DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ect3 and BGAL14

DIOPT Version :9

Sequence 1:	NP_650142.1	Gene:	Ect3 / 41457	FlyBaseID:	FBgn0260746	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_001154292.1	Gene:	BGAL14 / 830016	AraportID:	AT4G38590	Length:	1052	Species:	Arabidopsis thaliana

Alignment Length:	797	Identity:	187/797 - (23%)
Similarity:	289/797 - (36%)	Gaps:	247/797 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKFSVVVLVALLPLLGAVSANRTFVVDYEKDQFLKDGEPFRFI------AGSFHYFRAHPA---- 55
            ||.....|:|:|.::...|...:...:.:|.....||....||      ..||.:|.:.|:
plant     1 MKSRTRYLIAILLVISLCSKASSHDDEKKKKGVTYDGSERNFIDHKWKKRASFLWFCSLPSKHTS 65

  Fly    56 ---TWQRHLRTMRAAGLNAVTTYVEWSLHNPRDGVYVWSGIADLEHFIRLAVGEDLLVILRPGPY 117
               .|...:...|..|||.:.|||.|::|.|..|.|.:.|..||..||:|...:.|.|.||.||:
plant    66 RKHMWPSIIDKARIGGLNTIQTYVFWNVHEPEQGKYDFKGRFDLVKFIKLIHEKGLYVTLRLGPF 130

  Fly   118 ICAERDMGGFPYWLLNKYPGIQLRTADVNYLSEIRIWYTQLFAKM--NKYLYGNGGPIIMVQVEN 180
            |.||.:.||.||| |.:.|.:..||.:..:......:..::...|  .|.....|||||:.|:||
plant   131 IQAEWNHGGLPYW-LREVPDVYFRTNNEPFKEHTERYVRKILGMMKEEKLFASQGGPIILGQIEN 194

  Fly   181 EYGSFYACDLNYRNWLRDETESHVKGQAVLFTNDGPSVLRCGKIQGVLATMDFGATNDLKPIWAK 245
            ||.   |..|.|    ::..|.::|..|                 .::.:|:.|..      |..
plant   195 EYN---AVQLAY----KENGEKYIKWAA-----------------NLVESMNLGIP------WVM 229

  Fly   246 FRRYQPKGPLVNA-------EYYPG---------WLTHWT-------EPMANVSTQSITSTFINM 287
            .::....|.|:||       :.:||         |..:||       :|....:.:.|..:....
plant   230 CKQNDAPGNLINACNGRHCGDTFPGPNRHDKPSLWTENWTTQFRVFGDPPTQRTVEDIAFSVARY 294

  Fly   288 LD-HGASVNFYMFYGGTNFGFTAGANDIGPGNYMADITSYDYDAPMTEAG-DPTPKYQALRRI-- 348
            .. :|:.||:||::||||||.|:       .:::.  |.|..|||:.|.| :..|||..|:.:
plant   295 FSKNGSHVNYYMYHGGTNFGRTS-------AHFVT--TRYYDDAPLDEFGLEKAPKYGHLKHVHR 350

  Fly   349 ------------------IG-----RYLPLPNQPVPGP---------------------VPKRSY 369
                              :|     ||...|...|...                     :|.||.
plant   351 ALRLCKKALFWGQLRAQTLGPDTEVRYYEQPGTKVCAAFLSNNNTRDTNTIKFKGQDYVLPSRSI 415

  Fly   370 GTVRLTTCCSLLSSEAR---SRLSTGFVQSAKPK---SFEALGQ--------------------- 407
            ..  |..|.:::.:.|:   ......||:|.|..   .||...:
plant   416 SI--LPDCKTVVYNTAQIVAQHSWRDFVKSEKTSKGLKFEMFSENIPSLLDGDSLIPGELYYLTK 478

  Fly   408 ----YSGLVLYETWLPSFQRDPSILSVPGLADRGYVYVDGEFVGIL--ARETPVFEL--PLSASA 464
                |:.:.:.|...|..:...:||.|..|.....|||:||:.|..  ..|...||.  |::...
plant   479 DKTDYACVKIDEDDFPDQKGLKTILRVASLGHALIVYVNGEYAGKAHGRHEMKSFEFAKPVNFKT 543

  Fly   465 G-RRFQIIVENQGRINYGRQLN------------DFKGILRDVRLDKQVLSNWNMTQFPLESYDN 516
            | .|..|:....|..:.|..:.            ..|...||
plant   544 GDNRISILGVLTGLPDSGSYMEHRFAGPRAISIIGLKSGTRD----------------------- 585

  Fly   517 LEQLITQSDE----AVRQGFQELKKLRTMLRTGPAIYHGQLDIQKESD-------LADTYLD--- 567
                :|:::|    |..:|  |.|::.|        ..|...::.|.|       ...||.:
plant   586 ----LTENNEWGHLAGLEG--EKKEVYT--------EEGSKKVKWEKDGKRKPLTWYKTYFETPE 636

  Fly   568 --------MSGWGKGIVFVNGENLGRYW-----PLVGPQVTLY-VPAAVLKA--GSNRLVVVEYQ 616
                    |...|||:::|||..:||||     ||..|..|.| :|.:.:|.  ..|.||::|.:
plant   637 GVNAVAIRMKAMGKGLIWVNGIGVGRYWMSFLSPLGEPTQTEYHIPRSFMKGEKKKNMLVILEEE 701

  Fly   617 QTPASQELHF----RDT 629
            .....:.:.|    |||
plant   702 PGVKLESIDFVLVNRDT 718

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ect3	NP_650142.1	Glyco_hydro_35	32..350	CDD:279624	100/377 (27%)
Ect3	NP_650142.1	BetaGal_dom4_5	<576..616	CDD:290101	18/47 (38%)
BGAL14	NP_001154292.1	PLN03059	65..831	CDD:166698	172/733 (23%)
		Glyco_hydro_35	67..350	CDD:279624	92/322 (29%)
		Gal_Lectin	754..831	CDD:280328
		PRP1_N	921..1050	CDD:283962
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820