Protein Alignment CG14736 and Phb2

DIOPT Version :9

• Sequence 1: NP_001287293.1
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_001013053.1
• Gene: Phb2 / 114766
• RGDID: 620203
• Length: 299
• Species: Rattus norvegicus
• Alignment Length: 268
• Identity: 56/268 - (20%)
• Similarity: 106/268 - (39%)
• Gaps: 78/268 - (29%)

  Fly    95 GRLRKGLRGPG--LVFILPC-------------IDETHRVDMRTDVTNVRPQDVLTKDSVTITVN 144
            |||..|.||.|  |..:|..             ::..||......:..|: ||.:..:.:...:.
  Rat    10 GRLPSGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQ-QDTILAEGLHFRIP 73

  Fly   145 AVVYYCIY----------SPIDS-----------IIQVDDAKQATQLISQV-------------- 174
            ...|..||          ||..|           ::...:|::...:..::
  Rat    74 WFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVN 138

  Fly   175 -TLRNIVGSKTLNVLLTSRQQLSREIQQAVAGITYRWGVRVERVDVMDITLPTSLERSLASEAEA 238
             .|:::|.....:.|:|.|.|:|..|::.:......:.:.::.|.:.:::.  |.|.:.|.||:.
  Rat   139 EVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSF--SREYTAAVEAKQ 201

  Fly   239 V----------------REARAKIILAEGELKASKALKEASDVMSENKITLQLRHLQILSSIA-- 285
            |                :|.|.||:.||||.:|:|.|.||   :|:|...::||.::...:|:
  Rat   202 VAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEA---LSKNPGYIKLRKIRAAQNISKT 263

  Fly   286 ---SERRV 290
               |:.|:
  Rat   264 IATSQNRI 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14736	NP_001287293.1	PHB	78..225	CDD:214581	30/180 (17%)
		SPFH_like	100..305	CDD:302763	53/263 (20%)
Phb2	NP_001013053.1	Necessary for transcriptional repression. /evidence=ECO:0000250|UniProtKB:Q99623	19..49		4/29 (14%)
		PHB	39..201	CDD:214581	26/164 (16%)
		SPFH_prohibitin	40..235	CDD:259799	35/197 (18%)
		Necessary for transcriptional repression. /evidence=ECO:0000250|UniProtKB:Q99623	150..174		6/23 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900