Protein Alignment CG31358 and STOML1

DIOPT Version :10

• Sequence 1: NP_650147.1
• Gene: CG31358 / 41462
• FlyBaseID: FBgn0051358
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_004800.2
• Gene: STOML1 / 9399
• HGNCID: 14560
• Length: 398
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 82/276 - (29%)
• Similarity: 137/276 - (49%)
• Gaps: 37/276 - (13%)

  Fly    34 FVSWILVLILLPFSLCCCLTIAYEFHRLVIFRLGRIRSCLGPGLVFLLPCIDSFNTVDIRTDVVN 98
            |:.::|:|:..|.|....|.|...:.|:::|||||||:..|||:|.|||.||||..||:||...|
Human    61 FLGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRTRAFN 125

  Fly    99 VDPQEMLTKDSVSITVNAVVFYCIYDPINSIIKVDDARDATERISQVTLRNIVGSKGLHELLASR 163
            |.|.::.:||...::|.|.|.:.|:||:.|::.|.|...||...:|..:...:..:.|.|:...:
Human   126 VPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKRPLREIQMEK 190

  Fly   164 QQLSLEIQQAVAKITERWGVRVERVDL-MEI------------SLPSSLER-----------SLA 204
            .::|.::...:..:|..||:.|:||:| :|.            :|.|:|::           |:|
Human   191 LKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPNLDSTLQQLALHFLGGSMNSMA 255

  Fly   205 SEAEATREARAKIILAEGEAKASK--ALKECSDVMSENQITLQLRHLQILCSMASERRV------ 261
            ..|.:...|....:::|.|..|.:  |.......::|..:|.    ||...|.|...:|
Human   256 GGAPSPGPADTVEMVSEVEPPAPQVGARSSPKQPLAEGLLTA----LQPFLSEALVSQVGACYQF 316

  Fly   262 NVLFPIPLEIMAPFMD 277
            ||:.|...: .|.|:|
Human   317 NVVLPSGTQ-SAYFLD 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31358	NP_650147.1	SPFH_like	74..276	CDD:473137	65/233 (28%)
STOML1	NP_004800.2	Tyrosine-type lysosomal sorting signal. /evidence=ECO:0000255, ECO:0000269|PubMed:19696025	6..10
		SPFH_SLP-1	94..224	CDD:259814	47/129 (36%)
		SCP2	311..395	CDD:460423	6/22 (27%)