DRSC/TRiP Functional Genomics Resources

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Protein Alignment mfas and Stab2

DIOPT Version :9

Sequence 1:NP_788655.1 Gene:mfas / 41455 FlyBaseID:FBgn0260745 Length:905 Species:Drosophila melanogaster
Sequence 2:NP_619614.1 Gene:Stab2 / 192188 MGIID:2178743 Length:2559 Species:Mus musculus


Alignment Length:288 Identity:81/288 - (28%)
Similarity:131/288 - (45%) Gaps:63/288 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   485 PVTIFVPTDAAFDKLEPHLRRALKEGRGCASNILKNHLLDLTFCSLATVPGAK--TTAYNLLGEP 547
            |.|:|||:..:|:. |..|:  :.:.:|..|.||:.|::   .|....:...|  |:|..|.|||
Mouse  1636 PFTVFVPSSDSFNS-ESKLK--VWDKQGLMSQILRYHVV---ACQQLLLENLKVITSATTLQGEP 1694

  Fly   548 LLLNRTHRAANQTGPTPIYINNLAKIIDADIMGTNGVLHVIDTILPTES------------ALPM 600
            :.::        .....:.||..||::.:||:.||||:|||||:|..::            .|.:
Mouse  1695 ISIS--------VSQDTVLINKKAKVLSSDIISTNGVIHVIDTLLSPQNLLITPKGASGRVLLNL 1751

  Fly   601 TSLMSQKNLTIFQRLLEASGYDDQFDDLDN--VTIFAPTDKALQNTEWARMLKEQPELL--NHNL 661
            |::.:....|.|.:|::.||......|..:  ||:|.|||||||     .:.:||.:.|  ..|.
Mouse  1752 TTVAANHGYTKFSKLIQDSGLLKVITDPMHTPVTLFWPTDKALQ-----ALPQEQQDFLFNEDNK 1811

  Fly   662 DLLE-FLNYHVVKPMI------------KTCDLSEKSLPTVAGSSVRLNLYSTHALFSDVMNRAT 713
            |.|: :|.:||::..:            ||...||.|:....||.|. .|:....:...:..|  
Mouse  1812 DKLKAYLKFHVIRDTMALASDLPRSASWKTLQGSELSVRCGTGSDVG-ELFLNGQMCRIIQRR-- 1873

  Fly   714 VNCARLVHFDDESCGSVLHQVDRALAPP 741
                  :.||    |.|.:.:|..|..|
Mouse  1874 ------LLFD----GGVAYGIDCLLMDP 1891

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mfasNP_788655.1 FAS1 339..450 CDD:214719
Fasciclin 462..592 CDD:280607 36/108 (33%)
Fasciclin 607..740 CDD:280607 41/149 (28%)
Fasciclin 753..875 CDD:280607
Stab2NP_619614.1 EGF_3 254..283 CDD:289699
EGF_3 334..369 CDD:289699
Fasciclin 390..512 CDD:280607
Fasciclin 533..661 CDD:280607
EGF_3 844..872 CDD:289699
EGF_3 928..959 CDD:289699
EGF_3 965..1001 CDD:289699
Fasciclin 1018..1137 CDD:280607
Fasciclin 1156..1273 CDD:280607
EGF_3 1482..1518 CDD:289699
EGF_3 1524..1560 CDD:289699
EGF_3 1566..1602 CDD:289699
Fasciclin 1628..1733 CDD:280607 37/110 (34%)
Fasciclin 1758..1889 CDD:280607 40/148 (27%)
EGF_3 2094..2129 CDD:289699
EGF_3 2135..2172 CDD:289699
Link_Domain 2206..2297 CDD:295393
FAS1 2363..2452 CDD:214719
Interaction with TMSB4X. /evidence=ECO:0000250 2510..2520
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2514..2559
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 54 0.196 Domainoid score I11151
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1830
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.940

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