Protein Alignment CG14736 and STOM

DIOPT Version :9

• Sequence 1: NP_001287293.1
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_004090.4
• Gene: STOM / 2040
• HGNCID: 3383
• Length: 288
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 127/289 - (43%)
• Similarity: 195/289 - (67%)
• Gaps: 18/289 - (6%)

  Fly    29 KRPSADGGPRPPPSRYIQTSEDNKDSTFEKVAIGIC-WFLV-------IITFPFSMCCCLTIVPE 85
            ||.:.|...:..|..:       |||..:  .:|.| |.||       :||||.|:..|:.|:.|
Human     4 KRHTRDSEAQRLPDSF-------KDSPSK--GLGPCGWILVAFSFLFTVITFPISIWMCIKIIKE 59

  Fly    86 YSRMIILRLGR-LRKGLRGPGLVFILPCIDETHRVDMRTDVTNVRPQDVLTKDSVTITVNAVVYY 149
            |.|.||.|||| |:.|.:||||.|||||.|...:|||||...::.||::||||||||:|:.||||
Human    60 YERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEILTKDSVTISVDGVVYY 124

  Fly   150 CIYSPIDSIIQVDDAKQATQLISQVTLRNIVGSKTLNVLLTSRQQLSREIQQAVAGITYRWGVRV 214
            .:.:...::..:.:|..||:|::|.||||::|:|.|:.:|:.|::::..:|..:...|..||::|
Human   125 RVQNATLAVANITNADSATRLLAQTTLRNVLGTKNLSQILSDREEIAHNMQSTLDDATDAWGIKV 189

  Fly   215 ERVDVMDITLPTSLERSLASEAEAVREARAKIILAEGELKASKALKEASDVMSENKITLQLRHLQ 279
            |||::.|:.||..|:|::|:||||.||||||:|.||||:.||:||||||.|::|:...||||:||
Human   190 ERVEIKDVKLPVQLQRAMAAEAEASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQ 254

  Fly   280 ILSSIASERRVRIIYPIPLEIMEPFMSGK 308
            .|::||:|:...|::|:|:::::..:..|
Human   255 TLTTIAAEKNSTIVFPLPIDMLQGIIGAK 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14736	NP_001287293.1	PHB	78..225	CDD:214581	66/147 (45%)
		SPFH_like	100..305	CDD:302763	97/204 (48%)
STOM	NP_004090.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		5/24 (21%)
		SPFH_stomatin	73..274	CDD:259801	97/200 (49%)
		Required for homooligomerization	265..273		2/7 (29%)
		Required for lipid raft association	267..269		1/1 (100%)
		Interaction with LANCL1. /evidence=ECO:0000269|PubMed:9512664	273..287		1/11 (9%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062075at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820