DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spt3 and supt3h

DIOPT Version :9

Sequence 1:	NP_650146.1	Gene:	Spt3 / 41461	FlyBaseID:	FBgn0037981	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_021322818.1	Gene:	supt3h / 436898	ZFINID:	ZDB-GENE-040718-370	Length:	380	Species:	Danio rerio

Alignment Length:	408	Identity:	98/408 - (24%)
Similarity:	160/408 - (39%)	Gaps:	122/408 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 TNPSPQQINLAGHNVAGGASGSNVANVLIPDDAPVSLLTEIADIMRSFGDSDQPRTGSVKLVEQI 130
            |..|.:..|.|...:...:|.|.....       .|.:.|:..:|.:.|||.:|...:..|||.|
Zfish     4 TTMSAKMSNSAASPMTANSSSSRSGKA-------TSFIPELQSMMFALGDSRRPLHETAALVEDI 61

  Fly   131 LQQQLRGIFNEASLVAMRRKQNPCPSQADFEFLMRNHPVKIARMRKHLK----DMRILKRF---- 187
            :..||..:.::|:.||:.|..... |..:..||||....||.|:.|:::    ..::||..
Zfish    62 VHTQLINLLHQAAEVALLRGARVI-SPEEIIFLMRKDKKKIRRLFKYMQFRDYKSKVLKTIDDED 125

  Fly   188 -------------LSIRTGRPQDFMDDLEQQ------EEDEELAIDVYELHDEDRMRRLFRADRI 233
                         .:.|....|||:..::|.      .||:||        ||.:..||.|.:::
Zfish   126 LLDSDKYSSSSSNANKRQRLAQDFLSSIDQTGEYLTLMEDDEL--------DEVKQERLERIEKM 182

  Fly   234 SQILTGQQYLEFNEARKTSFYCRHGEKIKNKFRRFLDLPA-DLRIPTPTMNILAYLAHETIAAIV 297
            ::.:...||.||.|:|:.||     .|..:|||.:||..: |::....:|.||:|||:||:|.:|
Zfish   183 TRNMDSSQYSEFCESRQLSF-----SKKASKFREWLDCSSLDVKPNAMSMEILSYLAYETVAQVV 242

  Fly   298 DYSILTRLNSDNRATEPYSRVTSA--------------------------------GGSPAMMHV 330
            |.::|.:.:...:..:|:....||                                .|....||
Zfish   243 DLALLVKQDMTPKTGDPFQHAISATYIQYCSSSAEASSSKKDLDSPDNTPPSTPSGAGHQGKMH- 306

  Fly   331 CPEVTQGRG---------------------------MEVVKPISVPEIHEAMRRFRQMSSRKIGR 368
              .:.||.|                           ...::|   ..|.||:||:    |.:||.
Zfish   307 --SLAQGNGGPNQDASSKAKQRKRKKSAAACVSETQSSAIQP---AHIREAIRRY----SHRIGP 362

  Fly   369 YRNSCDIDFRR---SFLA 383
            ......: :||   :|||
Zfish   363 LSPFSSV-YRRNGMTFLA 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spt3	NP_650146.1	TAF13	99..190	CDD:173962	28/111 (25%)
supt3h	XP_021322818.1	TAF13	32..123	CDD:242920	28/91 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586706
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I5109
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1552679at2759
OrthoFinder	1	1.000	-	-		FOG0006269
OrthoInspector	1	1.000	-	-		oto39175
orthoMCL	1	0.900	-	-		OOG6_105306
Panther	1	1.100	-	-	LDO	PTHR11380
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.900