Protein Alignment DCAF12 and Dcaf12l1

DIOPT Version :10

• Sequence 1: NP_650145.1
• Gene: DCAF12 / 41460
• FlyBaseID: FBgn0037980
• Length: 459
• Species: Drosophila melanogaster
• Sequence 2: NP_001101411.1
• Gene: Dcaf12l1 / 313296
• RGDID: 1563873
• Length: 501
• Species: Rattus norvegicus
• Alignment Length: 425
• Identity: 167/425 - (39%)
• Similarity: 247/425 - (58%)
• Gaps: 53/425 - (12%)

  Fly    75 NLCDYLRSRESGL----------RDRRSVNVEYTSRYVLTHDMLRETQISLGYINKVFCSKWLSS 129
            ::.:||:.|..|.          .|.||..|      :...::|||.|::||.:||||.|:||::
  Rat    88 SMVNYLKGRALGADGHPGFAGFEGDLRSYGV------LRLPELLRERQLTLGPLNKVFASQWLNA 146

  Fly   130 RQVVFGTKCNKLLVYDVNMRRVDAIPTLSNSRANHPEVQG-----GLHAIELSPSRSFLATGARN 189
            ||||.|||||.|.|.||....:..||.:   |...|::..     |:||:||:||::.||||..|
  Rat   147 RQVVCGTKCNTLFVVDVKTDHIMRIPLM---RDRVPDLSRGPPSCGIHAVELNPSKTLLATGGEN 208

  Fly   190 SSDIAVYRLPTLDPVCVGE-GGHRDLIMGMCWLDDQFLVSGSKDSRMALWRINEDHME-----FP 248
            .:.:|||:||||||||:|: .||||.|..:.|:.|...||||:|..:|||:::.|...     ..
  Rat   209 PNSLAVYQLPTLDPVCLGDCQGHRDWIFAIAWMSDTVAVSGSRDGTVALWKVDPDMFNGSIAWHK 273

  Fly   249 DGGEEACPTFATIHPLSVKEVRTA------QRIRSLCFNKEFKEIAALSLNGYIHIFNA-ETFKQ 306
            |.|   .|.:|.|.|..::.:..|      :::|:|.|:.:.:|:.|:||:||.|::.| .:..:
  Rat   274 DAG---LPVYAHISPTDMEAIPKATTNPGNRKVRALAFSNKNQELGAVSLDGYFHLWKARSSLSR 335

  Fly   307 TLSRKLPNCQDNVSIAYHSD-GLYAVGCRSYTILLDART-LQTIKKITSRYSGCGIRATSFEGNL 369
            .||.:||.|::||.:.|..: .|||||.:|:...||.|. .|.|..:.||..|.|:|:.|...::
  Rat   336 LLSLRLPYCRENVCLTYCDEFSLYAVGSQSHVSFLDLRQGQQNIPPLCSREGGTGVRSLSVHQHI 400

  Fly   370 LTVGTGLGMLLFYDIRAGKYLE--SSVN-------ASRTVALKCSKGIVYPEDEMDGF-QQVKYV 424
            :|||||.|.||||||||.|:||  |:.|       :.|.:.|.|..|.:..:|.::.: ..|:..
  Rat   401 VTVGTGHGSLLFYDIRAQKFLEERSAANPDMFPVPSGRKLKLTCGSGWINQDDLLENYVAGVEDF 465

  Fly   425 P-AIYTHCYDSTRMRLFAAGGPLPATLVGNYAGVW 458
            | |:|||||:...|:||..||||.:.|.|||||:|
  Rat   466 PNALYTHCYNWPEMKLFVGGGPLASGLHGNYAGLW 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCAF12	NP_650145.1	WD40 repeat	121..163	CDD:293791	21/41 (51%)
		WD40	<168..458	CDD:441893	128/320 (40%)
		WD40 repeat	173..210	CDD:293791	22/37 (59%)
		WD40 repeat	216..263	CDD:293791	16/51 (31%)
		WD40 repeat	275..311	CDD:293791	13/36 (36%)
		WD40 repeat	319..353	CDD:293791	13/35 (37%)
Dcaf12l1	NP_001101411.1	WD40	133..>327	CDD:475233	82/199 (41%)
		WD40 repeat	138..180	CDD:293791	21/44 (48%)
		WD40 repeat	191..230	CDD:293791	23/38 (61%)
		WD40 repeat	235..266	CDD:293791	12/30 (40%)
		WD40 repeat	268..297	CDD:293791	7/31 (23%)
		WD40 repeat	303..340	CDD:293791	13/36 (36%)
		WD40 repeat	348..386	CDD:293791	14/37 (38%)