DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment KLHL18 and AT2G44700

DIOPT Version :9

Sequence 1:	NP_001262494.1	Gene:	KLHL18 / 41458	FlyBaseID:	FBgn0037978	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_181998.1	Gene:	AT2G44700 / 819078	AraportID:	AT2G44700	Length:	368	Species:	Arabidopsis thaliana

Alignment Length:	191	Identity:	44/191 - (23%)
Similarity:	76/191 - (39%)	Gaps:	39/191 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 STVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGY--DGVTS----LNTVEVYYPKSNT 412
            |.:.::|.|..:..||..:|.||....|..:...:||.|||  |.:.:    |||        .|
plant   144 SRLSIFDTRFGELRQGPCLLVKRGYNCVGLVGGKVYVIGGYQDDEIAAESFDLNT--------QT 200

  Fly   413 WKTVAQMMKYRSAGGVTQLN----GYVYALGGHDGLSIFD----SVERYDQAEDVWVKMSPMLNR 469
            |:......:..|...:.:.|    ..|.||...:|::.:|    |.:|.:...|.|
plant   201 WEAAPIPDEKESHRWICKANVSFDRKVCALRSREGMTCYDTRDGSCQRSEMPNDQW--------- 256

  Fly   470 RCRLGVATLNGKIYVCGGYCGNSFLRSVECYDPQTDTWKLVTPMNCKRSR-VALAANMGKL 529
             .|:|:..::..::|.....|      :..||.:...|::|...:...:| |.:....|||
plant   257 -SRVGLCVIDNVLFVYFSRFG------LMWYDSKLMLWRVVYGFDLDNARSVGIGEYYGKL 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
KLHL18	NP_001262494.1	BTB	29..135	CDD:279045
		PHA03098	36..510	CDD:222983	38/169 (22%)
		BACK	143..245	CDD:285009
		Kelch	292..339	CDD:128874
		KELCH repeat	329..372	CDD:276965	5/17 (29%)
		Kelch	340..386	CDD:128874	9/31 (29%)
		KELCH repeat	376..417	CDD:276965	13/46 (28%)
		Kelch	387..433	CDD:128874	13/55 (24%)
		KELCH repeat	423..466	CDD:276965	11/50 (22%)
		Kelch	435..480	CDD:128874	11/48 (23%)
		Kelch_1	469..514	CDD:279660	8/44 (18%)
		KELCH repeat	470..514	CDD:276965	8/43 (19%)
		Kelch_1	517..560	CDD:279660	5/14 (36%)
		KELCH repeat	517..560	CDD:276965	5/14 (36%)
AT2G44700	NP_181998.1	F-box	28..73	CDD:279040
		KELCH repeat	123..162	CDD:276965	5/17 (29%)
		KELCH repeat	166..207	CDD:276965	13/48 (27%)
		Kelch_1	166..205	CDD:279660	13/46 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910