DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ect3 and BGAL4

DIOPT Version :9

Sequence 1:	NP_650142.1	Gene:	Ect3 / 41457	FlyBaseID:	FBgn0260746	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_200498.1	Gene:	BGAL4 / 835789	AraportID:	AT5G56870	Length:	724	Species:	Arabidopsis thaliana

Alignment Length:	756	Identity:	197/756 - (26%)
Similarity:	291/756 - (38%)	Gaps:	206/756 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VVLVALLPLLGAVSANRTFVVDYEKDQFLKDGEPFRFIAGSFHYFRAHPATWQRHLRTMRAAGLN 70
            :.::..|.|...|.|:    |.|::...:.:|:....::||.||.|:.|..|...::..:..||:
plant    13 LAILCCLSLSCIVKAS----VSYDRKAVIINGQRRILLSGSIHYPRSTPEMWPGLIQKAKEGGLD 73

  Fly    71 AVTTYVEWSLHNPRDGVYVWSGIADLEHFIRLAVGEDLLVILRPGPYICAERDMGGFPYWLLNKY 135
            .:.|||.|:.|.|..|.|.:....||..||:|.....|.|.||.|||:|||.:.||||.||  |:
plant    74 VIETYVFWNGHEPSPGQYYFGDRYDLVKFIKLVHQAGLYVNLRIGPYVCAEWNFGGFPVWL--KF 136

  Fly   136 -PGIQLRT------ADVNYLSEIRIWYTQLFAKMNKYLYGNGGPIIMVQVENEYG----SFYACD 189
             ||:..||      |.:...:|..:|    ..|..|.....|||||:.|:|||||    ...|..
plant   137 VPGMAFRTDNEPFKAAMKKFTEKIVW----MMKAEKLFQTQGGPIILAQIENEYGPVEWEIGAPG 197

  Fly   190 LNYRNWLRDETESHVKGQAVLFTNDGPSVLRCGKIQG---VLATMDFGATNDLKP-------IWA 244
            ..|..|:         .|..|..:.|...:.|.:...   ::.|.:.....|.||       :|
plant   198 KAYTKWV---------AQMALGLSTGVPWIMCKQEDAPGPIIDTCNGYYCEDFKPNSINKPKMW- 252

  Fly   245 KFRRYQPKGPLVNAEYYPGWLTHWTEPMANVSTQSITSTFINMLDHGAS-VNFYMFYGGTNFGFT 308
                         .|.:.||.|.:...:.....:.|..:....:..|.| ||:||::|||||..|
plant   253 -------------TENWTGWYTDFGGAVPYRPVEDIAYSVARFIQKGGSLVNYYMYHGGTNFDRT 304

  Fly   309 AGANDIGPGNYMADITSYDYDAPMTEAGDP-TPKY---QALRRIIGRYLPL---PNQPVPGPVPK 366
            |       |.:||  :|||||||:.|.|.| .|||   :||.:.|....|.   .:..|.....|
plant   305 A-------GEFMA--SSYDYDAPLDEYGLPREPKYSHLKALHKAIKLSEPALLSADATVTSLGAK 360

  Fly   367 R-SYGTVRLTTCCSLLS-----SEAR--------------------------------------- 386
            : :|.....::|.:.||     |.||
plant   361 QEAYVFWSKSSCAAFLSNKDENSAARVLFRGFPYDLPPWSVSILPDCKTEVYNTAKVNAPSVHRN 425

  Fly   387 -----SRLSTGFVQSAKPKSFEALGQY--SGLV--LYETWLPS----------------FQR--D 424
                 ::.|.|....|.|.:.|| |.:  :|||  :..||..|                |.:  |
plant   426 MVPTGTKFSWGSFNEATPTANEA-GTFARNGLVEQISMTWDKSDYFWYITDITIGSGETFLKTGD 489

  Fly   425 PSILSVPGLADRGYVYVDGEFVGI----LARETPVFELPLSASAG-RRFQIIVENQGRINYGRQL 484
            ..:|:|.......:|:|:|:..|.    |......|...:...|| .:..::....|..|.|...
plant   490 SPLLTVMSAGHALHVFVNGQLSGTAYGGLDHPKLTFSQKIKLHAGVNKIALLSVAVGLPNVGTHF 554

  Fly   485 NDF-KGILRDVRLDKQVLSNWNMTQF-----------PLESYDNLEQLITQSDEAVR--QG-FQE 534
            ..: ||:|..|.|.......|:|:::           .|..:.|.|      ...||  || |..
plant   555 EQWNKGVLGPVTLKGVNSGTWDMSKWKWSYKIGVKGEALSLHTNTE------SSGVRWTQGSFVA 613

  Fly   535 LKKLRTMLRTGPAIYHGQLDIQKESDLADTYLDMSGWGKGIVFVNGENLGRYWPLVGPQVT---- 595
            .|:..|..::..|...|      ...||   |||:..|||.|::||.|:||:||....|.:
plant   614 KKQPLTWYKSTFATPAG------NEPLA---LDMNTMGKGQVWINGRNIGRHWPAYKAQGSCGRC 669

  Fly   596 ----------------------LYVPAAVLKAGSNRLVVVE 614
                                  .:||.:.||: .|.:||.|
plant   670 NYAGTFDAKKCLSNCGEASQRWYHVPRSWLKS-QNLIVVFE 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ect3	NP_650142.1	Glyco_hydro_35	32..350	CDD:279624	108/343 (31%)
Ect3	NP_650142.1	BetaGal_dom4_5	<576..616	CDD:290101	17/65 (26%)
BGAL4	NP_200498.1	PLN03059	5..724	CDD:166698	197/756 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820