DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ect3 and BGAL5

DIOPT Version :9

Sequence 1:	NP_650142.1	Gene:	Ect3 / 41457	FlyBaseID:	FBgn0260746	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_175127.1	Gene:	BGAL5 / 841080	AraportID:	AT1G45130	Length:	732	Species:	Arabidopsis thaliana

Alignment Length:	774	Identity:	183/774 - (23%)
Similarity:	287/774 - (37%)	Gaps:	219/774 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFSVVVLVALLP------LLGAVSANRTFVVDYEKDQFLKDGEPFRFIAGSFHYFRAHPATWQR 59
            |..:::||..:|.      |:|: |..:...|.|:|...:.:|.....::||.||.|:.|..|:.
plant     1 MGTTILVLSKILTFLLTTMLIGS-SVIQCSSVTYDKKAIVINGHRRILLSGSIHYPRSTPEMWED 64

  Fly    60 HLRTMRAAGLNAVTTYVEWSLHNPRDGVYVWSGIADLEHFIRLAVGEDLLVILRPGPYICAERDM 124
            .::..:..||:.:.|||.|:.|.|..|.|.:.|..||..||:......|.|.||.|||:|||.:.
plant    65 LIKKAKDGGLDVIDTYVFWNGHEPSPGTYNFEGRYDLVRFIKTIQEVGLYVHLRIGPYVCAEWNF 129

  Fly   125 GGFPYWLLNKY-PGIQLRTADVNYLSEIRIWYTQLFAKM---NKYLYGNGGPIIMVQVENEYGSF 185
            ||||.||  || .||..||.:..:.|.:: .:|:...:|   :::....|||||:.|:|||:..
plant   130 GGFPVWL--KYVDGISFRTDNGPFKSAMQ-GFTEKIVQMMKEHRFFASQGGPIILSQIENEFEP- 190

  Fly   186 YACDL--------NYRNWLRDETESHVKGQAVLFTNDGPSVLRCGKIQG---VLATMDFGATNDL 239
               ||        :|.||         ..:..:..|.|...:.|.:...   ::.|.: |...|.
plant   191 ---DLKGLGPAGHSYVNW---------AAKMAVGLNTGVPWVMCKEDDAPDPIINTCN-GFYCDY 242

  Fly   240 KPIWAKFRRYQPKGPLVNAEYYPGWLTHWTEPMANVSTQSITSTFINMLDHGAS-VNFYMFYGGT 303
                  |...:|..|.:..|.:.||.|.:...:.....:.:.......:..|.| :|:||::|||
plant   243 ------FTPNKPYKPTMWTEAWSGWFTEFGGTVPKRPVEDLAFGVARFIQKGGSYINYYMYHGGT 301

  Fly   304 NFGFTAGANDIGPGNYMADITSYDYDAPMTEAG-DPTPKYQALRRI------------------- 348
            |||.|||      |.::.  ||||||||:.|.| ...|||..|:::
plant   302 NFGRTAG------GPFIT--TSYDYDAPIDEYGLVQEPKYSHLKQLHQAIKQCEAALVSSDPHVT 358

  Fly   349 -IGRYLP--------------LPNQPVPGPVP----KRSY-----GTVRLTTCCSLLSSEARSRL 389
             :|.|..              |.|..:..|..    .|.|     ....|..|.:::.:.|....
plant   359 KLGNYEEAHVFTAGKGSCVAFLTNYHMNAPAKVVFNNRHYTLPAWSISILPDCRNVVFNTATVAA 423

  Fly   390 STGFVQSAKPKSFEALGQYSGLVLYET-----------------------------------WL- 418
            .|..||...          ||.:||..                                   |.
plant   424 KTSHVQMVP----------SGSILYSVARYDEDIATYGNRGTITARGLLEQVNVTRDTTDYLWYT 478

  Fly   419 --------PSFQRD---PSILSVPGLADRGYVYVDGEFVGIL--ARETPVFELPLSAS---AGRR 467
                    .||.|.   |: |:|.......:|:|:|.|.|..  .||...|......:   ...:
plant   479 TSVDIKASESFLRGGKWPT-LTVDSAGHAVHVFVNGHFYGSAFGTRENRKFSFSSQVNLRGGANK 542

  Fly   468 FQIIVENQGRINYGRQLNDF-KGILRDVRL------DKQVLSNWNMTQFPLESYDNLEQLITQSD 525
            ..::....|..|.|.....: .||:..|.|      :|.:  :|....:..........|::.::
plant   543 IALLSVAVGLPNVGPHFETWATGIVGSVVLHGLDEGNKDL--SWQKWTYQAGLRGESMNLVSPTE 605

  Fly   526 EA---------VRQGFQELKKLRTMLRTGPAIYHGQLDIQKESD-LADTYLDMSGWGKGIVFVNG 580
            ::         .:|..|.|           ..|....|..:.:: ||   ||:...|||..::||
plant   606 DSSVDWIKGSLAKQNKQPL-----------TWYKAYFDAPRGNEPLA---LDLKSMGKGQAWING 656

  Fly   581 ENLGRYWPLVG-------------------------PQVTLYVPAAVLKAGSNRLVVVE 614
            :::||||....                         .|...:||.:.||...|.||:.|
plant   657 QSIGRYWMAFAKGDCGSCNYAGTYRQNKCQSGCGEPTQRWYHVPRSWLKPKGNLLVLFE 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ect3	NP_650142.1	Glyco_hydro_35	32..350	CDD:279624	104/354 (29%)
Ect3	NP_650142.1	BetaGal_dom4_5	<576..616	CDD:290101	15/64 (23%)
BGAL5	NP_175127.1	Glyco_hydro_35	37..340	CDD:279624	104/333 (31%)
BGAL5	NP_175127.1	BetaGal_dom4_5	<472..552	CDD:290101	15/80 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820