Protein Alignment KLHL18 and klhl28

DIOPT Version :9

• Sequence 1: NP_001262494.1
• Gene: KLHL18 / 41458
• FlyBaseID: FBgn0037978
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_017207216.1
• Gene: klhl28 / 100333404
• -ID: -
• Length: 571
• Species: Danio rerio
• Alignment Length: 532
• Identity: 209/532 - (39%)
• Similarity: 294/532 - (55%)
• Gaps: 15/532 - (2%)

  Fly    32 IRRMGKLCDVTLKVEDQTFSAHRVVLAATIPYFYAMFTNNMAESRIKEITMKESAIEPSALESLI 96
            :|:..:|||:.|:|.|....||:||||:..|||.||||.|::|....|:..:  .|:.:||::::
Zfish    28 LRQDHELCDIVLRVGDAKIHAHKVVLASISPYFKAMFTGNLSEKETSEVEFQ--CIDEAALKAIV 90

  Fly    97 NYVYSGQVRIDNQNVQNLMVGASFLQLSNVRDACASFLISRFHPHNVLGIRTFADSMICRQLIDA 161
            .|.|:|.|.|..:.|::|:..|:.||:..|...|.|||.|:....|.:||..||::..|..|..|
Zfish    91 EYAYTGTVFISQETVESLLPAANLLQVKLVLKECCSFLESQLDAGNCIGISRFAETYGCHDLCLA 155

  Fly   162 ADKYIDQNFAKVSQSEEFLALDCEQLLELMRRDELNVRTEEVIFEACMKWVKYAEDKRSELFPQV 226
            |.|:|.|:|.:|.|:|||..|...:|.:::..|.|||.|||.:|.|...|:||...:|.:...|:
Zfish   156 ASKFICQHFEEVCQTEEFFELTRAELDDIVSNDCLNVLTEESVFYALESWIKYDVSERQQHLAQL 220

  Fly   227 LAAVRLPLLSPQFLADRVAREELIRSSHQCRDLLDEAKDFHLMPERRGLLQS-FRTRQRSGEFFT 290
            |..|||||||.:||........|||..|.|:.||:||..:|.|||.|...|: ..||.|..   .
Zfish   221 LHCVRLPLLSVKFLTRLYEANHLIRDDHACKHLLNEALKYHFMPEHRLSYQTVLSTRPRCA---P 282

  Fly   291 GQIYAVGGLASTGESVSTVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFNGTERL-- 353
            ..:.||||.|....::.::|:|.|.|..|.....:.:.|...|||||..::|..||.....|.
Zfish   283 KVLLAVGGKAGLFATLESMEMYFPQTDSWLGLAPLPVPRYEFGVAVLEQQVYVLGGIATHMRQGI 347

  Fly   354 ------STVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGYDGVTSLNTVEVYYPKSNT 412
                  |:||.:.|..|.||....|...||.:||..|...:|..|||||...|.:||.|.||...
Zfish   348 SYRRHESSVERWHPDTNTWSSERRMAESRSTLGVVVLAGELYALGGYDGQYYLQSVEKYLPKLKE 412

  Fly   413 WKTVAQMMKYRSAGGVTQLNGYVYALGGHDGLSIFDSVERYDQAEDVWVKMSPMLNRRCRLGVAT 477
            |:.||.|.|.||......|:|.:||:||: |.:..:||||||.::|.|..::||.::|...||..
Zfish   413 WQPVAPMTKSRSCFATAVLDGMIYAIGGY-GPAHMNSVERYDPSKDSWDMVAPMADKRINFGVGV 476

  Fly   478 LNGKIYVCGGYCGNSFLRSVECYDPQTDTWKLVTPMNCKRSRVALAANMGKLWAIGGYDGESNLS 542
            :.|.|:|.||:.|.|.|.|:|.|||..:.|....|||..|:.|..|.....|:.:||:.|.|.|:
Zfish   477 MLGFIFVVGGHNGVSHLSSIERYDPYQNQWTACRPMNEPRTGVGSAVVDNLLYVVGGHSGSSYLN 541

  Fly   543 TVEVYDPETDKW 554
            .|:.|||.||.|
Zfish   542 AVQRYDPLTDGW 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLHL18	NP_001262494.1	BTB	29..135	CDD:279045	40/102 (39%)
		PHA03098	36..510	CDD:222983	189/482 (39%)
		BACK	143..245	CDD:285009	43/101 (43%)
		Kelch	292..339	CDD:128874	16/46 (35%)
		KELCH repeat	329..372	CDD:276965	17/50 (34%)
		Kelch	340..386	CDD:128874	17/53 (32%)
		KELCH repeat	376..417	CDD:276965	18/40 (45%)
		Kelch	387..433	CDD:128874	20/45 (44%)
		KELCH repeat	423..466	CDD:276965	17/42 (40%)
		Kelch	435..480	CDD:128874	18/44 (41%)
		Kelch_1	469..514	CDD:279660	18/44 (41%)
		KELCH repeat	470..514	CDD:276965	18/43 (42%)
		Kelch_1	517..560	CDD:279660	16/38 (42%)
		KELCH repeat	517..560	CDD:276965	16/38 (42%)
klhl28	XP_017207216.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59391
OrthoDB	1	1.010	-	-		D312716at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.930