Protein Alignment CG14736 and nphs2

DIOPT Version :10

• Sequence 1: NP_731666.2
• Gene: CG14736 / 41466
• FlyBaseID: FBgn0037986
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: XP_017949096.1
• Gene: nphs2 / 100498000
• XenbaseID: XB-GENE-485101
• Length: 376
• Species: Xenopus tropicalis
• Alignment Length: 313
• Identity: 100/313 - (31%)
• Similarity: 162/313 - (51%)
• Gaps: 29/313 - (9%)

  Fly     7 RKDAATNSEMSKHDQKIPP-----------------KEFKRPSADGGPRPPPSRYIQTSEDNKDS 54
            |..::.|.|.:|:|.|:..                 ...:....|.|.:|...|
 Frog    40 RSRSSQNRESAKNDTKVSAVVDVDDVVGSDAETEIMALLETSQKDDGVKPAGFR----------- 93

  Fly    55 TFEKVAIGICWFLVIITFPFSMCCCLTIVPEYSRMIILRLGRLRKG-LRGPGLVFILPCIDETHR 118
            .||.:.|..|..|||:|.|.|:..|:.:|.||.|.:|.||||:..| .|||||.|.|||:|:.|:
 Frog    94 VFEGLLIFCCLLLVILTLPLSIWFCVKVVREYERAVIFRLGRMLSGRARGPGLFFYLPCLDKCHK 158

  Fly   119 VDMRTDVTNVRPQDVLTKDSVTITVNAVVYYCIYSPIDSIIQVDDAKQATQLISQVTLRNIVGSK 183
            ||.|.....|....::|||.||:.::.:.||.:.:....:..|.....|.||:.|.|.:.::..:
 Frog   159 VDFRLKTFEVPFHQIVTKDLVTLEIDVICYYRLENACLFLTSVSSISSAFQLLVQTTTKRLLAHR 223

  Fly   184 TLNVLLTSRQQLSREIQQAVAGITYRWGVRVERVDVMDITLPTSLERSLASEAEAVREARAKIIL 248
            ....:|..|:.:..|::.|:...|..||::|||.::.|:.||..:::|:|.||||.|.|:.|:|.
 Frog   224 AFLDILLERKSIGEEVKVALDAATCHWGIKVERTEIKDVKLPEEVKQSMAVEAEAQRHAKVKVIA 288

  Fly   249 AEGELKASKALKEASDVMSENKITLQLRHLQILSSIASERRVRIIYPIPLEIM 301
            ||||...|:.:|.|::.:|.:...:|||:|..|..:.||:....:.|:|.::|
 Frog   289 AEGEKTVSEYIKLAAEKLSGSPTAIQLRYLHTLQCMTSEKPATFVLPLPFDLM 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14736	NP_731666.2	SPFH_like	100..305	CDD:473137	70/203 (34%)
nphs2	XP_017949096.1	SPFH_podocin	116..338	CDD:259809	78/221 (35%)