Protein Alignment CG3397 and AKR1C2

DIOPT Version :9

• Sequence 1: NP_650140.1
• Gene: CG3397 / 41454
• FlyBaseID: FBgn0037975
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_001345.1
• Gene: AKR1C2 / 1646
• HGNCID: 385
• Length: 323
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 77/310 - (24%)
• Similarity: 131/310 - (42%)
• Gaps: 76/310 - (24%)

  Fly    54 REEGILTVQEAIRSGINYIDTAPFYGQGKSEELLGQALK------DVPREAYYIATKV----ARY 108
            :.:.:..|:.||.:|.::||:|..|   .:||.:|.|::      .|.||..:..:|:    .|.
Human    31 KSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRP 92

  Fly   109 ELDPNNMFDYTAAKARESVKRSLELLQLDRVDVLQVH-DVDAAPSLDM--------VLNETIPV- 163
            ||            .|.:::|||:.||||.||:..:| .|...|..::        :|.:|:.:
Human    93 EL------------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLC 145

  Fly   164 -----LEEYVQAGKARFIGVTAYDVDVLKECAERGKGRIQVVLN-------YARYTLLDNTLLRH 216
                 :|:...||.|:.|||:.::..:|:....:...:.:.|.|       :.:..|||....:
Human   146 ATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSK- 209

  Fly   217 MKAFQEMGVGVVCAAAHSLGLLSNAGPQSW-HPGSPELL------AVGKRGAEICQKRNVELGKL 274
                     .:|..|..:||   :...:.| .|.||.||      |:.|:     .||...|  :
Human   210 ---------DIVLVAYSALG---SHREEPWVDPNSPVLLEDPVLCALAKK-----HKRTPAL--I 255

  Fly   275 AMYYTMQLDGAATFLIGIPNRKLLRINLDAIFDGLTSHEQEVLQYLRENV 324
            |:.|  ||......|....|.:.:|.|:......|||.|.:.:..|..||
Human   256 ALRY--QLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNV 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	Tas	22..304	CDD:223739	70/288 (24%)
		Aldo_ket_red	24..322	CDD:294321	75/306 (25%)
AKR1C2	NP_001345.1	AKR_AKR1C1-35	6..308	CDD:381334	77/310 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158411
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840