Protein Alignment Ect3 and Glb1l

DIOPT Version :10

• Sequence 1: NP_650142.1
• Gene: Ect3 / 41457
• FlyBaseID: FBgn0260746
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_083286.1
• Gene: Glb1l / 74577
• MGIID: 1921827
• Length: 646
• Species: Mus musculus
• Alignment Length: 636
• Identity: 271/636 - (42%)
• Similarity: 382/636 - (60%)
• Gaps: 26/636 - (4%)

  Fly     4 SVVVLVALLPLLGAVSANRTFVVDYEKDQFLKDGEPFRFIAGSFHYFRAHPATWQRHLRTMRAAG 68
            |:::.:.:|.||....| |:||||.|.|:||.||.|||:::||.||||..|..|...|..|:.:|
Mouse     7 SLLLRLVVLLLLSQAEA-RSFVVDREHDRFLLDGVPFRYVSGSLHYFRVPPVLWADRLLKMQLSG 70

  Fly    69 LNAVTTYVEWSLHNPRDGVYVWSGIADLEHFIRLAVGEDLLVILRPGPYICAERDMGGFPYWLLN 133
            ||||..||.|:.|.|..|:|.::|..||..|:..|...:||||||||||||||.:|||.|.|||
Mouse    71 LNAVQFYVPWNYHEPEPGIYNFNGSRDLIAFLNEAAKVNLLVILRPGPYICAEWEMGGLPSWLL- 134

  Fly   134 KYPGIQLRTADVNYLSEIRIWYTQLFAKMNKYLYGNGGPIIMVQVENEYGSFYACDLNYRNWLRD 198
            :.|.|.|||:|..:|..:..|:..|..|:..:||.|||.||.:||||||||:.|||..|...|..
Mouse   135 RNPNIHLRTSDPAFLEAVDSWFKVLLPKIYPFLYHNGGNIISIQVENEYGSYKACDFKYMRHLAG 199

  Fly   199 ETESHVKGQAVLFTNDGPSVLRCGKIQGVLATMDFGATNDLKPIWAKFRRYQPKGPLVNAEYYPG 263
            ...:.:..:.:|||.|||..||||.:||:..|:|||..:::..|::..|.|:|.|||||:|||.|
Mouse   200 LFRALLGDKILLFTTDGPHGLRCGSLQGLYTTIDFGPADNVTRIFSLLREYEPHGPLVNSEYYTG 264

  Fly   264 WLTHWTEPMANVSTQSITSTFINMLDHGASVNFYMFYGGTNFGFTAGANDIGPGNYMADITSYDY 328
            ||.:|.:..:..|:.::......||..|||||.|||:||||||:..||::  .|.::...|||||
Mouse   265 WLDYWGQNHSTRSSPAVAQGLEKMLKLGASVNMYMFHGGTNFGYWNGADE--KGRFLPITTSYDY 327

  Fly   329 DAPMTEAGDPTPKYQALRRIIGRYLPLPNQPVPGPVPKRSYGTVRLTTCCSLLSSEARSRLSTGF 393
            |||::||||||||..|:|.:|.::..:|..|:|.|.||..:|.:.::...:|||. .......|.
Mouse   328 DAPISEAGDPTPKLFAIRNVISKFQEIPLGPLPPPSPKMKFGPLTMSLDGNLLSF-LDFLCPQGP 391

  Fly   394 VQSAKPKSFEALGQYSGLVLYETWLPSFQRDPSILSVP--GLADRGYVYVDGEFVGILARETPVF 456
            :.|..|.:|||:....|.:||.|:|.|...:|:...||  |:.||.||.|||...|:|.|....
Mouse   392 IHSVLPLTFEAVKLDHGFMLYRTYLTSPVLEPTPFWVPNNGIHDRAYVMVDGVLKGVLERSLKQ- 455

  Fly   457 ELPLSASAGRRFQIIVENQGRINYGRQLNDFKGILRDVRLDKQVLSNWNMTQFPLESYDNLEQLI 521
            ||.|:.:.|.|..|::||.||:::|...:||||:|....|.:.:|:.|.|  |||
Mouse   456 ELYLTGTVGTRLDILLENMGRLSFGSNHSDFKGLLEAPLLGQTILTEWMM--FPL---------- 508

  Fly   522 TQSDEAVRQGF--QELKKLRTMLRTGPAIYHGQLDIQKESDLADTYLDMSGWGKGIVFVNGENLG 584
             :.|:.|:..|  |.:|:......:.||.|..:..:  ...|.||:|.:.||.||.|::||.|||
Mouse   509 -KVDKLVKWWFPLQLMKRALPQASSVPAFYSAKFPV--FGLLGDTFLYLPGWTKGQVWINGFNLG 570

  Fly   585 RYWPLVGPQVTLYVPAAVLKAGS-NRLVVVEYQQTPASQELHFRDTPILNA 634
            |||.:.|||.|||||..:|...| |::.::|.:..|.:.::.|.|.||||:
Mouse   571 RYWTMRGPQQTLYVPRLLLFGRSINKITLLELENVPHNPQVQFLDKPILNS 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ect3	NP_650142.1	Glyco_hydro_35	32..350	CDD:396048	155/317 (49%)
		BetaGal_dom4_5	<576..616	CDD:463857	21/40 (53%)
Glb1l	NP_083286.1	Glyco_hydro_35	34..349	CDD:396048	155/317 (49%)