Protein Alignment Ect3 and Glb1

DIOPT Version :9

• Sequence 1: NP_650142.1
• Gene: Ect3 / 41457
• FlyBaseID: FBgn0260746
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_033882.1
• Gene: Glb1 / 12091
• MGIID: 88151
• Length: 647
• Species: Mus musculus
• Alignment Length: 653
• Identity: 293/653 - (44%)
• Similarity: 388/653 - (59%)
• Gaps: 44/653 - (6%)

  Fly     8 LVALLPLLGAVS-----ANRTFVVDYEKDQFLKDGEPFRFIAGSFHYFRAHPATWQRHLRTMRAA 67
            |:|||.||||..     ..|||.:||.:|:|||||:|||:|:||.||||.....|:..|..|:.|
Mouse    12 LLALLQLLGAAHGIYNVTQRTFKLDYSRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMA 76

  Fly    68 GLNAVTTYVEWSLHNPRDGVYVWSGIADLEHFIRLAVGEDLLVILRPGPYICAERDMGGFPYWLL 132
            ||||:..||.|:.|.|:.|.|.:||..|:||||:||....||||||||||||||.||||.|.|||
Mouse    77 GLNAIQMYVPWNFHEPQPGQYEFSGDRDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLL 141

  Fly   133 NKYPGIQLRTADVNYLSEIRIWYTQLFAKMNKYLYGNGGPIIMVQVENEYGSFYACDLNYRNWLR 197
            .| ..|.||::|.:||..:..|...|..||...||.||||||.|||||||||::|||.:|..:|.
Mouse   142 EK-QSIVLRSSDPDYLVAVDKWLAVLLPKMKPLLYQNGGPIITVQVENEYGSYFACDYDYLRFLV 205

  Fly   198 DETESHVKGQAVLFTNDGPS--VLRCGKIQGVLATMDFGATNDLKPIWAKFRRYQPKGPLVNAEY 260
            .....|:....:|||.||.|  :|:||.:|.:.||:|||..|::...:...|:::|||||:|:|:
Mouse   206 HRFRYHLGNDVILFTTDGASEKMLKCGTLQDLYATVDFGTGNNITQAFLVQRKFEPKGPLINSEF 270

  Fly   261 YPGWLTHWTEPMANVSTQSITSTFINMLDHGASVNFYMFYGGTNFGFTAGANDIGPGNYMADITS 325
            |.|||.||.:|.:.|.|:::.::..|:|..||:||.|||.|||||.:..|||.    .|....||
Mouse   271 YTGWLDHWGKPHSTVKTKTLATSLYNLLARGANVNLYMFIGGTNFAYWNGANT----PYEPQPTS 331

  Fly   326 YDYDAPMTEAGDPTPKYQALRRIIGRYLPLPNQPVPGPVPKRSYGTVRLTTCCSLLSSEARSRL- 389
            ||||||::||||.|.||.|||.:|..:..:|..|:|...||.:||.|.|....::  :||...|
Mouse   332 YDYDAPLSEAGDLTKKYFALREVIQMFKEVPEGPIPPSTPKFAYGKVALRKFKTV--AEALGILC 394

  Fly   390 STGFVQSAKPKSFEALGQYSGLVLYETWLPSFQRDPS-ILSVP--GLADRGYVYVDGEFVGILAR 451
            ..|.|:|..|.:|..:.||.|.|||.|.||....:|. |.|.|  |:.||.||.|||...|||.|
Mouse   395 PNGPVKSLYPLTFTQVKQYFGYVLYRTTLPQDCSNPKPIFSSPFNGVRDRAYVSVDGVPQGILDR 459

  Fly   452 ETPVFELPLSASAGRRFQIIVENQGRINYGRQLNDFKGILRDVRLDKQVLSNWNMTQFPLESYDN 516
            .. :..|.:...||....|:|||.||:||||.:|||||::.::.::..||:||  |.|||    |
Mouse   460 NL-MTALNIRGKAGATLDILVENMGRVNYGRFINDFKGLISNMTINSTVLTNW--TVFPL----N 517

  Fly   517 LEQLITQ-------SDEAVRQGFQELKKLRTMLRTGPAIYHGQLDIQKE-SDL-ADTYLDMSGWG 572
            .|.::..       |||....|.........:|   |..|.|...|... .|| .||::...||.
Mouse   518 TEAMVRNHLWGREASDEGHLDGRSTSNSSDLIL---PTFYVGNFSIPSGIPDLPQDTFIQFPGWS 579

  Fly   573 KGIVFVNGENLGRYWPLVGPQVTLYVPAAVLKAGS-NRLVVVEYQQTPASQ------ELHFRDTP 630
            ||.|::||.|||||||.:|||.||:||..:|...: |.:.|:|.:..|.|:      .:.|.|||
Mouse   580 KGQVWINGFNLGRYWPTMGPQKTLFVPRNILTTSAPNNITVLELEFAPCSEGTPELCTVEFVDTP 644

  Fly   631 ILN 633
            :::
Mouse   645 VIS 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ect3	NP_650142.1	Glyco_hydro_35	32..350	CDD:279624	164/319 (51%)
		BetaGal_dom4_5	<576..616	CDD:290101	21/40 (53%)
Glb1	NP_033882.1	Glyco_hydro_35	41..355	CDD:279624	164/318 (52%)
		BetaGal_dom4_5	<553..621	CDD:290101	30/67 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843245
Domainoid	1	1.000	334	1.000	Domainoid score	I1130
eggNOG	1	0.900	-	-		E1_COG1874
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	508	1.000	Inparanoid score	I1318
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52178
OrthoDB	1	1.010	-	-		D179316at2759
OrthoFinder	1	1.000	-	-		FOG0002046
OrthoInspector	1	1.000	-	-		mtm8768
orthoMCL	1	0.900	-	-		OOG6_100579
Panther	1	1.100	-	-	O	PTHR23421
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5429
SonicParanoid	1	1.000	-	-		X1174
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800