DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment KLHL18 and bath-15

DIOPT Version :9

Sequence 1:NP_001262494.1 Gene:KLHL18 / 41458 FlyBaseID:FBgn0037978 Length:575 Species:Drosophila melanogaster
Sequence 2:NP_001348656.1 Gene:bath-15 / 182393 WormBaseID:WBGene00015590 Length:313 Species:Caenorhabditis elegans


Alignment Length:240 Identity:59/240 - (24%)
Similarity:98/240 - (40%) Gaps:58/240 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 LSDNSQVEDQYFVY----------KHDKLFGESFPLFKEIRRMGK-LCDVTLKVEDQTFSAHRVV 56
            :|.:|..||  |:|          |..|:.|.|..:.:......| ..||.|.|.|:.|...::.
 Worm   104 VSWDSLTED--FLYDNSFTIEACVKITKMTGFSKDVLRSFDESEKRFSDVILVVGDEKFYVLKLF 166

  Fly    57 LAATIPYFYAMFTNNMAESRIKEITMKESAIEPSALESLINYVYSGQVRIDNQNVQNLMVGASFL 121
            ||:...||.|:|.....|:...|:|::.  |:|:..:||:..:| |:..||:..:..:::.|..|
 Worm   167 LASHSSYFNALFLGKFKEADQSEVTLQN--IDPTDFQSLLEVLY-GEPAIDDGTIDGVLLLAHML 228

  Fly   122 QLSNVRDACASFLISRFHPHNVLGIRTFADSM-ICRQLIDAADKYIDQNFAKVSQSEEFLALDCE 185
            .::.....|..|||.:              || ..|:|:..|::|..:|...|..|         
 Worm   229 DVTLAIRKCEEFLIEK--------------SMKSMRELLKMANQYQLENLKTVCIS--------- 270

  Fly   186 QLLELMRRDELNVRTEEVIFEACMKWVKYAEDKRSELFPQVLAAV 230
                     ::|...|   .||.|.:      ...|:.|.|||.:
 Worm   271 ---------KINTIDE---IEAAMAY------NPEEMDPIVLATL 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KLHL18NP_001262494.1 BTB 29..135 CDD:279045 28/106 (26%)
PHA03098 36..510 CDD:222983 49/197 (25%)
BACK 143..245 CDD:285009 19/89 (21%)
Kelch 292..339 CDD:128874
KELCH repeat 329..372 CDD:276965
Kelch 340..386 CDD:128874
KELCH repeat 376..417 CDD:276965
Kelch 387..433 CDD:128874
KELCH repeat 423..466 CDD:276965
Kelch 435..480 CDD:128874
Kelch_1 469..514 CDD:279660
KELCH repeat 470..514 CDD:276965
Kelch_1 517..560 CDD:279660
KELCH repeat 517..560 CDD:276965
bath-15NP_001348656.1 MATH 14..127 CDD:279285 6/24 (25%)
BTB 141..245 CDD:306997 30/120 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.