DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ect3 and BGAL8

DIOPT Version :9

Sequence 1:	NP_650142.1	Gene:	Ect3 / 41457	FlyBaseID:	FBgn0260746	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_001324192.1	Gene:	BGAL8 / 817395	AraportID:	AT2G28470	Length:	852	Species:	Arabidopsis thaliana

Alignment Length:	787	Identity:	186/787 - (23%)
Similarity:	290/787 - (36%)	Gaps:	251/787 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KFSVVVLVALLPLLGAVSANRTFVVDYEKDQFLKDGEPFRFIAGSFHYFRAHPATWQRHLRTMRA 66
            |..:::|:.|:.::.|.:||    |.|:....:.||:....|:||.||.|:.|..|...::..:.
plant    12 KMEMILLLILVIVVAATAAN----VTYDHRALVIDGKRKVLISGSIHYPRSTPEMWPELIQKSKD 72

  Fly    67 AGLNAVTTYVEWSLHNPRDGVYVWSGIADLEHFIRLAVGEDLLVILRPGPYICAERDMGGFPYWL 131
            .||:.:.|||.||.|.|....|.:.|..||..|::||....|.|.||.|||:|||.:.||||.|
plant    73 GGLDVIETYVFWSGHEPEKNKYNFEGRYDLVKFVKLAAKAGLYVHLRIGPYVCAEWNYGGFPVW- 136

  Fly   132 LNKYPGIQLRTADVNYLSEIRIWYTQL--FAKMNKYLYGNGGPIIMVQVENEYGSFYACDLNYRN 194
            |:..|||:.||.:..:..|::.:.|::  ..|..|.....|||||:.|:|||||:.   |..|
plant   137 LHFVPGIKFRTDNEPFKEEMQRFTTKIVDLMKQEKLYASQGGPIILSQIENEYGNI---DSAY-- 196

  Fly   195 WLRDETESHVKGQAVLFTNDGPSVLRCGKIQGVLATMDFGATNDLKPIWAKFRRYQPKGPLVN-- 257
              ....:|::|..|                 .:..::|.|..      |...::.....|::|
plant   197 --GAAAKSYIKWSA-----------------SMALSLDTGVP------WNMCQQTDAPDPMINTC 236

  Fly   258 -------------------AEYYPGWLTHWTEPMANVSTQSITSTFINMLDHGASV-NFYMFYGG 302
                               .|.:.||...:.:|......:.:..........|.:. |:||::||
plant   237 NGFYCDQFTPNSNNKPKMWTENWSGWFLGFGDPSPYRPVEDLAFAVARFYQRGGTFQNYYMYHGG 301

  Fly   303 TNFGFTAGANDIGPGNYMADITSYDYDAPMTEAG---------------------------DPT- 339
            |||..|:|...|.        ||||||||:.|.|                           |||
plant   302 TNFDRTSGGPLIS--------TSYDYDAPIDEYGLLRQPKWGHLRDLHKAIKLCEDALIATDPTI 358

  Fly   340 ---------------------------PKYQALRRIIGRYLPLPNQPVPGPVPKRSYGTVRLTTC 377
                                       .|..|.....|:...||           ::....|..|
plant   359 TSLGSNLEAAVYKTESGSCAAFLANVDTKSDATVTFNGKSYNLP-----------AWSVSILPDC 412

  Fly   378 CSLLSSEAR---SRLSTGFV-QSAKP---KSFEALGQYS-----------------GLV------ 412
            .::..:.|:   :..||.|. ||.||   .|.|...|:|                 ||:
plant   413 KNVAFNTAKINSATESTAFARQSLKPDGGSSAELGSQWSYIKEPIGISKADAFLKPGLLEQINTT 477

  Fly   413 ------LY----------ETWLPSFQRDPSILSVPGLADRGYVYVDGEFVGI-LARETPVFELPL 460
                  |:          ||:|.  :...::|.:..|....|.:::|:..|. ..::....::|:
plant   478 ADKSDYLWYSLRTDIKGDETFLD--EGSKAVLHIESLGQVVYAFINGKLAGSGHGKQKISLDIPI 540

  Fly   461 SASAG-RRFQIIVENQGRINYGR-------------QLNDFKGILRDVRLDKQVLSNWNMTQFPL 511
            :...| ....::....|..|||.             .|...|| ...:.|..|   .|.. |..|
plant   541 NLVTGTNTIDLLSVTVGLANYGAFFDLVGAGITGPVTLKSAKG-GSSIDLASQ---QWTY-QVGL 600

  Fly   512 ESYD------NLEQLITQSDEAVRQGFQELKKLRTMLRTGPAIYHGQLDIQKESDLADTYLDMSG 570
            :..|      :..:.:::|....:|               |.|:: :......|......:|.:|
plant   601 KGEDTGLATVDSSEWVSKSPLPTKQ---------------PLIWY-KTTFDAPSGSEPVAIDFTG 649

  Fly   571 WGKGIVFVNGENLGRYWP--LVG-------------------------PQVTLY-VPAAVLKAGS 607
            .||||.:|||:::|||||  :.|                         |..||| ||.:.||...
plant   650 TGKGIAWVNGQSIGRYWPTSIAGNGGCTESCDYRGSYRANKCLKNCGKPSQTLYHVPRSWLKPSG 714

  Fly   608 NRLVVVE 614
            |.||:.|
plant   715 NILVLFE 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ect3	NP_650142.1	Glyco_hydro_35	32..350	CDD:279624	103/396 (26%)
Ect3	NP_650142.1	BetaGal_dom4_5	<576..616	CDD:290101	21/67 (31%)
BGAL8	NP_001324192.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820