DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3397 and ARA2

DIOPT Version :9

Sequence 1:	NP_650140.1	Gene:	CG3397 / 41454	FlyBaseID:	FBgn0037975	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_013755.1	Gene:	ARA2 / 855057	SGDID:	S000004644	Length:	335	Species:	Saccharomyces cerevisiae

Alignment Length:	324	Identity:	96/324 - (29%)
Similarity:	170/324 - (52%)	Gaps:	34/324 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 VSKIALGGATLSKLFSDDFDREEGIL---TVQEAIRSGINYIDTAPFYGQGKSEELLGQALKDV- 94
            ||.:.||||.|::.::|:   .|.|.   .::.|...|||.|||:|:|  |.||.|.|:||.::
Yeast    14 VSPLVLGGAILNQQYTDE---PESIPLEDIIKYAFSHGINAIDTSPYY--GPSEVLYGRALSNLR 73

  Fly    95 ---PREAYYIATKVARYELDPNNMFDYTAAKARESVKRSLELLQLDRVDVLQVHDVDAAPSLDMV 156
               ||:.|:|.|||.|...:.   |:|:....|.||.||.|.|....:|::.:|||:.....|::
Yeast    74 NEFPRDTYFICTKVGRIGAEE---FNYSRDFVRFSVHRSCERLHTTYLDLVYLHDVEFVKFPDIL 135

  Fly   157 LNETIPVLEEYVQAGKARFIGVTAYDVDVL----KECA--ERGKGRIQVVLNYARYTLLDNTLLR 215
              |.:..|......|..:..|::.|.:|.:    :.|:  |...|.:..||:|....|.:|.||.
Yeast   136 --EALKELRTLKNKGVIKNFGISGYPIDFITWLAEYCSTEESDIGSLDAVLSYCNLNLQNNKLLN 198

  Fly   216 -HMKAFQEMGVGVVC-AAAHSLGLLSNAGPQSWHPGSPELLAVGKRGAEICQKRNVELGKLAMYY 278
             ..:..:...:.:|| |:..|:.||.:...:.:||.|.||.....:.|:.||::||:|..||..|
Yeast   199 FRERLLRNAKLKMVCNASILSMSLLRSQETRQFHPCSHELRECASQAAKYCQEQNVDLADLATRY 263

  Fly   279 TM-QLDGAATFLIGIPNRKLLRINLD------AIFDGLTSHEQEVLQYLRENVFTKSYS--WGS 333
            .: :..|....::|:.:.:.|::.||      :..:.|:|.:.::::|:::|:|.:.::  |.|
Yeast   264 AISEWVGKGPVVLGVSSMEELKLALDNYEIVKSNGNRLSSKDGQLVEYIQKNIFKEHFNEEWSS 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	Tas	22..304	CDD:223739	89/291 (31%)
CG3397	NP_650140.1	Aldo_ket_red	24..322	CDD:294321	92/309 (30%)
ARA2	NP_013755.1	AKR_ARA2	2..301	CDD:381390	89/296 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346031
Domainoid	1	1.000	122	1.000	Domainoid score	I1236
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I1226
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57996
OrthoFinder	1	1.000	-	-		FOG0006717
OrthoInspector	1	1.000	-	-		otm46794
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.860