DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KLHL18 and AT3G27910

DIOPT Version :9

Sequence 1:	NP_001262494.1	Gene:	KLHL18 / 41458	FlyBaseID:	FBgn0037978	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_189429.1	Gene:	AT3G27910 / 822414	AraportID:	AT3G27910	Length:	294	Species:	Arabidopsis thaliana

Alignment Length:	288	Identity:	65/288 - (22%)
Similarity:	109/288 - (37%)	Gaps:	75/288 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   292 QIYAVGGLASTGESVSTVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFNGTERLST- 355
            :||..||..: |:..|.|.:.|.|...::....|.:.|......:::||:|..||:|..:.|..
plant    48 KIYVFGGCIN-GDMTSNVFVIDCLHGTFQFLPSMRVPRGCAAFGIVDGKIYVIGGYNKADSLDNW 111

  Fly   356 VEVYDPRKNKWSQGCAMLCKRSAVGV----AALDDCIYVCGGYDGVTSLNTVEVYYPKSNTWKTV 416
            |||:|..|..| :..:.||......:    ..::..||:....:|:       |:.||...|:..
plant   112 VEVFDLEKQTW-ESFSGLCNEELSKITLKSVVMNKKIYIMDRGNGI-------VFDPKKGVWERD 168

  Fly   417 AQMMKYRSAGGVTQLNGYVYALGGHDGLSIFDSVER------YDQAEDVW---------VKMSPM 466
            ..:.:....|... ::..:|..|       ||||:|      ||.:..||         .||...
plant   169 FLLDRDWVVGSCV-IDNMLYTFG-------FDSVKRIYRVRVYDPSVRVWSFVKGIEDIPKMDGT 225

  Fly   467 LNRRCRLGVATLNGKIYVC------GGYCGNSFLRSVECYDPQTDTWKLVTPMNCKRSRVALAAN 525
            |..|    :|...||:.:.      ||                |:.|       |.:..:.....
plant   226 LGSR----MANHGGKLVILLNLDKNGG----------------TELW-------CIKIALERRGQ 263

  Fly   526 MGKLWA-IGGYD----GESNLSTVEVYD 548
            .|::|. |..|:    .|::.:.||.:|
plant   264 QGEIWGKILWYNLVLTLENSSTIVECFD 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KLHL18	NP_001262494.1	BTB	29..135	CDD:279045
		PHA03098	36..510	CDD:222983	56/243 (23%)
		BACK	143..245	CDD:285009
		Kelch	292..339	CDD:128874	11/46 (24%)
		KELCH repeat	329..372	CDD:276965	14/43 (33%)
		Kelch	340..386	CDD:128874	14/50 (28%)
		KELCH repeat	376..417	CDD:276965	7/44 (16%)
		Kelch	387..433	CDD:128874	8/45 (18%)
		KELCH repeat	423..466	CDD:276965	14/57 (25%)
		Kelch	435..480	CDD:128874	16/59 (27%)
		Kelch_1	469..514	CDD:279660	8/50 (16%)
		KELCH repeat	470..514	CDD:276965	8/49 (16%)
		Kelch_1	517..560	CDD:279660	8/37 (22%)
		KELCH repeat	517..560	CDD:276965	8/37 (22%)
AT3G27910	NP_189429.1	Kelch	48..94	CDD:128874	11/46 (24%)
		Kelch_1	83..123	CDD:279660	14/40 (35%)
		KELCH repeat	84..130	CDD:276965	15/46 (33%)
		KELCH repeat	173..213	CDD:276965	12/47 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910