Protein Alignment mfas and CG43333

DIOPT Version :10

• Sequence 1: NP_788655.1
• Gene: mfas / 41455
• FlyBaseID: FBgn0260745
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_788051.1
• Gene: CG43333 / 34830
• FlyBaseID: FBgn0263038
• Length: 1166
• Species: Drosophila melanogaster
• Alignment Length: 1056
• Identity: 206/1056 - (19%)
• Similarity: 363/1056 - (34%)
• Gaps: 321/1056 - (30%)

  Fly    17 QAVPFYGDSSSEEVAEFDDSSDSTHESSDNSSFMPHLTHPLPAHRNLFAPLPFAPLAPLEP---- 77
            |.:|       ::.::|:....|:.:  ......|.|..|:|   .:|:.:...|..  ||
  Fly   233 QTIP-------QQQSQFNYQPQSSQQ--QQYQLTPQLGLPVP---QIFSNVQATPFP--EPTRGS 283

  Fly    78 ----QDPLHAQASQRMASVWNGPAPLAPQL------HSSHLLPLFSSGYDTEFVPLEHQ------ 126
                |.|:  |..|......|.|:|:.||.      :...|:.........::...:|:
  Fly   284 FQQQQQPV--QQPQFQHQFVNAPSPIQPQAQPADQEYKQKLIQKHEQFVAKQYEKSQHKVRQQHE 346

  Fly   127 ----QQPQGRQETAATVPAQTPSGVEQKPFNVDTITTDVNSP-------NPAIFFQQSFPFFGNE 180
                :|.|.:|....|:..|..:..:..|:        |.:|       :|..:.|
  Fly   347 EFLLKQHQIKQHILPTIVTQHNANYQNSPY--------VAAPARGRPVAHPTEYNQ--------- 394

  Fly   181 FFNSFGGFGFGAAQEPWWKGPNVCTEKEEDETVASETEAEETVDTFGQERDGVTNVVRSPLFGQF 245
             |||       |.|:.:.:.|...|   ...|..:.|||..|
  Fly   395 -FNS-------ALQQYYKEHPTTTT---TTTTTTTTTEATTT----------------------- 425

  Fly   246 QFSVNSCAEKPNKHVCTKIVNQNGKKKTLTLTRQCCYGYGRPRNADFTTPCEKIDIKDVEATASD 310
                      |.|::..::.::.||                       .|.:| ..|.|:..|.|
  Fly   426 ----------PKKNIYAQVKSELGK-----------------------FPSQK-SKKPVKTIARD 456

  Fly   311 MGAKQFLESARTAGELADMLGAGSGKKVTLFVPNDAAFMEYRGHHQQENNVEDAKAEASK--PSI 373
            ...|| |::|.:......:.|..:..::.|.:||.......|  ....|.|:..||.:.:  .::
  Fly   457 DLLKQ-LKAALSEAPQQPLTGNKTYDEMDLVLPNGQRVQVIR--TTDPNLVQGQKAYSQEQLQTL 518

  Fly   374 YKLHAVLGE--VQLEDVPNEKLLQTELPD----QKIR---------INSYQLPAALGLEPY---- 419
            ....|:.||  :.|.||...|....|||.    |.:|         :.|..||..:.|...
  Fly   519 LAQQALGGETKLSLSDVAPSKSKDLELPGGGKVQILRSPDPQESDTLPSGSLPGGVDLSSLAALY 583

  Fly   420 ---------------RFAANCVPIEKHD------KLSEQALV---HTLGGV-------------- 446
                           ..|::.|.....|      :|:::.|:   :.:.|:
  Fly   584 GGGAGDIQGISNGANSIASSAVITSDSDEPPSLEELAKRGLIPDGYEIEGLSPKSQAPATAAPPT 648

  Fly   447 LKPLTKNLMDIIRERADMSI-------------------MRTVLEKTNLSAM----------LED 482
            |.|..|.....:.|:.|.|.                   :.::||:.....:          |.:
  Fly   649 LPPKKKATYVYLEEQTDGSFKIQGVKANGEKETKQTGSEVESILERIRSGEIKLPPSVSRLTLPN 713

