Protein Alignment KLHL18 and NSP3

DIOPT Version :10

• Sequence 1: NP_650143.1
• Gene: KLHL18 / 41458
• FlyBaseID: FBgn0037978
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: NP_566545.1
• Gene: NSP3 / 820886
• AraportID: AT3G16390
• Length: 467
• Species: Arabidopsis thaliana
• Alignment Length: 497
• Identity: 97/497 - (19%)
• Similarity: 177/497 - (35%)
• Gaps: 128/497 - (25%)

  Fly    96 INYVYSGQ-------VRIDNQNVQNLMVGASFLQLSNVRDACASFLISRFHPHNVLGIRTFADSM 153
            :..||.||       |:.:..|...::||....:.:.                  ||:..|.
plant    24 VTKVYVGQGQYGIAFVKFEYANGSEVVVGDEHGEKTE------------------LGVEEFE--- 67

  Fly   154 ICRQLIDAAD--KYIDQNFAKVSQSEEFLALDCEQLLELMRRDELNVRTEEVIFEACMKWVKYA- 215
                 ||:.|  .|::....|||.      :..|.:..|..:......::.::.:..:|:|.:.
plant    68 -----IDSDDYIVYVEGYREKVSD------MTSEMITFLSFKTSKGKTSQPIVKKPGVKFVLHGG 121

  Fly   216 -----EDKRSELFPQVLAAVRLPLLSPQFLADRVAREEL-----IRSSHQCRDLLDEAKDFHLMP 270
                 ..:.:::...:.|.|.|| .:|:.|.:.:..|:.     :|.||
plant   122 KIVGFHGRSTDVLHSLGAYVSLP-STPKLLGNWIKVEQNGEGPGLRCSH---------------- 169

  Fly   271 ERRGLLQSFRTRQRSGEFFTGQIYAVGGLASTGESVST-VEIYDPLTKKWKM----GEQMSMMRS 330
               |:.|           ...:||:.||.....:.:.. :.::|..|:.|.:    |:...:...
plant   170 ---GIAQ-----------VGNKIYSFGGELIPNQPIDKHLYVFDLETRTWSIAPATGDVPHLSCL 220

  Fly   331 RVGVAVLNGKLYAFGGFNGTERLSTVEVYDPRKNKW------SQGCAMLCKRSAVGVAALDDCIY 389
            .|.:..:...||.|||.:.:.:.:....:|...|:|      .:|..   .||...:||.::.:|
plant   221 GVRMVSVGSTLYTFGGRDFSRQYNGFYSFDTTTNEWKLLTPVEEGPT---PRSFHSMAADEENVY 282

  Fly   390 VCGGYDGVTSLNTVEVYYPKSNTW---KTVAQMMKYRSAGGVTQLNGYVYALGGHDGLSIFDSVE 451
            |.||...:..:.|::.|.....||   .........|...|:..:.|.|:.:.|.:|..: |.|.
plant   283 VFGGVGAMDRIKTLDSYNIVDKTWFHCSNPGDSFSIRGGAGLEVVQGKVWIVYGFNGCEV-DDVH 346

  Fly   452 RYDQAEDVWVKMSPM---LNRRCRLGVATLNGKIYVCGG--------YCG-NSFLRSVECYDPQT 504
            .||.|||.|.::...   .|.|.....|.:...|.:.||        :.| ...:......|.:|
plant   347 FYDPAEDKWTQVETFGVKPNERSVFASAAIGKHIVIFGGEIAMDPRAHVGPGQLIDGTFALDTET 411

  Fly   505 DTWKLV-----TPMNCKRSRVALAANMGKLWAIGGYDGESNL 541
            ..|:.:     ||    .||...|:..|.:      ||:..|
plant   412 LQWERLDKFEGTP----SSRGWTASTTGTI------DGKKGL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLHL18	NP_650143.1	BTB_POZ_KLHL18	20..137	CDD:349556	8/47 (17%)
		PHA03098	36..510	CDD:222983	88/459 (19%)
		KELCH repeat	329..372	CDD:276965	10/48 (21%)
		KELCH repeat	376..417	CDD:276965	12/43 (28%)
		KELCH repeat	423..466	CDD:276965	14/42 (33%)
		KELCH repeat	470..514	CDD:276965	11/57 (19%)
		Kelch_1	517..560	CDD:396078	7/25 (28%)
		KELCH repeat	517..560	CDD:276965	7/25 (28%)
NSP3	NP_566545.1	PLN02193	1..467	CDD:177844	97/497 (20%)
		KELCH repeat	166..211	CDD:276965	12/74 (16%)
		KELCH repeat	215..266	CDD:276965	9/50 (18%)
		KELCH repeat	269..311	CDD:276965	12/41 (29%)
		KELCH repeat	319..365	CDD:276965	14/46 (30%)
		KELCH repeat	368..417	CDD:276965	9/48 (19%)