Protein Alignment CG3397 and Akr1c3

DIOPT Version :10

• Sequence 1: NP_650140.1
• Gene: CG3397 / 41454
• FlyBaseID: FBgn0037975
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_612519.1
• Gene: Akr1c3 / 171516
• RGDID: 708428
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 366
• Identity: 91/366 - (24%)
• Similarity: 145/366 - (39%)
• Gaps: 98/366 - (26%)

  Fly    18 KVRRMEYRQLGSTGLRVSKIALGG-ATLSKLFSDDFDREEGILTVQEAIRSGINYIDTAPFYGQG 81
            |:::||.    :.|..:..:..|. ||...|      |::.:.:.:.||..|..:||.:..|
  Rat     4 KIQKMEL----NDGHSIPVLGFGTYATEENL------RKKSMESTKIAIDVGFRHIDCSHLY--- 55

  Fly    82 KSEELLGQALKD------VPREAYYIATKV----ARYELDPNNMFDYTAAKARESVKRSLELLQL 136
            ::||.:|||:..      |.||..:..:|:    .|.||            .|.|::.||..|.|
  Rat    56 QNEEEIGQAIVSKIEDGTVKREDIFYTSKLWSTSHRPEL------------VRPSLENSLRKLNL 108

  Fly   137 DRVDVLQVH-DVDAAPS-------------LDMV-LNETIPVLEEYVQAGKARFIGVTAYDVDVL 186
            |.||:..:| .|...|.             ||.| |.:|...:|:...||.|:.|||:.::...|
  Rat   109 DYVDLYLIHFPVSLKPGDELLPQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQL 173

  Fly   187 KECAERGKGRIQVVLNYARYTLLDNTLLRHMKAFQEMGVGVVCAAAHSLG--------------L 237
            ::...:...:.:.|.|.....|..|.  ..:.|:.:|. .:|..|..:||              |
  Rat   174 EKILNKPGLKHRPVCNQVECHLYLNQ--SKLLAYCKMN-DIVLVAYGALGTQRYKYCINEDTPVL 235

  Fly   238 LSNAGPQSWHPGSPELLAVGKRGAEICQKRNVELGKLAMYYTMQLDGAATFLIGIPNRKLLRINL 302
            |.:          |.|..:.|:     .||...|  :|:.|  ||:.....|:...|.:.:|.||
  Rat   236 LDD----------PILCTMAKK-----YKRTPAL--IALRY--QLERGIVTLVKSFNEERIRENL 281

  Fly   303 DAIFD-GLTSHEQEVLQYLRENVFTKSYSWGSTLSTVNMFK 342
            . :|| .|.|.:.|:|..|..|:         .....||||
  Rat   282 Q-VFDFQLASDDMEILDNLDRNL---------RYFPANMFK 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	AKR_galDH	22..315	CDD:381389	82/333 (25%)
Akr1c3	NP_612519.1	AKR_AKR1C1-35	6..308	CDD:381334	86/358 (24%)