  Fly   483 DK---------------PVTIFVPTDAAFDKLEPHLRRALKEGRGCASNILKNH-LLDLTFCSLA 531
            |:               |.|....|........|.:      .||..||..:.| ....|..:..
  Fly   714 DELVEIKSGKIIQTTRAPTTTTSTTTTTTTTPTPFI------SRGTPSNHRQYHPSRTSTTTTTT 772

  Fly   532 TVPGAKTTA-YNLLGEPLLLNRTHRAANQTGPTPIY---------------------------IN 568
            |...|.||| :||:.|....:....:..:|..:|||                           :.
  Fly   773 TTTTAPTTARHNLIFESSTSHVNAASLIRTTTSPIYGGSTVTVSPYLEGVSTHLPVVTERLSDVA 837

  Fly   569 NLAKII-------DADIMGTNGVLHVIDTILPTESAL-----PMTSLMSQKNLTIFQRLLEASGY 621
            |.|:::       ||.:..|...........||.|.|     .:..::....|....:.|..||.
  Fly   838 NNAELLPPIPQYADALVQETENTEKAAQANPPTSSVLSNPSEDLLQILKTNGLFAMAKYLRQSGL 902

  Fly   622 DDQFDDLDNVTIFAPTDKALQN-------TEWA-RMLKEQPELLNHNLDLLEFLNYHVVKPMIKT 678
            |...::....|||.|||||.:|       .|.| ...:..|.||:      ..|.:||:....:.
  Fly   903 DSILNETGPYTIFVPTDKAFKNLLVQLGGPERAEEKFQSNPRLLS------GLLLHHVIPGAFEI 961

  Fly   679 CDL-SEKSLPTVAGSSVRLNLYSTHALFSDVMNRATVNCARLV--HFDDESCGSVLHQVDRALAP 740
            ..| .|.:..::||:.:|:|.|:.|....:.:...|:|.|.:|  ..|.:....|.|.|||.:.|
  Fly   962 ATLQDEMTGVSLAGTQLRVNQYNMHDQEWNDVTLTTINGAMVVLNKKDIKIPQGVAHAVDRVMFP 1026

  Fly   741 -PKNNMLKLLEAN--PNYSKFLELVRKANLTQ-LLSNDSRSLTLLVPKNDIFEELNESG-----E 796
             |..::|:.|:::  ..:|.||:::..:.|:: |.|...::.|:..|.:..|.||:...     .
  Fly  1027 LPVGDILQTLQSDREGRFSNFLKILYTSGLSEKLQSKGVKTYTVFAPVDKSFSELDSDTLEKLYN 1091

  Fly   797 GSKPADPMALVKTHIVEDVVCCAGIIPTNWPFVRSIESIS-GQH--LRITRDRRPKIENAGVTKC 858
            ....|:..|:  .|||...:..||:     .|.:..:|:| |:.  |:.|...:.|:.:|.:...
  Fly  1092 DKDTAEQFAM--KHIVPGALFSAGM-----RFYQVKDSLSTGKTVILQKTSAGKIKVNDAQMVTS 1149

  Fly   859 DVVATNGILHEINDII 874
            ::.||||::|.::.::
  Fly  1150 NIPATNGVIHALDGVL 1165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mfas	NP_788655.1	FAS1	339..450	CDD:214719	31/169 (18%)
		Fasciclin	462..592	CDD:396845	33/209 (16%)
		Fasciclin	607..740	CDD:396845	40/143 (28%)
		Fasciclin	753..875	CDD:396845	31/131 (24%)
CG43333	NP_788051.1	Activator_LAG-3	<302..373	CDD:151935	12/70 (17%)
		Fasciclin	889..1026	CDD:396845	40/142 (28%)
		Fasciclin	1042..1165	CDD:396845	31/129 (24%)