Protein Alignment CG3397 and AKR1C3

DIOPT Version :9

• Sequence 1: NP_650140.1
• Gene: CG3397 / 41454
• FlyBaseID: FBgn0037975
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_001240837.1
• Gene: AKR1C3 / 8644
• HGNCID: 386
• Length: 323
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 76/331 - (22%)
• Similarity: 129/331 - (38%)
• Gaps: 99/331 - (29%)

  Fly    54 REEGILTVQEAIRSGINYIDTAPFYGQGKSEELLGQALK------DVPREAYYIATKV----ARY 108
            |.:.:...:.||.:|..:||:|..|   .:||.:|.|::      .|.||..:..:|:    .|.
Human    31 RSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRP 92

  Fly   109 ELDPNNMFDYTAAKARESVKRSLELLQLDRVDVLQVH--------------DVDAAPSLDMV-LN 158
            ||            .|.:::.||:..|||.||:..:|              |.:.....|:| |.
Human    93 EL------------VRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLC 145

  Fly   159 ETIPVLEEYVQAGKARFIGVTAYDVDVLKECAERGKGRIQVVLN------------------YAR 205
            .|...:|:...||.|:.|||:.::           :.:::::||                  :.|
Human   146 TTWEAMEKCKDAGLAKSIGVSNFN-----------RRQLEMILNKPGLKYKPVCNQVECHPYFNR 199

  Fly   206 YTLLDNTLLRHMKAFQEMGVGVVCAAAHSLGLLSNAGPQSW-HPGSPELL------AVGKRGAEI 263
            ..|||....:          .:|..|..:||   :...:.| .|.||.||      |:.|:
Human   200 SKLLDFCKSK----------DIVLVAYSALG---SQRDKRWVDPNSPVLLEDPVLCALAKK---- 247

  Fly   264 CQKRNVELGKLAMYYTMQLDGAATFLIGIPNRKLLRINLDAIFDGLTSHEQEVLQYLRENV-FTK 327
             .||...|  :|:.|  ||......|....|.:.:|.|:......||:.:.:.:..|..|: :..
Human   248 -HKRTPAL--IALRY--QLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFN 307

  Fly   328 SYSWGS 333
            |.|:.|
Human   308 SDSFAS 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	Tas	22..304	CDD:223739	69/299 (23%)
		Aldo_ket_red	24..322	CDD:294321	72/317 (23%)
AKR1C3	NP_001240837.1	ARA1	9..305	CDD:223729	73/321 (23%)
		Tas	17..297	CDD:223739	71/313 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840