Protein Alignment CG3397 and AKR7A2

DIOPT Version :9

• Sequence 1: NP_650140.1
• Gene: CG3397 / 41454
• FlyBaseID: FBgn0037975
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_003680.2
• Gene: AKR7A2 / 8574
• HGNCID: 389
• Length: 359
• Species: Homo sapiens
• Alignment Length: 324
• Identity: 66/324 - (20%)
• Similarity: 114/324 - (35%)
• Gaps: 85/324 - (26%)

  Fly    53 DREEGILTVQEAIRSGINYIDTAPFYGQGKSEELLGQ----------ALKDVPREAYYIATKVAR 107
            |.......|:..:..|...:|||..|..|:||.:||.          .:|        ||||...
Human    52 DAPASAAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK--------IATKANP 108

  Fly   108 YE---LDPNNMFDYTAAKARESVKRSLELLQLDRVDVLQVHDVDAAPSLDMVLNETIPVLEEYVQ 169
            ::   |.|:::        |..::.||:.||..:||:..:|    ||.....:.||:...:...|
Human   109 WDGKSLKPDSV--------RSQLETSLKRLQCPQVDLFYLH----APDHGTPVEETLHACQRLHQ 161

  Fly   170 AGKARFIGVTAYD----VDVLKECAERG-------KGRIQVVLNYARYTLLDNTLLRH----MKA 219
            .||...:|::.|.    .::...|...|       :|............|.  ..|||    ..|
Human   162 EGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELF--PCLRHFGLRFYA 224

  Fly   220 FQEMGVGVVCA--------AAHSLG-LLSNAGPQS-----WHPGSPELLAVGKRGAEICQKRNVE 270
            :..:..|::..        ....:| ...|:..::     |.....|.:|:.::..:.....:..
Human   225 YNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAP 289

  Fly   271 LGKLA----MYYTMQLDGA--ATFLIGIPNRKLLRINLDAIFDG---------------LTSHE 313
            ....|    ||:..||.||  ...::|:.:.:.|..||.|..:|               |.:||
Human   290 SVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHE 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	Tas	22..304	CDD:223739	61/298 (20%)
		Aldo_ket_red	24..322	CDD:294321	66/324 (20%)
AKR7A2	NP_003680.2	Aldo_ket_red	26..346	CDD:119408	63/315 (20%)
		Tas	42..355	CDD:223739	66/324 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158417
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D396894at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750