Protein Alignment mfas and LOC5668272

DIOPT Version :10

• Sequence 1: NP_788655.1
• Gene: mfas / 41455
• FlyBaseID: FBgn0260745
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: XP_061513996.1
• Gene: LOC5668272 / 5668272
• VectorBaseID: AGAMI1_002865
• Length: 1268
• Species: Anopheles gambiae
• Alignment Length: 1272
• Identity: 238/1272 - (18%)
• Similarity: 384/1272 - (30%)
• Gaps: 494/1272 - (38%)

  Fly    13 SIQI-------QAVPFYGDSSSEE----VAEFDDSSDSTHESSDNSS------------------ 48
            ||||       ...||.|.||:::    .|.|...|::.|.....||
Mosquito    81 SIQIPVPPQPHSRQPFSGPSSTQQHFQPNAHFHHHSNNLHPPPPPSSPANGPVNSFRAPSGRPGP 145

  Fly    49 ------------------FMPHLTH----------------------------PLPAHRNLFAPL 67
                              |:|:...                            |.|.|.|..||:
Mosquito   146 SFGAQVNRYYFQHHTQTTFIPNFLQLLQQDTRLPPQQRSVQNQLQQATFFNGPPPPPHTNGPAPV 210

  Fly    68 PFAPLAPLEPQDPLHAQASQRMASVWNGPAPLAPQLHSS------HLLPLFSSGYDTEF------ 120
                      ..||::|.|..:.|: :.|...|||..:|      ...|.|:......|
Mosquito   211 ----------SQPLNSQPSSFLNSI-DTPTFGAPQRPNSLQAPFLQTPPSFTGNGQVRFPSQGAP 264

  Fly   121 ----------VPLEHQQQ--------------PQGRQETAATVP----AQTPSGVEQKPFNVDTI 157
                      |||...||              |...|.|....|    :|:.:...|.|....:|
Mosquito   265 SNGANLGQQPVPLFTNQQLPLHNSPQNFKLSGPNAGQSTFPVQPTFHNSQSVNPALQFPPVSQSI 329

  Fly   158 TTDVNSPNPAIFFQQ------------SFPF--FGNEFFNSFGGFGFGAAQE--PWWKGPNVCTE 206
            .|:...|:|.  |||            :.||  ..|.|.....|.||..||.  ..:.||....:
Mosquito   330 GTNFQQPSPQ--FQQQQQQQQLPRLQPNVPFAQSSNNFNAQPQGAGFPQAQPQIQTFSGPQQPVQ 392

  Fly   207 ----------------------------------KEEDETVASETEAEETV-------------- 223
                                              |||.|.:....|.::.:
Mosquito   393 SAQFGGQATNFNGLQQQQQQPLSYQQQQEYERRLKEESERIRELQEKQKVIQKHEQFLQKQYQKQ 457

  Fly   224 ----------------------------DTFGQERDGVTNVVRS--------PLFGQF------- 245
                                        ..:.|::..|...|||        .||.:.
Mosquito   458 QAKVQQLHQEFLKKQQKILQQQQQQQQQQQYEQQQKTVPTQVRSRDVLPSERTLFEKAVKMQSKP 522

  Fly   246 ----------------QFSVNSCAEKPNKHVCTKIVNQNGKKKTLTLTRQCCY-----GYGRPRN 289
                            |.||  ...|||.......:.|:.....|:..||..:     ...:|..
Mosquito   523 VAVPEPTTSTAAATSGQLSV--IPLKPNSKKDYSSITQSDLDVLLSANRQTLFQTIKSETAKPAK 585

  Fly   290 ADFTTPCEKIDIKDVEATASDMGAKQF-LESARTAGELADMLGAGSGKKVTLFVPNDAAFMEYRG 353
            |..|      .:|..:|...|...||. |..|.|:.:    ||..:.....|.:||.......|.
Mosquito   586 AKPT------KVKSTKALGRDDLLKQLKLALAETSPD----LGGKNYSSTDLVLPNGEKVQVIRT 640

  Fly   354 HHQQENNVEDAKAEA------SKPSIYKLHAVLGEVQLEDVPNEKLL----------QTE----- 397
            ...:.....:|.:|.      ..|:..|      .:..||:....||          |||
Mosquito   641 TDPEIIKRANANSEGVLTQQLDSPTTPK------PLSFEDIARSGLLPPGADFELIKQTEDGQIQ 699

