DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3397 and AAD4

DIOPT Version :9

Sequence 1:	NP_650140.1	Gene:	CG3397 / 41454	FlyBaseID:	FBgn0037975	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_010038.1	Gene:	AAD4 / 851354	SGDID:	S000002402	Length:	329	Species:	Saccharomyces cerevisiae

Alignment Length:	307	Identity:	73/307 - (23%)
Similarity:	124/307 - (40%)	Gaps:	60/307 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 DREEGILTVQEAIRSGINYIDTAPFYGQGKSEELLGQALKDVP-REAYYIATKVA----RYELDP 112
            ::|:....:.....:|.|.||||..|...:||..:|:.:|... |:...||||..    :||:..
Yeast     5 NKEQAFELLDAFYEAGGNCIDTANSYQNEESEIWIGEWMKSRKLRDQIVIATKFTGDYKKYEVGG 69

  Fly   113 NNMFDYTAAKARE---SVKRSLELLQLDRVDVLQVHDVDAAPSLDMVLNETIPVLEEYVQAGKAR 174
            ....:|.......   ||:.||..||.|.:|:|.||..|...|::.|::.    |...||.||..
Yeast    70 GKSANYCGNHKHSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEVMDS----LHILVQQGKVL 130

  Fly   175 FIGVT---AYDVDVLKECA-ERGKGRIQV------VLN-----------------YARYTLLDNT 212
            ::||:   |:.|......| ..||....:      |||                 .|.:.::...
Yeast   131 YLGVSDTPAWVVSAANYYATSHGKTPFSIYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGG 195

  Fly   213 LLRHMKAFQEM---GVGVVCAAAHSLGLLSNAGPQSWHPGSPELLAVGKRGAEICQKRNVE-LGK 273
            ..:..||.:|.   |.|        |..:|....|     :.:.:.:.:..|::.::...| :..
Yeast   196 RFQSKKAMEERKKNGEG--------LRTVSGTSKQ-----TDKEVKISEALAKVAEEHGTESVTA 247

  Fly   274 LAMYYTMQLDGAATFLIGIPNRKL--LRINLDAIFDGLTSHEQEVLQ 318
            :|:.|..........|:|  .||:  |:.|::|:...||..:.|.|:
Yeast   248 IAIAYVRSKAKNVFPLVG--GRKIEHLKQNIEALSIKLTPEQIEYLE 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	Tas	22..304	CDD:223739	68/291 (23%)
CG3397	NP_650140.1	Aldo_ket_red	24..322	CDD:294321	73/307 (24%)
AAD4	NP_010038.1	AKR_AKR9A3_9B1-4	1..292	CDD:381373	72/305 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810