Protein Alignment CG14736 and Nphs2

DIOPT Version :10

• Sequence 1: NP_731666.2
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_569723.1
• Gene: Nphs2 / 170484
• MGIID: 2157018
• Length: 385
• Species: Mus musculus
• Alignment Length: 315
• Identity: 102/315 - (32%)
• Similarity: 175/315 - (55%)
• Gaps: 32/315 - (10%)

  Fly    30 RPSADGGPRPPPSRYIQTSED-----NKDSTFEKVA---------------IGIC-WFLV----- 68
            |.:..|.||.|.:.......|     .::.| |.||               :|.| |.||
Mouse    50 RTATRGEPRAPAATATVVDVDEVRGPGEEGT-EVVALLESERPEEGIKPSGLGACEWLLVLASLI 113

  Fly    69 --IITFPFSMCCCLTIVPEYSRMIILRLGRLRKG-LRGPGLVFILPCIDETHRVDMRTDVTNVRP 130
              |:|||||:..|:.:|.||.|:||.|||.|..| .:||||.|.|||:|..|:||:|.....:..
Mouse   114 FIIMTFPFSIWFCIKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPF 178

  Fly   131 QDVLTKDSVTITVNAVVYYCIYSPIDSIIQVDDAKQATQLISQVTLRNIVGSKTLNVLLTSRQQL 195
            .:|:|||...:.::||.||.:.:....:..:....:|.|.:.|.|::.::..::|..:|..|:.:
Mouse   179 HEVVTKDMFIMEIDAVCYYRMENASLLLSSLAHVSKAIQFLVQTTMKRLLAHRSLTEILLERKSI 243

  Fly   196 SREIQQAVAGITYRWGVRVERVDVMDITLPTSLERSLASEAEAVREARAKIILAEGELKASKALK 260
            :::::.|:..:|..||::|||.::.|:.||..|:.|||.||||.|:|:.::|.||||..||::|:
Mouse   244 AQDVKVALDAVTCIWGIKVERTEIKDVRLPAGLQHSLAVEAEAQRQAKVRVIAAEGEKAASESLR 308

  Fly   261 EASDVMSENKITLQLRHLQILSSIASERRVRIIYPIPLEIMEPFMSGKEGQKKDG 315
            .|::::|.....:|||:|..|.|:::|:...::.|:|.:::.  :....|.:..|
Mouse   309 MAAEILSGTPAAVQLRYLHTLQSLSTEKPATVVLPLPFDMLS--LLSSPGNRAQG 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14736	NP_731666.2	SPFH_like	100..305	CDD:473137	68/205 (33%)
Nphs2	NP_569723.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..64		5/13 (38%)
		SPFH_podocin	124..346	CDD:259809	78/221 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	357..385		1/5 (20%)