DAMDGLS---------LTDGLAYFG---------------------------- 449

  Fly   775 HNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNW 839
                                                                             
 Frog   450 ----------------------------------------------------------------- 449

  Fly   840 SSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLLALCHTVMAET---VD 901
                                                ::.::...:|.|.|.|||||..:.   .|
 Frog   450 ------------------------------------KASQDLEELFLRALCLCHTVQMKEECHTD 478

  Fly   902 G-------KLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIE-VMGQTEEYELLNILDFNNVR 958
            |       ...|.:.||||.|||:.|:.:||.:.....|.:::| ...:.|.|:||::|:|:.||
 Frog   479 GPSFSSTDNCAYISSSPDEIALVTGAKRYGFTYMGTENNVMSVENQKNEIERYQLLHVLNFDPVR 543

  Fly   959 KRMSVILR-RGDSMVLYCKGADNVIYDRLHGGQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQ 1022
            :||||::: :...:.|:|||||:.::.|:   ..|...|.:.|:.|.|.:|.|||.:|.:.::::
 Frog   544 RRMSVLVKAKTGKIFLFCKGADSSMFPRV---ARDQVQRIKVHVEKNALDGYRTLCVAFKEVSQE 605

  Fly  1023 YYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIW 1087
            .|.:...:.:||.|::..||::|..:|::||::|.|:|.||:||:||:...::|..|..||:|:|
 Frog   606 LYENINKQLEEAKLALQDREERLAKVYDDIEADMHLLGATAVEDRLQEQAAETIEALHAAGMKVW 670

  Fly  1088 VLTGDKQETAINIGYSCQLL--TDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPF 1150
            ||||||.|||.:..|:|:|.  ..||.::...|   :||.|::..:.:|.:..|:|
 Frog   671 VLTGDKLETAKSTCYACRLFQSNTELLELTTKD---LEEYERKEDRLQELLMEYHR--------- 723

  Fly  1151 DRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLF 1215
                                ..:||.         |.:              |||.:.:...|
 Frog   724 --------------------KLVQEA---------PKL--------------KGGANRSWTGN-- 743

  Fly  1216 GDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKAL 1280
            .|.....||.|.|::::.|              |.|...:|.||.|..:|.||:|||:.|||||.
 Frog   744 QDHGLIIDGATLSLILNSN--------------CSSSHYKNIFLQICQKCSAVLCCRMAPLQKAQ 794

  Fly  1281 VVELIKRAKNA-VTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVH 1344
            :|:::|..|.: :||::||||||||||..||:|:||.|:||.||..||||::.:|::|.:|||.|
 Frog   795 IVKMVKNTKGSPITLSVGDGANDVSMILEAHVGIGIKGKEGRQAARSSDYAVPKFKHLRKLLLAH 859

  Fly  1345 GRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFE 1409
            |...|.|:...::||||||..|.|....|..|||||.|.::|..::::||:.:||:|:||..:.|
 Frog   860 GHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSMPILAYSLLE 924

  Fly  1410 QDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVY----KDGVSANGFV 1470
            |.::.:.....|:||.....:.:.....|:|..|.|||..||.|   :|||    ...:..||.|
 Frog   925 QRINIEILSSNPKLYMRISDNAMLQWGPFLYWTLLGAFEGLVFF---FGVYFLFQNPALEGNGQV 986

  Fly  1471 VSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYNYVIGGPYVGS-- 1533
            .. :.:.|.:|.|||:...|.:::|.|.|||.:||:.|||||.:|.:...|:..:| .|::..
 Frog   987 YG-NWSFGTMVFTILVFTVTLKLALDTRYWTWMNHLAIWGSLAFYVIFSLFWGGII-WPFLKQQR 1049

  Fly  1534 ----LTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSLK----KIHSRASS 1590
                .:..:..::.|:.:::.:...:.|.:..              |..|:||    |.|..:|.
 Frog  1050 MYFVFSHILTSVSIWLGIILLIFVSLYPEIVL--------------ILVKNLKTANQKEHQLSSC 1100

  Fly  1591 DVRRTA 1596
            .::..|
 Frog  1101 SLKPPA 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8B	NP_731669.2	PhoLip_ATPase_N	195..260	CDD:292826	25/61 (41%)
		Cation_ATPase	891..985	CDD:289987	38/105 (36%)
		HAD_like	<1261..1324	CDD:304363	36/63 (57%)
		PhoLip_ATPase_C	1324..1571	CDD:292829	80/256 (31%)
atp11c	XP_004917005.2	P-type_ATPase_APLT_Dnf-like	42..971	CDD:319770	358/1270 (28%)
		7TMR-DISM_7TM	954..>1071	CDD:377898	37/121 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920