Protein Alignment ATP8B and atp11a

DIOPT Version :9

• Sequence 1: NP_731669.2
• Gene: ATP8B / 41469
• FlyBaseID: FBgn0037989
• Length: 1726
• Species: Drosophila melanogaster
• Sequence 2: XP_031752894.1
• Gene: atp11a / 100485769
• XenbaseID: XB-GENE-1010941
• Length: 1193
• Species: Xenopus tropicalis
• Alignment Length: 1460
• Identity: 402/1460 - (27%)
• Similarity: 649/1460 - (44%)
• Gaps: 404/1460 - (27%)

  Fly   178 SQIRRRRSSYYFSE----NERRIRANDK------EFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQ 232
            |.:||..:.|...|    :.|.|....|      |.....:|.:|.|.:|||:.:.|:|.||.||
 Frog     4 SALRRLINRYCAGEENWVDNRTIYVGHKQPPPGTEAYIPQRYPDNRIVSSKYTFWNFVPKNLFEQ 68

  Fly   233 FQRLANFYFLCLLVLQLIPAISSLT-PVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSK 296
            |:|:||||||.:.::|||  |.:.| |||:.:||..|:|:||:|..|:|..||.:|:.:|.....
 Frog    69 FRRIANFYFLIIFLVQLI--IDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQYSVH 131

  Fly   297 TLRNGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLT 361
            .:::||||..:..:::|||::.:..::....|.:.||:|..:|.||:.||.||||::.|....:.
 Frog   132 VVQHGKLVRTQSRKLRVGDIVMVREDEAFPCDLVFLSSSREDGTCFVTTASLDGESSHKTYYAIN 196

  Fly   362 ETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTL---------IWRGQRFALDNEKILLRGCVL 417
            :|... ...:.:...:..|.||:|...|.||.|.:         :.|    .|.:|.:||||..|
 Frog   197 DTKSF-HHEEEMEGLHATIECEQPQPDLYKFVGRINIYNEADEPVAR----PLGSENLLLRGATL 256

  Fly   418 RNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGL 482
            :||:..:||.::.|::||:..|......|.:.|::.:|..:|..:..|:|...:..:...||:..
 Frog   257 KNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYIWQSD 321

  Fly   483 IGQHFQLYLPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWD 547
            ..:.    .||.:............:.....|.::.::.|.::|:|:||:||:.:|:.|:.|:||
 Frog   322 SSRD----EPWYNQKTDSERQKNKFLGAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFISWD 382

  Fly   548 EEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGEL 612
            |||:..||.......|:.|||||||::|||:|||||||:|.|.|.:|.|.|..|
 Frog   383 EEMFDETTGEGPIVNTSDLNEELGQVEYIFTDKTGTLTENNMEFVECCIEGHVY----------- 436

  Fly   613 VEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDR 677
                                            .|.:|.                   ..|:|||.
 Frog   437 --------------------------------IPHVIC-------------------NGQILPDC 450

  Fly   678 PRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGF 742
            ...|:..|:|                                   |:||
 Frog   451 MGIDMIDSSP-----------------------------------GAGG---------------- 464

  Fly   743 KRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQ 807
                                                                             
 Frog   465 ----------------------------------------------------------------- 464

  Fly   808 LEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLL 872
                                                                             
 Frog   465 ----------------------------------------------------------------- 464

  Fly   873 DAVRSDEEHSHVFFRLLALCHTVMA---ETVDGKLE---------YQAQSPDEAALVSAARNFGF 925
                  :|...:|||.|.|||||..   :.:||:.:         |.:.||||.|||...:..|:
 Frog   465 ------KEREELFFRALCLCHTVQVKDEDHIDGEKKSSHSGRSSVYISSSPDEVALVEGVQRLGY 523

  Fly   926 VFRTRTPNSITI-EVMGQTEEYELLNILDFNNVRKRMSVILR--RGDSMVLYCKGADNVIYDRLH 987
            .|.....|.:.| ......|::|||.:|.|::||:|||||:|  .|| :.|:|||||:.|:.|:.
 Frog   524 TFLRVKDNYMEICNRENDIEKFELLQVLTFDSVRRRMSVIVRSSTGD-IYLFCKGADSSIFPRVR 587

