DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KLHL18 and AT3G24610

DIOPT Version :9

Sequence 1:	NP_001262494.1	Gene:	KLHL18 / 41458	FlyBaseID:	FBgn0037978	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_001319634.1	Gene:	AT3G24610 / 822057	AraportID:	AT3G24610	Length:	375	Species:	Arabidopsis thaliana

Alignment Length:	234	Identity:	51/234 - (21%)
Similarity:	86/234 - (36%)	Gaps:	51/234 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 PQVLAAVRLPLLSPQFLADRVAREELIRSSHQCRDLLDEAKDFHLMPERRGLLQSFRTRQRSGEF 288
            |:.:|.:.|..:|      |:....|...|..||.::       |.||      .::||...|
plant    32 PEAVAMICLARVS------RLDHAALSLVSKSCRSMV-------LSPE------LYQTRSLIG-- 75

  Fly   289 FTGQIYAVGGLASTGESVS-----------TVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLY 342
            :..:...|.....|.|::.           .|...|..:.||.....|.:.|....|:|::||:.
plant    76 YAEKFLYVCFCMPTDETLCCHEKINGNRSLNVLFLDCRSHKWHHVTSMRVARVSPEVSVVDGKIN 140

  Fly   343 AFGGFNGTERLSTVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGYDGVTSLNTVEVYY 407
            .:||..........||:||:...|:.        .::.....::.|||...:|       |..||
plant   141 VWGGCKYKHYYDWGEVFDPKTQTWAD--------MSIPKPVREEKIYVVDSWD-------VGSYY 190

  Fly   408 --PKSNTWKTVAQMMKYRSAGGVTQLNGYVYALGGHDGL 444
              |..:.|:...|..| ||..... ::..:|:.|...|:
plant   191 YLPSKSIWEKGNQDSK-RSKDWCL-IDKLIYSCGNDGGI 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KLHL18	NP_001262494.1	BTB	29..135	CDD:279045
		PHA03098	36..510	CDD:222983	51/234 (22%)
		BACK	143..245	CDD:285009	5/20 (25%)
		Kelch	292..339	CDD:128874	11/57 (19%)
		KELCH repeat	329..372	CDD:276965	12/42 (29%)
		Kelch	340..386	CDD:128874	8/45 (18%)
		KELCH repeat	376..417	CDD:276965	9/42 (21%)
		Kelch	387..433	CDD:128874	13/47 (28%)
		KELCH repeat	423..466	CDD:276965	5/22 (23%)
		Kelch	435..480	CDD:128874	3/10 (30%)
		Kelch_1	469..514	CDD:279660
		KELCH repeat	470..514	CDD:276965
		Kelch_1	517..560	CDD:279660
		KELCH repeat	517..560	CDD:276965
AT3G24610	NP_001319634.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910