Protein Alignment mfas and YLR001C

DIOPT Version :9

• Sequence 1: NP_788655.1
• Gene: mfas / 41455
• FlyBaseID: FBgn0260745
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_013101.1
• Gene: YLR001C / 850687
• SGDID: S000003991
• Length: 862
• Species: Saccharomyces cerevisiae
• Alignment Length: 578
• Identity: 116/578 - (20%)
• Similarity: 204/578 - (35%)
• Gaps: 207/578 - (35%)

  Fly   334 SGKKVTLFVPNDAAFMEYRGHHQQENNVEDAKAEASKPSIYKLHAVLGEVQLE-DVPNEKLLQ-- 395
            :|:|:|:||| .|:|.|.||:              :|||:. .|.|.|::.|| |..:.:.:|
Yeast   352 NGRKITIFVP-QASFNEDRGY--------------TKPSLL-YHFVEGKIDLEQDFSSLRPIQYA 400

  Fly   396 -TELPD--------------QKIRI----NSYQLPA---ALGLEPYRFAANCVPIEKHDKLSEQA 438
             |::.|              ||.:|    ..|.:..   .|..:||...              ..
Yeast   401 PTQIYDSAFCSSAKRLGGHCQKFKITRSNKGYYINGRFKILNTKPYEIG--------------NT 451

  Fly   439 LVHTLGGVLKPLTKNLMDIIRERADMSIMRTVLEKTNLSAMLEDDKPVTIFVPTDAAFDKLE--- 500
            .::::...|: |..:|:..:......||...:|::.||..:..:.|..||.:|...::|..:
Yeast   452 SIYSIDDDLQ-LPGDLVLSLAPENHCSISLMLLKELNLLDLPSNHKGYTILLPCMNSWDNNDLTI 515

  Fly   501 PHLRRALKEGRGCASNILKNHLL--DLTFCSLATVPGAKTTAYNLLGEPLLLNRTHRAANQTGPT 563
            .:||     ....|.|:|..:|:  ||.:.:..::   .||..||.|..:.:. ..:.......|
Yeast   516 DYLR-----SNKTALNLLMRNLIFEDLIYSNNYSI---STTVKNLYGNSVSIG-VQKIVGSQNLT 571

  Fly   564 PIYINNLAKII----DADIMGTNGVLHVID----------------------------------- 589
            .|.::.:.:.|    .:||....||:|.||
Yeast   572 KISVSTIKESIIIEESSDIFFNQGVIHPIDQLDFPVDLEISLKELIETTGTKEIFDFFNLFYDLS 636

  Fly   590 ----------TILPTESALPMTSLMSQK-NLTIF-----------QRLLEASG---------YDD 623
                      .::||.|::|::.:.:.. ||..|           |.||:.:|         .:.
Yeast   637 SIIWNNEEYSLLVPTASSIPLSGITANSTNLRKFLELHLIPANVTQNLLDCNGSISTKLGTKLNC 701

  Fly   624 QFDDLDNVTIFAPTDKALQNTEWARMLKEQPELLNHNLD-----------LLEFLN---YHVVKP 674
            :.|.||||.:      ::|. :|.:.::........||.           .|.:||   ||:..|
Yeast   702 RKDHLDNVFV------SIQG-DWTKEVRVLKTGCTTNLKSSCIFLIDKPISLSWLNSEKYHLRLP 759

  Fly   675 MIKTCDLSEKSLPTVAGSSVRLNLYSTHALFSDVMNRATVNCARLVHFDDESCGSVLH-----QV 734
            .|..      ....:.|.::.::|     ||..::.|.               |.|..     :.
Yeast   760 GIAV------GFGVIIGVTIAISL-----LFCIIITRG---------------GKVKDKNQRGRN 798

  Fly   735 DRALAPPKNNMLKLLE-----ANPNYSKFLELVRKANLTQLLSNDSRSLTLLVPKNDI 787
            |||..|       |::     .||:||....|   :.|:|.....|.|:..:....||
Yeast   799 DRATTP-------LIQHSPIIHNPSYSATAHL---SPLSQPTFEGSYSVNAIQTPRDI 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfas	NP_788655.1	FAS1	339..450	CDD:214719	29/135 (21%)
		Fasciclin	462..592	CDD:280607	33/183 (18%)
		Fasciclin	607..740	CDD:280607	33/172 (19%)
		Fasciclin	753..875	CDD:280607	10/35 (29%)
YLR001C	NP_013101.1	Fasciclin	<36..>86	CDD:413430
		Fasciclin	78..468	CDD:413430	33/146 (23%)
		Fasciclin	493..603	CDD:413430	28/118 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344693
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2335
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10900
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1830
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960