| Sequence 1: | NP_001262494.1 | Gene: | KLHL18 / 41458 | FlyBaseID: | FBgn0037978 | Length: | 575 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036421.2 | Gene: | KEAP1 / 9817 | HGNCID: | 23177 | Length: | 624 | Species: | Homo sapiens |
| Alignment Length: | 568 | Identity: | 206/568 - (36%) |
|---|---|---|---|
| Similarity: | 313/568 - (55%) | Gaps: | 50/568 - (8%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 SQVEDQYFVYKHDKLFGESFPLFKEIRRMGKLCDVTLKVEDQ-----TFSAHRVVLAATIPYFYA 66
Fly 67 MFTNNMAESRIKEITMKESAIEPSALESLINYVYSGQVRIDNQNVQNLMVGASFLQLSNVRDACA 131
Fly 132 SFLISRFHPHNVLGIRTFADSMICRQLIDAADKYIDQNFAKVSQSEEFLALDCEQLLELMRRDEL 196
Fly 197 NVRTEEVIFEACMKWVKYAEDKRSELFPQVLAAVRLPLLSPQFLADRVAREELIRSSHQCRDLLD 261
Fly 262 EA-------KDFHLMPERR------------------GLLQSFRTRQ------------RSGE-- 287
Fly 288 -FFTGQIYAVGGLASTGE---SVSTVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFN 348
Fly 349 GTERLSTVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGYDGVTSLNTVEVYYPKSNTW 413
Fly 414 KTVAQMMKYRSAGGVTQLNGYVYALGGHDGLSIFDSVERYDQAEDVWVKMSPMLNRRCRLGVATL 478
Fly 479 NGKIYVCGGYCGNSFLRSVECYDPQTDTWKLVTPMNCKRSRVALAANM 526 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KLHL18 | NP_001262494.1 | BTB | 29..135 | CDD:279045 | 40/110 (36%) |
| PHA03098 | 36..510 | CDD:222983 | 191/521 (37%) | ||
| BACK | 143..245 | CDD:285009 | 41/101 (41%) | ||
| Kelch | 292..339 | CDD:128874 | 17/49 (35%) | ||
| KELCH repeat | 329..372 | CDD:276965 | 16/42 (38%) | ||
| Kelch | 340..386 | CDD:128874 | 18/45 (40%) | ||
| KELCH repeat | 376..417 | CDD:276965 | 19/40 (48%) | ||
| Kelch | 387..433 | CDD:128874 | 19/45 (42%) | ||
| KELCH repeat | 423..466 | CDD:276965 | 18/42 (43%) | ||
| Kelch | 435..480 | CDD:128874 | 19/44 (43%) | ||
| Kelch_1 | 469..514 | CDD:279660 | 27/44 (61%) | ||
| KELCH repeat | 470..514 | CDD:276965 | 26/43 (60%) | ||
| Kelch_1 | 517..560 | CDD:279660 | 5/10 (50%) | ||
| KELCH repeat | 517..560 | CDD:276965 | 5/10 (50%) | ||
| KEAP1 | NP_036421.2 | BTB_POZ_KLHL19_KEAP1 | 56..180 | CDD:349557 | 42/125 (34%) |
| PHA03098 | 95..596 | CDD:222983 | 183/502 (36%) | ||
| Kelch 1 | 327..372 | 4/44 (9%) | |||
| KELCH repeat | 362..409 | CDD:276965 | 14/46 (30%) | ||
| Kelch 2 | 373..423 | 17/49 (35%) | |||
| KELCH repeat | 413..456 | CDD:276965 | 16/42 (38%) | ||
| Kelch 3 | 424..470 | 18/45 (40%) | |||
| KELCH repeat | 460..503 | CDD:276965 | 19/42 (45%) | ||
| Kelch 4 | 471..517 | 19/45 (42%) | |||
| KELCH repeat | 507..551 | CDD:276965 | 19/43 (44%) | ||
| Kelch 5 | 518..564 | 19/45 (42%) | |||
| KELCH repeat | 554..597 | CDD:276965 | 26/42 (62%) | ||
| Kelch 6 | 565..611 | 28/46 (61%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4441 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D312716at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X9 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.820 | |||||