Protein Alignment CG3397 and Akr1b8

DIOPT Version :10

• Sequence 1: NP_650140.1
• Gene: CG3397 / 41454
• FlyBaseID: FBgn0037975
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_032038.1
• Gene: Akr1b8 / 14187
• MGIID: 107673
• Length: 316
• Species: Mus musculus
• Alignment Length: 314
• Identity: 74/314 - (23%)
• Similarity: 126/314 - (40%)
• Gaps: 72/314 - (22%)

  Fly    61 VQEAIRSGINYIDTAPFYGQGKSEELLGQAL------KDVPREAYYIATKVARYELDPNNMFDYT 119
            |:.||.:|..:||.|..|   .:|..:|:|:      |.|.||..:|.:|     |.| ..|:..
Mouse    32 VKAAIDAGYRHIDCAYAY---CNENEVGEAIQEKIKEKAVQREDLFIVSK-----LWP-TCFEKK 87

  Fly   120 AAKARESVKRSLELLQLDRVDVLQVH-------DVDAAPSLDM--VLN------ETIPVLEEYVQ 169
            ..|  |:.:::|..|:||.:|:..:|       ..:..|..|.  :|.      |....:||.|.
Mouse    88 LLK--EAFQKTLTDLKLDYLDLYLIHWPQGLQPGKELFPKDDQGRILTSKTTFLEAWEGMEELVD 150

  Fly   170 AGKARFIGVTAYDVDVLKECAERGKGRIQVVLNY--ARYTLLDNTLLRHMKAFQEMGVGVVCAAA 232
            .|..:.:||:.::           ..:|:.:||.  .::..:.|.:..|....||.    :....
Mouse   151 QGLVKALGVSNFN-----------HFQIERLLNKPGLKHKPVTNQVECHPYLTQEK----LIQYC 200

  Fly   233 HSLGL-------LSNAGPQSWHPGSPELLAVGKRGAEICQKRNVELGKLAMYYTMQLDGAATFLI 290
            ||.|:       |.:....|..|..|.||...|. .||..|......::.:.:.:|.:.......
Mouse   201 HSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKI-KEIAAKHEKTSAQVLIRFHIQRNVVVIPKS 264

  Fly   291 GIPNRKLLRINLDAIFDGLTSHEQ--EVLQYLRENVFTKSYSWGSTL--STVNM 340
            ..|:|  ::.|:. :||...|.|:  .:|.:.|        :|.:.|  .||||
Mouse   265 VTPSR--IQENIQ-VFDFQLSDEEMATILSFNR--------NWRACLLPETVNM 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3397	NP_650140.1	AKR_galDH	22..315	CDD:381389	66/285 (23%)
Akr1b8	NP_032038.1	AKR_AKR1B1-19	10..316	CDD:381333	74/314 (24%)