Protein Alignment CG14736 and nphs2

DIOPT Version :10

• Sequence 1: NP_731666.2
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_001018155.2
• Gene: nphs2 / 557914
• ZFINID: ZDB-GENE-051102-2
• Length: 391
• Species: Danio rerio
• Alignment Length: 339
• Identity: 112/339 - (33%)
• Similarity: 174/339 - (51%)
• Gaps: 57/339 - (16%)

  Fly     6 ERKDAATNS----EMSKHDQKIPPKEFKRPSADGGPRPPPSRYIQTSE-DNKDSTFEKVA----- 60
            |||..|..|    |..|..:|:...|.:..:.|       ::.|.:|. .|.||..|::.
Zfish    34 ERKTKAAKSVKLQEPHKRKEKLVTTEEEEEAKD-------AQIISSSTVVNVDSVRERIKEEREE 91

  Fly    61 ------------------IGICWFL--------VIITFPFSMCCCLTIVPEYSRMIILRLGR-LR 98
                              :|:|..|        ||:..|.|:..|:.||.|:.|.:..|||. |:
Zfish    92 LLALLETEGPGEGLKKKYLGVCELLLIVLVLSVVILFLPISVWFCVKIVREHERAVKFRLGHLLK 156

  Fly    99 KGLRGPGLVFILPCIDETHRVDMRTDVTNVRPQDVLTKDSVTITVNAVVYYCI------YSPIDS 157
            |..|||||:|.||.:|..|.||:|..:..:.|..|:|||.|...|.||.||.|      ||   |
Zfish   157 KRPRGPGLMFYLPFLDVCHIVDIRLQILKIPPHMVVTKDLVCTEVTAVCYYRIENVSVCYS---S 218

  Fly   158 IIQVDDAKQATQLISQVTLRNIVGSKTLNVLLTSRQQLSREIQQAVAGITYRWGVRVERVDVMDI 222
            ...:.|..||   ::||::|.|:.....|.:|..|:::::|||..:...|.|||::||:.::.:|
Zfish   219 FASIPDVMQA---LTQVSVREILAHHAFNDILLDRKRIAQEIQVTLDSGTCRWGIKVEKAEIEEI 280

  Fly   223 TLPTSLERSLASEAEAVREARAKIILAEGELKASKALKEASDVMSENKITLQLRHLQILSSIASE 287
            .||..|:.:.|.||||.|:|:.|:|.||||..|.:|||.:.:.:|.:.:.:.||.||:|.|:.||
Zfish   281 NLPPELQHNFAVEAEARRQAQVKVIAAEGEKAACEALKASVESVSGSPLVMHLRLLQLLHSLRSE 345

  Fly   288 RRVRIIYPIPLEIM 301
            :.. ::..||.:::
Zfish   346 QPA-VVLNIPPDVL 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14736	NP_731666.2	SPFH_like	100..305	CDD:473137	79/208 (38%)
nphs2	NP_001018155.2	SPFH_like	134..356	CDD:473137	89/228 (39%)