DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment KLHL18 and AT5G28160

DIOPT Version :9

Sequence 1:	NP_001262494.1	Gene:	KLHL18 / 41458	FlyBaseID:	FBgn0037978	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_198168.1	Gene:	AT5G28160 / 832891	AraportID:	AT5G28160	Length:	324	Species:	Arabidopsis thaliana

Alignment Length:	394	Identity:	76/394 - (19%)
Similarity:	127/394 - (32%)	Gaps:	162/394 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 SFLQL-SNVRDACASFLISRFHPHNVLGIRTFADSMICRQLIDAADKYIDQNFAKVSQSEEFLAL 182
            |||.| ..:..:|.:.:...::|...|..:||...:|..:||.|
plant     9 SFLSLPDEIILSCLARISRSYYPKLSLVCKTFRTLLISNELIVA--------------------- 52

  Fly   183 DCEQLLELMRRDELNVRTEEVIFEACMK------------WVKYAEDKRSELFPQVLAAVRLPLL 235
                        .|:::|.|.....|:|            |:|          |..:...:|
plant    53 ------------RLHLKTHETFCHVCLKFPDKPNPSMFTLWIK----------PGTILTNQL--- 92

  Fly   236 SPQFLADRVAREELIRSSHQCRDLLDEAKDFHLMPERRGLLQSFRTRQRSGEFFTGQIYAVGGLA 300
                       |:..||:...|.:...:..::.:|....::.|             ::|   ||:
plant    93 -----------EKNKRSTRDTRLVQIPSSYYYNVPFYLVMVGS-------------EVY---GLS 130

  Fly   301 STGESVSTVEIYDP----LTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFNGTERLSTVEVYDP 361
            ...:..|.:.:.:.    |.|    ...|::.|::....|.|||:|..||....|.::..||:|.
plant   131 QRNDPSSNMFVRNKGDIFLCK----APNMTVARAKASAVVFNGKIYVMGGCMADESVNWGEVFDI 191

  Fly   362 RKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGYDGVTSLNTVEVY----YPKSNTWKTVAQMMKY 422
            :...|.               ||.|    .|.....:|:..::|:    |.:||..|
plant   192 KTQTWE---------------ALPD----PGPEFRFSSIRKIDVFQEKLYVRSNEKK-------- 229

  Fly   423 RSAGGVTQLNGYVYALGGHDGLSIFDSVERYDQAEDVW--VKMSPMLNRRCRLGVATL-----NG 480
                                     |||  ||..|: |  ||...||||  .||..|:     .|
plant   230 -------------------------DSV--YDPKEE-WRVVKGLDMLNR--NLGCGTIEIVHYGG 264

  Fly   481 KIYV 484
            |:.:
plant   265 KLLI 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KLHL18	NP_001262494.1	BTB	29..135	CDD:279045	5/16 (31%)
		PHA03098	36..510	CDD:222983	76/394 (19%)
		BACK	143..245	CDD:285009	16/113 (14%)
		Kelch	292..339	CDD:128874	9/50 (18%)
		KELCH repeat	329..372	CDD:276965	13/42 (31%)
		Kelch	340..386	CDD:128874	11/45 (24%)
		KELCH repeat	376..417	CDD:276965	10/44 (23%)
		Kelch	387..433	CDD:128874	7/49 (14%)
		KELCH repeat	423..466	CDD:276965	9/44 (20%)
		Kelch	435..480	CDD:128874	16/51 (31%)
		Kelch_1	469..514	CDD:279660	6/21 (29%)
		KELCH repeat	470..514	CDD:276965	5/20 (25%)
		Kelch_1	517..560	CDD:279660
		KELCH repeat	517..560	CDD:276965
AT5G28160	NP_198168.1	F-box	8..55	CDD:279040	13/78 (17%)
		Kelch_1	158..203	CDD:279660	16/63 (25%)
		KELCH repeat	159..202	CDD:276965	16/61 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910