Protein Alignment GCC185 and ranbp2

DIOPT Version :10

• Sequence 1: NP_001097755.1
• Gene: GCC185 / 41459
• FlyBaseID: FBgn0037979
• Length: 1135
• Species: Drosophila melanogaster
• Sequence 2: XP_073768430.1
• Gene: ranbp2 / 100317326
• ZFINID: ZDB-GENE-081104-93
• Length: 2746
• Species: Danio rerio
• Alignment Length: 977
• Identity: 194/977 - (19%)
• Similarity: 339/977 - (34%)
• Gaps: 281/977 - (28%)

  Fly    30 GLLNIAKKAKQAKDELTEENHRLKDALKRAAE--KQSSLPAMQEMVQDFT-----DKNLILTEEV 87
            |:.....||...:.:.:..:    |.||..||  |:....|:|....|..     |.|.:::.:.
Zfish  1423 GITEPQTKASDTQPQTSSAS----DLLKNIAELHKEKEKEAIQSSSDDSADTSAHDDNPLISGKA 1483

  Fly    88 N-----NLKRKTKEDADRLTQFEIENESLK------RQLGRLSDENDALLANVDRMEKAMQQVNA 141
            :     :|.:.:||.    .||..::.|.:      :||..:..:.|......|.|.:
Zfish  1484 DTFSFADLAKSSKEG----FQFGQQDPSFRGFAGAGQQLFTVLPKPDTSADQEDEMYR------- 1537

  Fly   142 LGNEQRKNLELL-------EVDIAKIKEAEAENASLRQQVATMEEESSVLQQK-YQNIKELNSEQ 198
              .|:..:::..       :||:...:|.|....|.|.::...:.|:|..::: ..|:|.|.:.|
Zfish  1538 --TEENDDIQFEPVVQMPDKVDLVTGEEDEKILYSQRVKLFRFDPETSQWKERGVGNLKLLKNNQ 1600

  Fly   199 RKKFNSLKDRFIDVHRKLKNLKECKCVLLETQ---HEYAASVSKWQVEIIKAS------QLLCAK 254
            ..|...|.       |:.:.||.|....:.|.   ...|.|...|.......|      :.|.||
Zfish  1601 NGKLRVLM-------RREQVLKVCANHWITTTMNLKPLAGSDRAWMWLASDFSDGDARLEQLAAK 1658

  Fly   255 MASLQ-AENEKLKLNNGKS---DNNPQT----IDTGIDRKRLLQRVQEMDRLAKIVKQ----KQK 307
            ..:.: ||..|.:....:.   |...||    ::|| ....|:|:.:||....|.:|.    :.|
Zfish  1659 FKTPELAEEFKQRFEECQRLLLDIPLQTPHKLVNTG-RTAHLIQKAEEMKSGLKDLKSFLTPQSK 1722

  Fly   308 NQRSNLNVEYLLKKITALEELAVIIKQQHRIDKEQLISVTKEQEN-----------TKNHARNLN 361
            .:.|:         :||....:||:|    :|.| ..|...|.:|           ||..|.:.:
Zfish  1723 EEESS---------VTADSTSSVIVK----LDSE-TTSTALEWDNYDLREGALKSYTKPSASDAS 1773

  Fly   362 V-------SLFQ----------------------TKLDQMQNLVKVIAKERDNQQRKLQELE--- 394
            |       |||:                      .||:|.|..|..     |::|...||.|
Zfish  1774 VQPDTVAKSLFRFGESTTGFSFSFQPILSPSKSPCKLNQSQASVGT-----DDEQDTSQEEERDG 1833

  Fly   395 -----------AICIELRQHNEDLLTRYHLKEQEHGELLTEMRELNEALKGRGDAISRLQEQHEA 448
                       .:.:...:.:|.:|..:..|...:.:.|::.:|     :|.|| :..||.....
Zfish  1834 QYFEPVVPMPDLVEVSTGEEDEQVLFSHRAKLYRYDKTLSQWKE-----RGIGD-LKILQHYETK 1892

  Fly   449 EVK--RQRDLEAQL-SNSQQAAQEKLQKIK--------------QLQSRVEEL------------ 484
            .|:  .:||...:| :|....:..||:.:|              :.|.:||:|
Zfish  1893 RVRLVMRRDQVLKLCANHWIDSSMKLEPMKGAEKAWIWSAFDFAEGQGKVEQLAVRFKLQDTASI 1957

  Fly   485 -----EQANADAQSDVLSTSTISRAEELSRLRELDEGYEEKYHKLRAIAAKLKKKLQEQTQQLNE 544
                 |:|......|.|.....:|  |.|.::|...|.       .|:|.     |:|.|::.:.
Zfish  1958 FRDVFEEAKTALDRDTLLNPRSAR--EASFIQESICGQ-------AAVAV-----LEETTKEPSG 2008

  Fly   545 MEQSGALKEELEAIKLAQAQLQQDLNAARAENQKL----KSKEKV----KHSSVLNLEIEAAEKS 601
            :.:..:.|.|    :...|:....::.......|.    .|.:|:    |.:|.:: .:..|::.
Zfish  2009 LPEHSSPKPE----RTPPAEFSTPVSKTVVSPPKFVFGSDSVQKIFGSPKENSAVS-PVRTADED 2068

  Fly   602 LSEVSAKLTAKSSELEAVKESLASKENTIVQLRKEIAI-----LEEAK-NGEAAHSLELKEQIDR 660
            ..|...|.:|.:|.......||.:| :...:|.|:..:     ..:|: ..:|..||:
Zfish  2069 SGESRLKTSAVTSSQAGTPFSLPTK-SLDFRLFKDNPMAFWTCTSDAQFEAQACPSLK------- 2125

  Fly   661 MQVQVKDAVHSKQQALTQNKDLE------HGVEQAKLEAEQL--------------RLQLSESAQ 705
             |..|:|..:...    .:.|||      ...|||.|.|..|              ..:..|..:
Zfish  2126 -QKSVQDLYNDDD----DDDDLEVIFERQPTREQADLAASLLLPHTFFCYKNRPGYTSEEEEDDE 2185

  Fly   706 QYESKLNTATQQLLSQTQELEMHLAEQKRLETALRNAERALEDLRVEYTEYKLKAQSVLRKNQNK 770
            .:||.:.:...||.....|..  |..:||.........|.|                :|......
Zfish  2186 DFESAVRSLQGQLYEDDHECV--LVWEKRASADEEQRARRL----------------LLPPTFLC 2232

  Fly   771 GSNREQELEEELV----------ALRESERNLRASNDGRAARLAQLDSQIEELRQDNTDLQ-KRS 824
            |.:.:.:||.|..          .|.:::..|..|:|...|..:.::.|..: |....||. |||
Zfish  2233 GVSSDSDLEPERAEDSSTHTQADTLTQTQVRLDPSHDASVASSSTMELQKTD-RSSPIDLSTKRS 2296

  Fly   825 KE 826
            .|
Zfish  2297 SE 2298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCC185	NP_001097755.1	PRK03918	<33..559	CDD:235175	132/660 (20%)
		Smc	<357..>920	CDD:440809	114/592 (19%)
		Grip	1057..1103	CDD:197860
ranbp2	XP_073768430.1	None