Protein Alignment CG14736 and unc-24

DIOPT Version :10

• Sequence 1: NP_731666.2
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_001355386.1
• Gene: unc-24 / 177594
• WormBaseID: WBGene00006761
• Length: 443
• Species: Caenorhabditis elegans
• Alignment Length: 323
• Identity: 82/323 - (25%)
• Similarity: 138/323 - (42%)
• Gaps: 49/323 - (15%)

  Fly    45 IQTSEDNKD-STFEKVAIGICWFLVIITFPFSMCCCLTIVPEYSRMIILRLGRLRKGLRGPGLVF 108
            :...:|.|. |..|.:...:.:..|::|.|.|:...|..:....::::|||||.:| .||||:..
 Worm    95 VNMEDDIKPLSAIELLIFCVSFLFVVMTMPLSLLFALKFISTSEKLVVLRLGRAQK-TRGPGITL 158

  Fly   109 ILPCIDETHRVDMRTDVTNVRPQDVLTKDSVTITVNAVVYYCIYSPIDSIIQVDDAKQATQLISQ 173
            ::||||.||:|.|.....||.|..::|.|...:.:.|.|:..|..||.::..|.|...:.:.::.
 Worm   159 VIPCIDTTHKVTMSITAFNVPPLQIITTDRGLVELGATVFLKIRDPIAAVCGVQDRNASVRTLAN 223

  Fly   174 VTLRNIVGSKTLNVLLTSRQQLSREIQQAVAGITYRWGVRVERVDVMDITLPTSLER----SLAS 234
            ..|...:..|             |.....:...|.::||.:..|::.|:.:....|.    :|:|
 Worm   224 TMLYRYISKK-------------RICDDELGSFTCQFGVEITDVEISDVKIVKEGENMGMSALSS 275

  Fly   235 EAEA------------VREARAKIILAEGELKASKALKEASDVMS----------ENKITLQLRH 277
            .|::            |.|..||...||.:.|.:..|.:.|||.|          .|..::.:.|
 Worm   276 VAKSDAGQQLWQVIGPVFEDFAKECAAEEKAKENAPLVDLSDVPSTSAAGTSTDTPNIPSIDIDH 340

  Fly   278 LQILSSIA-SERRVRII---YPIPLEIMEPFMSGKEGQKKDGGGGGGGGKETKKEDVAGGSKE 336
            |..::|:| .|..||:|   :.|..:.:||...    ..|.|.|....|.....:.|...|.|
 Worm   341 LISVASLAMDEHLVRLIGRVFQINCKDIEPICI----DLKHGSGSAYKGTSLNPDVVFETSLE 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14736	NP_731666.2	SPFH_like	100..305	CDD:473137	60/234 (26%)
unc-24	NP_001355386.1	SPFH_like	146..263	CDD:473137	35/130 (27%)
		SCP2	357..439	CDD:442486	11/47 (23%)