DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14736 and Stoml1

DIOPT Version :9

Sequence 1:	NP_001287293.1	Gene:	CG14736 / 41466	FlyBaseID:	FBgn0037986	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_001292167.1	Gene:	Stoml1 / 300748	RGDID:	1559463	Length:	398	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	80/279 - (28%)
Similarity:	126/279 - (45%)	Gaps:	59/279 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 WFLVIITFPFSMCCCLTIVPEYSRMIILRLGRLRKGLRGPGLVFILPCIDETHRVDMRTDVTNVR 129
            :.|:::|||.|....|.|||.|.|||:.||||:|.. :|||:|.:||.||...|||:||...||.
  Rat    64 FLLLLLTFPISGWFALKIVPTYERMIVFRLGRIRNP-QGPGMVLLLPFIDSFQRVDLRTRAFNVP 127

  Fly   130 PQDVLTKDSVTITVNAVVYYCIYSPIDSIIQVDDAKQATQLISQVTLRNIVGSKTLNVLLTSRQQ 194
            |..:.:||...::|.|.|.:.|:.|:.|::.|.|...||::.:...:...:..:.|..:...:.:
  Rat   128 PCKLASKDGAVLSVGADVQFRIWDPVLSVMAVKDLNAATRMTAHNAMTKALLRRPLQEIQMEKLK 192

  Fly   195 LSREIQQAVAGITYRWGVRVERVDVMDITLPTSLERSLASEAEAVREARAKIILAEGELKASKAL 259
            :..::...:..:|..||:.|:||:             ||.||                     .|
  Rat   193 IGDQLLLEINDVTRAWGLEVDRVE-------------LAVEA---------------------VL 223

  Fly   260 KEASDVMSENKI--TLQLRHLQIL-SSIASERRVRIIYPIP----LEI---MEPFMSGKEGQKKD 314
            :...|.::...:  |||...|..| .|:.|..||    |.|    ||:   :||          .
  Rat   224 QPPQDSLAVPSLDSTLQQLALHFLGGSMTSVGRV----PSPGSDTLEMINEVEP----------P 274

  Fly   315 GGGGGGGGKETKKEDVAGG 333
            ....|.|.:.:.|:.||.|
  Rat   275 ASRAGAGTEPSPKQPVAEG 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14736	NP_001287293.1	PHB	78..225	CDD:214581	48/146 (33%)
CG14736	NP_001287293.1	SPFH_like	100..305	CDD:302763	56/214 (26%)
Stoml1	NP_001292167.1	PHB	77..217	CDD:214581	48/153 (31%)
		SPFH_SLP-1	94..224	CDD:259814	42/164 (26%)
		SCP2	304..395	CDD:280250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062075at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820