Protein Alignment Ect3 and GLB1L2

DIOPT Version :9

• Sequence 1: NP_650142.1
• Gene: Ect3 / 41457
• FlyBaseID: FBgn0260746
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_001357389.1
• Gene: GLB1L2 / 89944
• HGNCID: 25129
• Length: 690
• Species: Homo sapiens
• Alignment Length: 672
• Identity: 231/672 - (34%)
• Similarity: 329/672 - (48%)
• Gaps: 114/672 - (16%)

  Fly    33 FLKDGEPFRFIAGSFHYFRAHPATWQRHLRTMRAAGLNAVTTYVEWSLHNPRDGVYVWSGIADLE 97
            |:.:...|....||.||||.....|:..|..|:|.|||.:||||.|:||.|..|.:.:||..|||
Human    54 FMLEDSTFWIFGGSIHYFRVPREYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDLE 118

  Fly    98 HFIRLAVGEDLLVILRPGPYICAERDMGGFPYWLLNKYPGIQLRTADVNYLSEIRIWYTQLFAKM 162
            .|:.:|....|.||||||||||:|.|:||.|.|||.. ||::|||....:...:.:::..|.:::
Human   119 AFVLMAAEIGLWVILRPGPYICSEMDLGGLPSWLLQD-PGMRLRTTYKGFTEAVDLYFDHLMSRV 182

  Fly   163 NKYLYGNGGPIIMVQVENEYGSFYACDLNYRNWLRDETESHVKG-QAVLFTNDGPSVLRCGKIQG 226
            ....|..|||||.||||||||| |..|..|..:::...|.  :| ..:|.|:|....|..|.:||
Human   183 VPLQYKRGGPIIAVQVENEYGS-YNKDPAYMPYVKKALED--RGIVELLLTSDNKDGLSKGIVQG 244

  Fly   227 ------------------------------------------------------VLATMDFGATN 237
                                                                  ||||::..:|:
Human   245 DPQPGGLCSSSRELHGCSPKLARLSVAPHLKLNFFLRGAHSILLPAFFSPSHLPVLATINLQSTH 309

  Fly   238 DLKPIWAKFRRYQPKGPLVNAEYYPGWLTHWTEPMANVSTQSITSTFINMLDHGASVNFYMFYGG 302
            :|:.:.......|...|.:..||:.||...|..|...:.:..:..|...::|.|:|:|.|||:||
Human   310 ELQLLTTFLFNVQGTQPKMVMEYWTGWFDSWGGPHNILDSSEVLKTVSAIVDAGSSINLYMFHGG 374

  Fly   303 TNFGFTAGANDIGPGNYMADITSYDYDAPMTEAGDPTPKYQALRRIIGRYLPLPNQPVPGPVPKR 367
            |||||..||...  .:|.:|:|||||||.:|||||.|.||..||...|....:|..|.|..:||.
Human   375 TNFGFMNGAMHF--HDYKSDVTSYDYDAVLTEAGDYTAKYMKLRDFFGSISGIPLPPPPDLLPKM 437

  Fly   368 SYGTVRLTTCCSLLSSEARSRLSTGFVQSAKPKSFEAL------GQYSGLVLYETWLPSFQRDPS 426
            .|..  ||....|...:|...|... ::|.||.:.|.|      ||..|.:||||.:.|    ..
Human   438 PYEP--LTPVLYLSLWDALKYLGEP-IKSEKPINMENLPVNGGNGQSFGYILYETSITS----SG 495

  Fly   427 ILSVPGLADRGYVYVDGEFVGILARETPVFELPLSASAGRRFQIIVENQGRINYGRQLND-FKGI 490
            ||| ..:.|||.|:|:...:|.|..:|....:|| .......:|:|||:||:|||..::| .||:
Human   496 ILS-GHVHDRGQVFVNTVSIGFLDYKTTKIAVPL-IQGYTVLRILVENRGRVNYGENIDDQRKGL 558

  Fly   491 LRDVRLDKQVLSNWNM----------TQFPLESYDNLEQLITQSDEAVRQGFQELKKLRTMLRTG 545
            :.::.|:...|.|:.:          .:|.|:.:.:|.:..|.
Human   559 IGNLYLNDSPLKNFRIYSLDMKKSFFQRFGLDKWSSLPETPTL---------------------- 601

  Fly   546 PAIYHGQLDIQKESDLADTYLDMSGWGKGIVFVNGENLGRYWPLVGPQVTLYVPAAVLKAGSNRL 610
            ||.:.|.|.|  .|...||:|.:.||.||:||:||:||||||. :|||.|||:|...|.:|.|::
Human   602 PAFFLGSLSI--SSTPCDTFLKLEGWEKGVVFINGQNLGRYWN-IGPQKTLYLPGPWLSSGINQV 663

  Fly   611 VVVEYQQTPASQELHFRDTPIL 632
            :|  :::|.|...|.|.:||.|
Human   664 IV--FEETMAGPALQFTETPHL 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ect3	NP_650142.1	Glyco_hydro_35	32..350	CDD:279624	133/371 (36%)
		BetaGal_dom4_5	<576..616	CDD:290101	21/39 (54%)
GLB1L2	NP_001357389.1	Glyco_hydro_35	53..417	CDD:307464	132/368 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153131
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52178
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100579
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.660