Protein Alignment CG3397 and KCNAB1

DIOPT Version :10

• Sequence 1: NP_650140.1
• Gene: CG3397 / 41454
• FlyBaseID: FBgn0037975
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_751892.1
• Gene: KCNAB1 / 7881
• HGNCID: 6228
• Length: 419
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 90/350 - (25%)
• Similarity: 149/350 - (42%)
• Gaps: 68/350 - (19%)

  Fly    22 MEYRQLGSTGLRVSKIALG-GATLSKLFSDDFDREEGILTVQEAIRSGINYIDTAPFYGQGKSEE 85
            |.:|.||.:|||||.:.|| ..|.....||:.  .|.::|:  |..||:|..|||..|..||:|.
Human    89 MPHRNLGKSGLRVSCLGLGTWVTFGGQISDEV--AERLMTI--AYESGVNLFDTAEVYAAGKAEV 149

  Fly    86 LLGQALKDV--PREAYYIATKVARYELDPNNMFDYTAAKAR-----------ESVKRSLELLQLD 137
            :||..:|..  .|.:..|.||:            |...||.           |.:|.||:.|||:
Human   150 ILGSIIKKKGWRRSSLVITTKL------------YWGGKAETERGLSRKHIIEGLKGSLQRLQLE 202

  Fly   138 RVDVLQVHDVDAAPSLDMVLNETIPVLEEYVQAGKARFIGVTAYDVDVLKEC--AERGKGRIQVV 200
            .|||:..:    .|..:..:.|.:..:...:..|.|.:.|.:.:....:.|.  ..|....|..|
Human   203 YVDVVFAN----RPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPV 263

  Fly   201 LNYARYTLL--DNTLLRHMKAFQEMGVGVVCAAAHSLGLLS----NAGPQS---------WHPGS 250
            ...|.|.|.  :...::..:.:.::|||.:..:..:.|::|    |..|:|         |   .
Human   264 CEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQW---L 325

  Fly   251 PELLAVGKRG----------AEICQKRNVELGKLAMYYTMQLDGAATFLIGIPNRKLLRINLDAI 305
            .|.: |.:.|          :.|.::....|.:||:.:.::.:|.::.|:|....:.|..||.||
Human   326 KERI-VSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAI 389

  Fly   306 --FDGLTSH-EQEVLQYLRENVFTK 327
              ...:||| ..|:...||...::|
Human   390 QVLPKMTSHVVNEIDNILRNKPYSK 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	AKR_galDH	22..315	CDD:381389	86/336 (26%)
KCNAB1	NP_751892.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52
		AKR_KCAB1B_AKR6A3-like	89..411	CDD:381385	89/345 (26%)