  Fly   398 ----LPDQKIRI----------NSYQLPAALG---LEPYRFAANCVPIEKHDKLSEQAL-----V 440
                :|.|| ::          .||::....|   .|.....|:...|.|..|..|..|     |
Mosquito   700 EVGKIPPQK-KVTFVYLEEQDDGSYKVQGVKGSGDKETKTSGADVDSILKRIKNGEIQLPPPSSV 763

  Fly   441 HTLGGVLKPLTKNLMDIIRERADMSIMRTVLEKTNLSAMLEDDKPVTIFVPTDAAFDK-----LE 500
            .:.|.|.||      |:|                       :|.|:|...|......|     :.
Mosquito   764 VSKGSVAKP------DLI-----------------------EDAPITTTTPRHQPIKKANSVTII 799

  Fly   501 PHLRRALKEGRGCASNILKNHLLDLTFCSLATV--------------------PGAKTTAYNLLG 545
            ||            |..:::| ....|.|.:|:                    |.:..|||:..|
Mosquito   800 PH------------STPIEDH-ASTAFLSGSTIHHTASPAPATIYASTPSPASPSSGVTAYSPGG 851

  Fly   546 EPLLLNRTHRAANQTGPTPI---YI-NNLAKIIDADIMGT--------------------NGVLH 586
            ..........:|..:.|:|:   || ::.|:..:|:.:.|                    |...:
Mosquito   852 YSGSTLPQQVSARLSTPSPVSGSYIADSTARFSEANSVYTPVSTTAIPPATPAPSIYQTANTEKY 916

  Fly   587 VIDT-------------------------------ILPTESA--------------LPMTSLMSQ 606
            ..||                               .:||.||              .|......|
Mosquito   917 FSDTATAAAIEQQQQTASTYQHQTIHASHQSTASDAVPTASASETITQQQQDNTLSAPKEDTQQQ 981

  Fly   607 KN----------LTIFQRLLEASGYDDQFDDLDNVTIFAPTDKALQN--TEWARMLKEQPELLNH 659
            :|          |....:.|..||.|...::....|||.|||||.::  .:.....|.:.:..|:
Mosquito   982 QNELPAILKNNGLFAMAKYLRQSGLDTILNETGPYTIFVPTDKAFRSLLVQLGGPEKAEEKFRNN 1046

  Fly   660 NLDLLEFLNYHVVKPMIKTCDL-SEKSLPTVAGSSVRLNLYSTH-ALFSDVMNRATVNCARLVHF 722
            ...|...|.:||:....:...| .|.:..::||:.:|:|.|:.| :.::|| ...|:|.|.:|.
Mosquito  1047 PRLLSGLLLHHVIPGSFEIASLQDEMTGVSLAGTQLRVNQYNMHDSEWNDV-KVTTINGAMVVP- 1109

  Fly   723 DDESC---GSVLHQVDRALAP-PKNNMLKLLEAN--PNYSKFLELVRKANLTQLLSNDS-RSLTL 780
            |.:..   ..:.|.|||.:.| |..::|:.|:::  ..::.||..:..:.::..|.|.. ::.|:
Mosquito  1110 DKQDIVIPQGIAHAVDRVMFPLPVGDILQTLQSDRERRFTHFLRALFASGMSDTLQNKGIKTYTV 1174

  Fly   781 LVPKNDIF-----EELNESGEGSKPADPMALVKTHIVEDVVCCAGIIPTNWPFVRSIESISGQHL 840
            ..|.:..|     |||.........|:  .||:.|:|...:..||:     .|.: ::.:..:..
Mosquito  1175 FAPTDAAFAHLSTEELTNLVTEKDQAE--ELVRKHVVPGTLFTAGM-----RFYQ-VKDVMAEGK 1231

  Fly   841 RITRDR---RPKIENAGVTKCDVVATNGILHEINDII 874
            .:|..:   :.|:.:..:...::..|||::|.|:.::
Mosquito  1232 TVTLQKTGGKIKVNDGYLQTSNIPTTNGVIHAIDSLL 1268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfas	NP_788655.1	FAS1	339..450	CDD:214719	32/153 (21%)
		Fasciclin	462..592	CDD:396845	28/209 (13%)
		Fasciclin	607..740	CDD:396845	39/149 (26%)
		Fasciclin	753..875	CDD:396845	25/131 (19%)
LOC5668272	XP_061513996.1	None