  Fly   988 GGQED-LKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSR-QQEAALSMDSREQKLNAIYE 1050
            .|:.| ::||.:    :.|.||||||.:|.::.::..| :|.:: .::|.|::..||:||...||
 Frog   588 EGKVDQIRARVE----RNAVEGLRTLCVAYKKFSQDEY-EWANKLLKDAQLALQDREKKLAEAYE 647

  Fly  1051 EIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVF 1115
            :||.::.|:|.||:||:||:....:|.:||.||||:|||||||.|||....|:|:|
 Frog   648 QIEQDLILLGATAVEDRLQEKAADTIESLQKAGIKVWVLTGDKMETASATCYACKL--------- 703

  Fly  1116 IVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMD---PLSVTMTQTSAFMQETN 1177
                         .|:..:.:::..:          |:...|..|   .||.|:.:.|
 Frog   704 -------------FRRNTQLLELTTK----------RIEEQSLHDVLFELSRTVLRHS------- 738

  Fly  1178 LPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVN 1242
                                         :|...:|..|.....:|             :.|:::
 Frog   739 -----------------------------ESLTRDNFSGFSTDFQD-------------YGLIID 761

  Fly  1243 GHSLVHCLSPELENK-------FLDIASQCKAVICCRVTPLQKALVVELIKRAK-NAVTLAIGDG 1299
            |.:|...:.|..:..       ||:|...|.||:|||:.|||||.:|:|||.:: :.:|||:|||
 Frog   762 GATLSLIMKPREDGSSTNYREVFLEICRNCSAVLCCRMAPLQKAQIVKLIKSSREHPITLAVGDG 826

  Fly  1300 ANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNF 1364
            |||||||..||:|:|:.|:||.||..:|||:|.:|::|:|:||:||.:.|.|:.:.::||||||.
 Frog   827 ANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKRMLLIHGHYYYVRISELVQYFFYKNV 891

  Fly  1365 AFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLK 1429
            .|......|..|||||.|.::|..::::||:.:||||:|...:.||.||.......|.||....|
 Frog   892 CFIFPQFLYQFFCGFSQQPLYDTAYLTLYNISFTSLPILLYSLIEQHVSVDVLKRDPTLYRDIAK 956

  Fly  1430 SELFNIREFIYSVLHGAFTSLVLFLIPYGVYKDG-VSANGFVVSDHMTLGAVVATILIVDNTAQI 1493
            :.|...|.|||....|.|.:.|.|...|.:|.:. |::||.::. :.|.|.:|.|:|:...|.::
 Frog   957 NALLRWRLFIYWTFLGLFDAAVFFFGAYFLYDNATVTSNGQMLG-NWTFGTLVFTVLVFTVTFKL 1020

  Fly  1494 SLYTSYWTVVNHVTIWGSLVWYFVLDYFYNYVIGGPYVG------SLTQAMKDLTFWVTMLITVM 1552
            :|.|.|||.:||..|||||::|.:....:..:| .|::.      ...|.:.....|:.:::.::
 Frog  1021 ALDTHYWTWINHFVIWGSLLFYIIFSLLWGGII-WPFLNYQRMYYVFIQMLSSGPAWLGIVLLII 1084

  Fly  1553 ALVAPVLAYKFYLLDVHPSLSDKIRQKSLK 1582
            ..:.|.:..|.....:.|:.:::|:..|::
 Frog  1085 VSLLPDVLRKVICRQLWPTATERIQDASMR 1114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP8B	NP_731669.2	PhoLip_ATPase_N	195..260	CDD:292826	29/71 (41%)
		Cation_ATPase	891..985	CDD:289987	42/108 (39%)
		HAD_like	<1261..1324	CDD:304363	37/63 (59%)
		PhoLip_ATPase_C	1324..1571	CDD:292829	82/253 (32%)
atp11a	XP_031752894.1	P-type_ATPase_APLT_Dnf-like	47..983	CDD:319770	359/1282 (28%)
		RDD	<965..1061	CDD:412544	33/97 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010