DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ect3 and BGAL1

DIOPT Version :9

Sequence 1:	NP_650142.1	Gene:	Ect3 / 41457	FlyBaseID:	FBgn0260746	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_187988.1	Gene:	BGAL1 / 820584	AraportID:	AT3G13750	Length:	847	Species:	Arabidopsis thaliana

Alignment Length:	794	Identity:	202/794 - (25%)
Similarity:	309/794 - (38%)	Gaps:	221/794 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SVVVLVAL--LPLLGAVSANRTFVVDYEKDQFLKDGEPFRFIAGSFHYFRAHPATWQRHLRTMRA 66
            :||.:.|:  |.|||.:..:.:..|.|:......:|:....|:||.||.|:.|..|...:|..:.
plant    10 NVVAMAAVSALFLLGFLVCSVSGSVSYDSRAITINGKRRILISGSIHYPRSTPEMWPDLIRKAKE 74

  Fly    67 AGLNAVTTYVEWSLHNPRDGVYVWSGIADLEHFIRLAVGEDLLVILRPGPYICAERDMGGFPYWL 131
            .||:.:.|||.|:.|.|..|.|.:.|..||..|::|.....|.:.||.|||:|||.:.||||.||
plant    75 GGLDVIQTYVFWNGHEPSPGKYYFEGNYDLVKFVKLVQQSGLYLHLRIGPYVCAEWNFGGFPVWL 139

  Fly   132 LNKY-PGIQLRTADVNYLSEIRIWYTQL--FAKMNKYLYGNGGPIIMVQVENEYG----SFYACD 189
              || |||..||.:..:.::::.:.|::  ..|..:.....|||||:.|:|||||    ...|..
plant   140 --KYIPGISFRTDNGPFKAQMQRFTTKIVNMMKAERLFESQGGPIILSQIENEYGPMEYELGAPG 202

  Fly   190 LNYRNWLRDETESHVKGQA-VLFTND---GPSVLRCGKIQGVLATMDFGATNDLKPIWAKFRRYQ 250
            .:|.||..........|.. |:...|   .|.:..|....     .|:.:.|         :.|:
plant   203 RSYTNWAAKMAVGLGTGVPWVMCKQDDAPDPIINACNGFY-----CDYFSPN---------KAYK 253

  Fly   251 PKGPLVNAEYYPGWLTHWTEPMANVSTQSITSTFINMLDHGAS-VNFYMFYGGTNFGFTAGANDI 314
            ||   :..|.:.||.|.:..|:.....:.:..:....:..|.| :|:||::||||||.|||
plant   254 PK---MWTEAWTGWFTKFGGPVPYRPAEDMAFSVARFIQKGGSFINYYMYHGGTNFGRTAG---- 311

  Fly   315 GPGNYMADITSYDYDAPMTEAG-DPTPKY---QALRRIIGRYLPLPNQPVPGPVPKRSYGTVRLT 375
              |.::|  ||||||||:.|.| :..||:   :.|.|.|....|......|..:|..:|....:
plant   312 --GPFIA--TSYDYDAPLDEYGLERQPKWGHLKDLHRAIKLCEPALVSGEPTRMPLGNYQEAHV- 371

  Fly   376 TCCSLLSSEARSRLSTGFVQSAKPKSFEALGQYSGLVLYETWLPSFQRD---------------- 424
                   .:::|...:.|:.:..|||:..:...:.......|..|...|
plant   372 -------YKSKSGACSAFLANYNPKSYAKVSFGNNHYNLPPWSISILPDCKNTVYNTARVGAQTS 429

  Fly   425 -PSILSVP---GLADRGY-----VYVDGEF--VGIL-----ARETPVF----------------- 456
             ..::.||   ||:.:.|     .|:|..|  ||::     .|:|..:
plant   430 RMKMVRVPVHGGLSWQAYNEDPSTYIDESFTMVGLVEQINTTRDTSDYLWYMTDVKVDANEGFLR 494

  Fly   457 --ELPLSA--SAGRRFQIIVENQ------------------------------------GRINYG 481
              :||...  |||....:.:..|                                    |..|.|
plant   495 NGDLPTLTVLSAGHAMHVFINGQLSGSAYGSLDSPKLTFRKGVNLRAGFNKIAILSIAVGLPNVG 559

  Fly   482 RQLNDFK-GILRDVRLD-----KQVLSNWNMTQFPL----ESYDNLEQLITQSDEAVRQG-FQEL 535
            .....:. |:|..|.|:     ::.|| |....:.:    ||. :|..|...|.....:| |...
plant   560 PHFETWNAGVLGPVSLNGLNGGRRDLS-WQKWTYKVGLKGESL-SLHSLSGSSSVEWAEGAFVAQ 622

  Fly   536 KKLRTMLRT---GPAIYHGQLDIQKESDLADTYLDMSGWGKGIVFVNGENLGRYWP---LVG--- 591
            |:..|..:|   .||         .:|.||   :||...|||.:::||::|||:||   .||
plant   623 KQPLTWYKTTFSAPA---------GDSPLA---VDMGSMGKGQIWINGQSLGRHWPAYKAVGSCS 675

  Fly   592 --------------------PQVTLYVPAAVLKAGSNRLVV------------------------ 612
                                .|...:||.:.||...|.|||
plant   676 ECSYTGTFREDKCLRNCGEASQRWYHVPRSWLKPSGNLLVVFEEWGGDPNGITLVRREVDSVCAD 740

  Fly   613 -VEYQQTPASQELH 625
             .|:|.|..:.:||
plant   741 IYEWQSTLVNYQLH 754

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ect3	NP_650142.1	Glyco_hydro_35	32..350	CDD:279624	109/333 (33%)
Ect3	NP_650142.1	BetaGal_dom4_5	<576..616	CDD:290101	19/90 (21%)
BGAL1	NP_187988.1	PLN03059	10..847	CDD:166698	202/794 (25%)
		Glyco_hydro_35	40..344	CDD:279624	108/330 (33%)
		Gal_Lectin	769..846	CDD:280328
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820