DRSC/TRiP Functional Genomics Resources

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Protein Alignment KLHL18 and hpo-9

DIOPT Version :9

Sequence 1:NP_001262494.1 Gene:KLHL18 / 41458 FlyBaseID:FBgn0037978 Length:575 Species:Drosophila melanogaster
Sequence 2:NP_504839.1 Gene:hpo-9 / 179117 WormBaseID:WBGene00015463 Length:581 Species:Caenorhabditis elegans


Alignment Length:255 Identity:69/255 - (27%)
Similarity:111/255 - (43%) Gaps:22/255 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 FKEIRRMGKLCDVTLKVEDQT-FSAHRVVLAATIPYFYAMFTNNMAESRIKEITMKESAIEPSAL 92
            |.||.......||||.::|.| |:|||::||....:|.||......||..:.:|::|:  ...|.
 Worm    54 FDEIFTSTDHSDVTLVLDDGTEFAAHRLILAVRSSFFRAMLYTGFQESHQQLVTLQET--NSVAF 116

  Fly    93 ESLINYVYSGQVRIDNQNVQNLMVGASFLQLSNVRD------ACASFLISRFHPHNVLGIRTFAD 151
            .:::.|:|:.  :||...|: |.:...:|.|::..|      |.:.:........|:..|...|.
 Worm   117 RAVLRYMYTS--KIDFAGVE-LDILLEYLSLAHRYDLIQLMTAISEYFKEILKNENLCSIFNAAY 178

  Fly   152 SMICRQLIDAADKYIDQNFAKVSQSEEFLALDCEQLLELMRRDELNVRTEEVIFEACMKWVKYAE 216
            ......|||...:|.|::..::.:...|..|..:.|.||:.||.. ...|..||.|...| ....
 Worm   179 FFQFTDLIDYCMQYSDKHADQLLEDPSFNRLSGDSLKELLARDSF-FALELKIFNAVRSW-HQNN 241

  Fly   217 DKRSELFPQVLAAVRLPLLSPQFLADRVAREELIRSSHQCRDLLD----EAKDFHLMPER 272
            ....|....:|..|||||::...|.:.|....|:.:.    .|||    :.:..|.:|.|
 Worm   242 PTMKEASKVLLELVRLPLITQTELLNCVRPTGLVSAD----TLLDAIEVQTQRPHEIPFR 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KLHL18NP_001262494.1 BTB 29..135 CDD:279045 33/112 (29%)
PHA03098 36..510 CDD:222983 66/248 (27%)
BACK 143..245 CDD:285009 27/101 (27%)
Kelch 292..339 CDD:128874
KELCH repeat 329..372 CDD:276965
Kelch 340..386 CDD:128874
KELCH repeat 376..417 CDD:276965
Kelch 387..433 CDD:128874
KELCH repeat 423..466 CDD:276965
Kelch 435..480 CDD:128874
Kelch_1 469..514 CDD:279660
KELCH repeat 470..514 CDD:276965
Kelch_1 517..560 CDD:279660
KELCH repeat 517..560 CDD:276965
hpo-9NP_504839.1 BTB_POZ_BTBD9 42..161 CDD:349596 33/111 (30%)
BACK_BTBD9 165..265 CDD:350518 27/101 (27%)
F5_F8_type_C 461..557 CDD:366285
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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